DOSIMETRIC COMPARISON OF SCALP AND ORGANS AT RISK WITH DIFFERENT RADIOTHERAPY TECHNIQUES IN MALIGN GLIAL TUMORS

Yıl 2018, Cilt: 44 Sayı: 2, 95 - 101, 01.08.2018

Oğuz Aydın , Süreyya Sarıhan , Duygu Bolat Habibe Altaş , Sema Gözcü Tunç , Zenciye Kıray

https://doi.org/10.32708/uutfd.431230

Öz

In
malign glial tumors treated with radiotherapy (RT); despite the current
treatment plan with volumetric arc (t-VMAT) technique, 1 arc VMAT and static 5
field intensity modulated RT technique wre compered dosimetrically. Sixteen malign
glial tumors treated with at least 50 Gy RT were included. Sixteen, 30 and 24
Gray thresholds doses were used for mean, 1 and 9 cc scalp volumes. There was
no statistically significant difference between methods in terms of planning
treatment volume and risky organ doses. Significant reductions in scalp doses
were observed (p < 0.05) with the inclusion of scalp regardless of the planning
methods. Despite the hair loss in acute period, there was no permanent hair
loss in any case in 12-month follow-up. It has been shown by this study, the
inclusion of scalp into the treatment plan does not have a negative effect on
the target volume doses, and our patients may be protected from cosmetic and
psychosocial side effects caused by permanent hair loss.

Anahtar Kelimeler

Malign glial tumor, radiotherapy techniques, scalp, hair-sparing treatment, dosimetry

Malign Glial Tümörlerde Farklı Radyoterapi Teknikleri ile Saçlı Deri ve Riskli Organların Dozimetrik Karşılaştırılması

Öz

Volumetrik ark (t-VMAT) tekniği ile radyoterapi (RT)
uygulanan malign glial tümörlü hastalarda mevcut tedavi planına karşın 1 ark
VMAT ve statik 5 alan yoğunluk ayarlı RT tekniği dozimetrik olarak
karşılaştırıldı. Çalışmaya en az 50 Gy RT alan 18 malign glial tümörlü olgu
dahil edildi. Saçlı deri ortalama, 1 ve 9 cc dozları için 16, 30 ve 24 Gray
eşik değerleri kullanıldı. Yöntemler arasında planlama tedavi volümü ve riskli
organ dozları açısından anlamlı fark bulunamadı.
Planlamanın hangi yöntem ile yapıldığı önemli olmaksızın saçlı derinin
planlamaya dahil edilmesiyle birlikte saçlı deri dozlarının anlamlı azaldığı
görüldü (p < 0.05). Oniki aylık izlem süresi içinde akut dönemde saç kaybı
yaşamalarına rağmen hiçbir olguda kalıcı saç kaybı görülmedi. Bu çalışma ile
saçlı derinin tedavi planına dahil edilmesinin hedef volüm dozları açısından
olumsuz etkisi olmadığı gibi hastalarımızın kalıcı saç dökülmesinin yaratacağı
kozmetik ve psikososyal yan etkilerden korunabileceği ortaya konulmuştur. 

Anahtar Kelimeler

malign glial tümör, radyoterapi tekniği, saçlı deri, saç koruyucu tedavi, dozimetri

Kaynakça

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