What is Subclinical Hypothyroidism? It should be treated?

Year 2018, Volume: 44 Issue: 2, 129 - 134, 01.08.2018

Özen Öz Gül Soner Cander Canan Ersoy

https://doi.org/10.32708/uutfd.435351

Abstract

Although serum free thyroid hormone levels are normal, high levels of
thyroid stimulating hormone is more frequent condition in population and is
defined as subclinical hypothyroidism. In general population 3-8 % is seen. Prevalance
of subclinical hypothyroidism increases with age and is more common in women.
Most important consequence of subclinical hypothyroidism is progression to
overt hypothyroidism. increased risk of cardiovascular disease and a decreased
cognitive functions due to subclinical hypothyroidism remains uncertain.
Therefore, the consensus about the benefits of levothyroxine treatment is not
available. In general, the level of thyroid stimulating hormone 10 mU/L, those
on treatment are recommended, which are below the level of treatment to be
personalized, consideration of patient age, risk factors are recommended.

Keywords

Subclinical hypothyroidism, thyroid function tests

Subklinik Hipotiroidi Nedir? Tedavi Edilmeli midir?

Abstract

Bireylerin serum
serbest tiroid hormon düzeyleri normal değerlerde iken tiroid uyarıcı hormon
düzeyinin yüksek olması toplumda oldukça sık görülen bir durumdur ve bu durum
subklinik hipotiroidi olarak tanımlanmaktadır. Subklinik hipotiroidi genel
populasyonda %3-8 oranında görülmekte, prevalansı yaşla birlikte artmakta ve
kadınlarda daha sık görülmektedir. Subklinik hipotiroidinin en önemli sonucu
aşikar hipotiroidiye ilerlemedir. Subklinik hipotiroidi ile kardiyovasküler
hastalıklarda artış ve bilişsel fonksiyonlarda azalma arasındaki ilişki kesin
olarak gösterilememiştir. Bu nedenle levotiroksin tedavisinin faydaları
konusunda da fikir birliği bulunmamaktadır. Genel olarak tiroid uyarıcı hormon düzeyi
10 mU/L’nin üzerinde olanlara tedavi önerilmekte, bu düzeylerin altında
olanlarda tedavinin kişiselleştirilmesi, hastaların risk faktörleri ve yaşları
göz önünde bulundurularak değerlendirilmeleri önerilmektedir.

Keywords

Subklinik hipotiroidi, tiroid fonksiyon testleri

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