Research Article
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Impact of Nephrology Follow-Up on Survival and Clinical Outcomes in Patients Initiating Emergency Dialysis

Year 2025, Volume: 51 Issue: 2, 255 - 261, 28.08.2025
https://doi.org/10.32708/uutfd.1704426

Abstract

This study aimed to evaluate the clinical and laboratory characteristics of patients presenting with emergency dialysis requirements and to assess the impact of nephrology follow-up on patient outcomes. In this retrospective study. patients who were given an emergency hemodialysis indication in the emergency department were divided into two groups according to the presence or absence of nephrology follow-up within the past year. Dialysis indications. laboratory findings. mortality rates. and transition to routine dialysis were analyzed. The most common indications for emergency dialysis were severe metabolic acidosis and elevated creatinine levels. The 28-day mortality rate was significantly lower in patients with nephrology follow-up (16.2% vs. 36.2%. p=0.001). The transition rate to routine hemodialysis was also higher in this group (p=0.024). However, there was no statistically significant difference between the groups regarding 90-day mortality or hospital readmission rates. Regular nephrology follow-up reduces short-term mortality and increases the transition to planned dialysis in patients requiring emergency dialysis. However, more effective monitoring and early intervention strategies are needed to improve long-term outcomes.

References

  • 1. Singbartl K. Joannidis M. Short-term effects of acute kidney injury. Crit Care Clin. 2015;31(4):751–62.
  • 2. Li PK. Burdmann EA. Mehta RL. Acute kidney injury: global health alert. Kidney Int. 2013;83(3):372–6. 3. Murdeshwar HN. Anjum F. Hemodialysis. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan–. [cited 2025 Jun 3]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK563296/
  • 4. Kramer A . P ippias M . N oordzij M . S tel V S. A fentakis N . Ambühl P M. e t a l. T he E RA-EDTA Registry Annual Report 2015: a summary. Clin Kidney J. 2018;11(1):108–22.
  • 5. Han G. Bohmart A. Shaaban H. Mages K. Jedlicka C. Zhang Y. et al. Emergency department utilization among maintenance hemodialysis patients: a systematic review. Kidney Med. 2021;4(2):100391.
  • 6. Loran MJ. McErlean M. Eisele G. et al. The emergency department care of hemodialysis patients. Clin Nephrol. 2002;57(6):439–43.
  • 7. Saran R. Robinson B. Abbott KC. et al. US Renal Data System 2019 Annual Data Report: epidemiology of kidney disease in the U nited S tates. A m J K idney Dis. 2020;75(1 Suppl 1):S1–S64.
  • 8. Baugh CW. Wang TJ. Caterino JM. et al. Emergency department management of patients with febrile neutropenia: guideline concordant or overly aggressive? Acad Emerg Med. 2017;24(1):83–91.
  • 9. Johansen KL. Gilbertson DT. Li S. Liu J. Roetker NS. Ku E. et al. U S R enal D ata S ystem 2 023 A nnual D ata R eport: Epidemiology of kidney disease in the United States. Am J Kidney Dis. 2024;83(4 Suppl 1):A8–A13.
  • 10. Pippias M. Kramer A. Noordzij M. Afentakis N. Alonso de la Torre R. Ambühl PM. et al. The ERA-EDTA Registry Annual Report 2014: a summary. Clin Kidney J. 2017;10(2):154–69.
  • 11. Morales KJM. Mondragon AR. Most frequent cause of dialysis emergency and precipitating factor in patients with chronic kidney disease attending the emergency department of HGZ 50 in San Luis Potosí. Mexico. Int J Crit Care Emerg Med. 2023;9:153.
  • 12. Ruiz-Mejía R. Ortega-Olivares LM. Naranjo-Carmona CA. Suárez-Otero R. Treatment of hyperkalemia in patients with chronic kidney disease on dialysis therapy. Internal Med Mex. 2017;33:778–96.
  • 13. Aktepe M. Akdeniz YS. İpekci A. Çakmak F. Altıparmak MR. İkizceli İ. Acil serviste hemodiyaliz endikasyonu konulan hastaların analizi. Phnx Med J. 2020;2(3):145–51.
  • 14. Özpolat Ç. Altunbaş E. Acil serviste acil hemodiyaliz endikasyonu konulan hastaların retrospektif analizi. Anatolian J Emerg Med. 2022;5(3):124–7. Monitoring and Outcomes in Emergency Dialysis 261
  • 15. Faubel S. Shah PB. Immediate consequences of acute kidney injury: the impact of traditional and nontraditional complications on mortality. Adv Chronic Kidney Dis. 2016;23(3):179–85.
  • 16. Kovesdy CP. Lott EH. Lu JL. Malakauskas SM. Ma JZ. Molnar MZ. et al. Hyponatremia. hypernatremia. and mortality in patients with chronic kidney disease with and without congestive heart failure. Circulation. 2012;125(5):677–84.
  • 17. Madan VD. Novak E. Rich MW. Impact of change in serum sodium concentration on mortality in patients hospitalized with heart failure and hyponatremia. Circ Heart Fail. 2011;4(5):637–43.
  • 18. Kim SG. Lee J. Yun D. et al. Hyperlactatemia is a predictor of mortality in patients undergoing continuous renal replacement therapy for acute kidney injury. BMC Nephrol. 2023;24:11.
  • 19. Chen M. Lv D . P rognostic value of s erum l actate level for mortality in patients with acute kidney injury. Eur J Med Res. 2024;29:295.
  • 20. Zhu X . X ue J . L iu Z . D ai W . X u H . Z hou Q. et al. The lactate/albumin ratio predicts mortality in critically ill patients with acute kidney injury: an observational multicenter study on the eICU database. Int J Gen Med. 2021;14:10511–25.
  • 21. Fang J. Wang M. Gong S. Cui N. Xu L. Increased 28-day mortality due to fluid overload prior to continuous renal replacement in sepsis associated acute kidney injury. Ther Apher Dial. 2022;26(2):288–96.
  • 22. Kim IY. Kim S . Y e B M. K im M J. Kim S R. L ee D W. e t a l. Effect of fluid overload on survival in patients with sepsisinduced acute kidney injury receiving continuous renal replacement therapy. Sci Rep. 2023;13(1):2796.

Acil Diyaliz Başlangıcında Nefroloji İzleminin Sağkalım ve Klinik Sonuçlar Üzerindeki Rolü

Year 2025, Volume: 51 Issue: 2, 255 - 261, 28.08.2025
https://doi.org/10.32708/uutfd.1704426

Abstract

Bu çalışma, acil diyaliz gereksinimi ile başvuran hastaların klinik ve laboratuvar özelliklerini. nefroloji takibinin hasta sonuçları üzerindeki etkisini değerlendirmeyi amaçlamaktadır. Bu retrospektif çalışmada. acil serviste acil hemodiyaliz endikasyonu konulan hastalar. Son bir yıl içinde nefroloji takibi bulunup bulunmamasına göre iki gruba ayrılarak karşılaştırılmıştır. Diyaliz endikasyonları, laboratuvar bulguları, mortalite oranları ve rutin diyaliz geçişleri analiz edilmiştir. Acil diyaliz endikasyonları arasında en sık ağır metabolik asidoz ve kreatinin yüksekliği saptanmıştır. Nefroloji takibi olan hastalarda 28 günlük mortalite oranı anlamlı olarak daha düşük bulunmuştur (%16,2 vs. %36,2. p=0,001). Rutin hemodiyaliz programına geçiş oranı nefroloji takibi olan grupta daha yüksek bulunmuştur (p=0,024). Ancak 90 günlük mortalite ve yeniden hastaneye yatış oranlarında gruplar arasında anlamlı fark izlenmemiştir. Düzenli nefroloji takibi, acil diyaliz gereksinimi olan hastalarda kısa dönem mortaliteyi azaltmakta ve planlı diyaliz geçişini artırmaktadır. Ancak uzun dönem sonuçlar için daha etkin izlem ve erken müdahale stratejilerine ihtiyaç vardır.

References

  • 1. Singbartl K. Joannidis M. Short-term effects of acute kidney injury. Crit Care Clin. 2015;31(4):751–62.
  • 2. Li PK. Burdmann EA. Mehta RL. Acute kidney injury: global health alert. Kidney Int. 2013;83(3):372–6. 3. Murdeshwar HN. Anjum F. Hemodialysis. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan–. [cited 2025 Jun 3]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK563296/
  • 4. Kramer A . P ippias M . N oordzij M . S tel V S. A fentakis N . Ambühl P M. e t a l. T he E RA-EDTA Registry Annual Report 2015: a summary. Clin Kidney J. 2018;11(1):108–22.
  • 5. Han G. Bohmart A. Shaaban H. Mages K. Jedlicka C. Zhang Y. et al. Emergency department utilization among maintenance hemodialysis patients: a systematic review. Kidney Med. 2021;4(2):100391.
  • 6. Loran MJ. McErlean M. Eisele G. et al. The emergency department care of hemodialysis patients. Clin Nephrol. 2002;57(6):439–43.
  • 7. Saran R. Robinson B. Abbott KC. et al. US Renal Data System 2019 Annual Data Report: epidemiology of kidney disease in the U nited S tates. A m J K idney Dis. 2020;75(1 Suppl 1):S1–S64.
  • 8. Baugh CW. Wang TJ. Caterino JM. et al. Emergency department management of patients with febrile neutropenia: guideline concordant or overly aggressive? Acad Emerg Med. 2017;24(1):83–91.
  • 9. Johansen KL. Gilbertson DT. Li S. Liu J. Roetker NS. Ku E. et al. U S R enal D ata S ystem 2 023 A nnual D ata R eport: Epidemiology of kidney disease in the United States. Am J Kidney Dis. 2024;83(4 Suppl 1):A8–A13.
  • 10. Pippias M. Kramer A. Noordzij M. Afentakis N. Alonso de la Torre R. Ambühl PM. et al. The ERA-EDTA Registry Annual Report 2014: a summary. Clin Kidney J. 2017;10(2):154–69.
  • 11. Morales KJM. Mondragon AR. Most frequent cause of dialysis emergency and precipitating factor in patients with chronic kidney disease attending the emergency department of HGZ 50 in San Luis Potosí. Mexico. Int J Crit Care Emerg Med. 2023;9:153.
  • 12. Ruiz-Mejía R. Ortega-Olivares LM. Naranjo-Carmona CA. Suárez-Otero R. Treatment of hyperkalemia in patients with chronic kidney disease on dialysis therapy. Internal Med Mex. 2017;33:778–96.
  • 13. Aktepe M. Akdeniz YS. İpekci A. Çakmak F. Altıparmak MR. İkizceli İ. Acil serviste hemodiyaliz endikasyonu konulan hastaların analizi. Phnx Med J. 2020;2(3):145–51.
  • 14. Özpolat Ç. Altunbaş E. Acil serviste acil hemodiyaliz endikasyonu konulan hastaların retrospektif analizi. Anatolian J Emerg Med. 2022;5(3):124–7. Monitoring and Outcomes in Emergency Dialysis 261
  • 15. Faubel S. Shah PB. Immediate consequences of acute kidney injury: the impact of traditional and nontraditional complications on mortality. Adv Chronic Kidney Dis. 2016;23(3):179–85.
  • 16. Kovesdy CP. Lott EH. Lu JL. Malakauskas SM. Ma JZ. Molnar MZ. et al. Hyponatremia. hypernatremia. and mortality in patients with chronic kidney disease with and without congestive heart failure. Circulation. 2012;125(5):677–84.
  • 17. Madan VD. Novak E. Rich MW. Impact of change in serum sodium concentration on mortality in patients hospitalized with heart failure and hyponatremia. Circ Heart Fail. 2011;4(5):637–43.
  • 18. Kim SG. Lee J. Yun D. et al. Hyperlactatemia is a predictor of mortality in patients undergoing continuous renal replacement therapy for acute kidney injury. BMC Nephrol. 2023;24:11.
  • 19. Chen M. Lv D . P rognostic value of s erum l actate level for mortality in patients with acute kidney injury. Eur J Med Res. 2024;29:295.
  • 20. Zhu X . X ue J . L iu Z . D ai W . X u H . Z hou Q. et al. The lactate/albumin ratio predicts mortality in critically ill patients with acute kidney injury: an observational multicenter study on the eICU database. Int J Gen Med. 2021;14:10511–25.
  • 21. Fang J. Wang M. Gong S. Cui N. Xu L. Increased 28-day mortality due to fluid overload prior to continuous renal replacement in sepsis associated acute kidney injury. Ther Apher Dial. 2022;26(2):288–96.
  • 22. Kim IY. Kim S . Y e B M. K im M J. Kim S R. L ee D W. e t a l. Effect of fluid overload on survival in patients with sepsisinduced acute kidney injury receiving continuous renal replacement therapy. Sci Rep. 2023;13(1):2796.
There are 21 citations in total.

Details

Primary Language English
Subjects Emergency Medicine
Journal Section Research Article
Authors

Evren Dal 0009-0003-7755-3703

Suna Eraybar 0000-0003-4306-9262

Publication Date August 28, 2025
Submission Date May 22, 2025
Acceptance Date July 20, 2025
Published in Issue Year 2025 Volume: 51 Issue: 2

Cite

AMA Dal E, Eraybar S. Impact of Nephrology Follow-Up on Survival and Clinical Outcomes in Patients Initiating Emergency Dialysis. Journal of Uludağ University Medical Faculty. August 2025;51(2):255-261. doi:10.32708/uutfd.1704426

ISSN: 1300-414X, e-ISSN: 2645-9027

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