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Pre-Operational and Post-Operational Motor Stimulated Potential, Electrophysiological Conduction Studies in Patients with Tethered Cord Syndrome, Neurological Examination and Comparison of Lumbosacral MRG Investigations

Yıl 2025, Cilt: 18 Sayı: 2, 116 - 122, 30.08.2025
https://doi.org/10.52976/vansaglik.1695373

Öz

Tethered Cord Syndrome (TCS) is a progressive neurologic disorder that is often overlooked in adults, especially in the pre-MRI era. However, it is still unknown whether electrophysiologic studies have any value in determining the outcome of surgery or their usefulness in follow-up. In this study, we aimed to describe the potential of preoperative motor evoked potentials (MEPs) to predict the response to surgical treatment and the change in MEP values after surgery in patients diagnosed with TCS.

Etik Beyan

The Ethical Committee of the University of Celal Bayar approved the study (2012/118). Our study was financially supported by Celal Bayar University Scientific Research Project Unit (2002/085)

Destekleyen Kurum

Celal Bayar university Scientific Research Project Unit (2002/085)

Proje Numarası

The Ethical Committee of the University of Celal Bayar approved the study (2012/118). Our study was financially supported by Celal Bayar University Scientific Research Project Unit (2002/085)

Teşekkür

Dear Editor; I have uploaded my work to your journal for evaluation. Kind regards

Kaynakça

  • Barkovich J (1996). Congenital anomalies of the spine. In Pediatric Neuroimaging (2nd ed., pp. 477–540). Lippincott Williams & Wilkins.
  • Canaz H, Erdoğan ET, Alataş B (2018). The results of ıntraoperative direct electrical stimulation of roots and placode during myelomeningocele repair. Kocaeli Tıp Dergisi, 7(3), 208–213.
  • Ertekin C (2006). Central and peripheral EMG. In Central and Peripheral EMG (1.baskı, pp. 912–932). Hipokrat Yayınevi.
  • Groppa S, Oliviero A, Eisen A, Quartarone A, Cohen L, Mall V et al (2012). A practical guide to diagnostic transcranial magnetic stimulation: Report of an IFCN committee. Clinical Neurophysiology, 123(5), 858–882.
  • Halevi PD, Udayakumaran S, Ben-Sira L, Constantini S. (2011). The value of postoperative MR in tethered cord: a review of 140 cases. Child’s Nervous System, 27(12), 2159–2162.
  • Hall WA, Albright A, Brunberg JA. (1988). Diagnosis of tethered cords by magnetic resonance imaging. Surgical Neurology, 30(1), 60–64.
  • Harreveld AV, Schadé JP (1962). Nerve cell destruction by asphyxiation of the spinal cord. Journal of Neuropathology and Experimental Neurology, 21(3),410–423.
  • Hoffman HJ, Hendrick B, Humphreys RP (1976). The tethered spinal cord: Its protean manifestations, diagnosis and surgical correction. Pediatric Neurosurgery, 2(3), 145–155.
  • Kobayashi M, Pascual-Leone A (2003). Transcranial magnetic stimulation in neurology. Lancet Neurology, 2(3), 145–156.
  • Koçak A, Kılıç A, Nurlu G, Konan A, Kılınç K, Çırak B, Çolak A (1997). A new model for tethered cord syndrome: a biochemical, electrophysiological, and electron microscopic study. Pediatric Neurosurgery, 26(3), 120–126.
  • Lefaucheur JP (2019). Transcranial magnetic stimulation. In Handbook of Clinical Neurology (pp. 559–580). Selçuki M (2011). Thick filum terminale. In Spinal Congenital Malformations: Turkıye Klinikleri Journal Neurosurg Special Topics.4(1) 44–49.
  • Menezes AH, Seaman SC, Howard MA, Hitchon PW, Takacs EB (2021). Tethered spinal cord syndrome in adults in the MRI era: recognition, pathology, and long-term objective outcomes. Journal of Neurosurgery Spine, 34(6), 942–954.
  • Oh S (2003). Clinical electromyography nerve conduction studies, 3rd edn. European Journal of Neurology, 10(5), 605.
  • Polo A, Zanette G, Manganotti P, Bertolasi L, De Grandis D, Rizzuto N (1994). Spinal somatosensory evoked potentials in patients with tethered cord syndrome. Canadian Journal of Neurological Sciences, 21(4), 325–330.
  • Ross J, Moore K, Shah L (2010). Diagnostic Imaging. In Diagnostic Imaging- Spine (2nd ed., pp. 128–131). Amirsys. Schneider SJ, Rosenthal AD, Greenberg BM, Danto J (1993). A preliminary report on the use of laser-doppler flowmetry during tethered spinal cord release. Neurosurgery/Neurosurgery Online, 32(2), 214–218.
  • Seçil Y, Ekinci AS, Bayram KB, İncesu TK, Tokuçoğlu F, Gürgör N et al (2012). Diagnostic value of cauda equina motor conduction time in lumbar spinal stenosis. Clinical Neurophysiology, 123(9), 1831–1835.
  • Selçuki M, Vatansever S, Inan S, Erdemli E, Bağdatoğlu C, Polat A (2003). Is a filum terminale with a normal appearance really normal? Child’s Nervous System, 19(1), 3–10.
  • Umur AS, Selcuki M, Selcuki D, Bedük A, Doganay L (2007). Adult tethered cord syndrome mimicking lumbar disc disease. Child’s Nervous System, 24(7), 841–844. Warder DE, Oakes WJ (1993). Tethered cord syndrome and the conus in a normal position. Neurosurgery/Neurosurgery Online, 33(3), 374–378.
  • Yamada S, Won D, Kido DK (2001). Adult tethered cord syndrome: new classification correlated with symptomatology, ımaging and pathophysiology. Neurosurgery Quarterly, 11(4), 260–275.
  • Yamada S, Zinke DE, Sanders D (1981). Pathophysiology of “tethered cord syndrome.” Journal of Neurosurgery, 54(4), 494–503.

Gergin Omurilik Sendromlu Hastalarda Preop ve Postop Motor Uyarılmış Potansiyel, Elektrofizyolojik İletim Çalışmaları, Nörolojik Muayene ve Lumbosakral MRG Tetkiklerinin Karşılaştırılması

Yıl 2025, Cilt: 18 Sayı: 2, 116 - 122, 30.08.2025
https://doi.org/10.52976/vansaglik.1695373

Öz

Gergin Omurilik sendromu (GOS), yetişkinlerde özellikle MRG öncesi dönemde sıklıkla gözden kaçan ilerleyici bir nörolojik bozukluktur. Bununla birlikte, elektrofizyolojik çalışmaların cerrahinin sonucunu belirlemede herhangi bir değeri olup olmadığı veya takipteki faydası hala bilinmemektedir. Bu çalışmada, GOS tanısı alan olgularda ameliyat öncesi motor uyarılmış potansiyellerin (MUP) cerrahi tedaviye yanıtı öngörme potansiyelini ve ameliyat sonrası MUP değerlerinin değişimini tanımlamayı amaçladık.

Proje Numarası

The Ethical Committee of the University of Celal Bayar approved the study (2012/118). Our study was financially supported by Celal Bayar University Scientific Research Project Unit (2002/085)

Kaynakça

  • Barkovich J (1996). Congenital anomalies of the spine. In Pediatric Neuroimaging (2nd ed., pp. 477–540). Lippincott Williams & Wilkins.
  • Canaz H, Erdoğan ET, Alataş B (2018). The results of ıntraoperative direct electrical stimulation of roots and placode during myelomeningocele repair. Kocaeli Tıp Dergisi, 7(3), 208–213.
  • Ertekin C (2006). Central and peripheral EMG. In Central and Peripheral EMG (1.baskı, pp. 912–932). Hipokrat Yayınevi.
  • Groppa S, Oliviero A, Eisen A, Quartarone A, Cohen L, Mall V et al (2012). A practical guide to diagnostic transcranial magnetic stimulation: Report of an IFCN committee. Clinical Neurophysiology, 123(5), 858–882.
  • Halevi PD, Udayakumaran S, Ben-Sira L, Constantini S. (2011). The value of postoperative MR in tethered cord: a review of 140 cases. Child’s Nervous System, 27(12), 2159–2162.
  • Hall WA, Albright A, Brunberg JA. (1988). Diagnosis of tethered cords by magnetic resonance imaging. Surgical Neurology, 30(1), 60–64.
  • Harreveld AV, Schadé JP (1962). Nerve cell destruction by asphyxiation of the spinal cord. Journal of Neuropathology and Experimental Neurology, 21(3),410–423.
  • Hoffman HJ, Hendrick B, Humphreys RP (1976). The tethered spinal cord: Its protean manifestations, diagnosis and surgical correction. Pediatric Neurosurgery, 2(3), 145–155.
  • Kobayashi M, Pascual-Leone A (2003). Transcranial magnetic stimulation in neurology. Lancet Neurology, 2(3), 145–156.
  • Koçak A, Kılıç A, Nurlu G, Konan A, Kılınç K, Çırak B, Çolak A (1997). A new model for tethered cord syndrome: a biochemical, electrophysiological, and electron microscopic study. Pediatric Neurosurgery, 26(3), 120–126.
  • Lefaucheur JP (2019). Transcranial magnetic stimulation. In Handbook of Clinical Neurology (pp. 559–580). Selçuki M (2011). Thick filum terminale. In Spinal Congenital Malformations: Turkıye Klinikleri Journal Neurosurg Special Topics.4(1) 44–49.
  • Menezes AH, Seaman SC, Howard MA, Hitchon PW, Takacs EB (2021). Tethered spinal cord syndrome in adults in the MRI era: recognition, pathology, and long-term objective outcomes. Journal of Neurosurgery Spine, 34(6), 942–954.
  • Oh S (2003). Clinical electromyography nerve conduction studies, 3rd edn. European Journal of Neurology, 10(5), 605.
  • Polo A, Zanette G, Manganotti P, Bertolasi L, De Grandis D, Rizzuto N (1994). Spinal somatosensory evoked potentials in patients with tethered cord syndrome. Canadian Journal of Neurological Sciences, 21(4), 325–330.
  • Ross J, Moore K, Shah L (2010). Diagnostic Imaging. In Diagnostic Imaging- Spine (2nd ed., pp. 128–131). Amirsys. Schneider SJ, Rosenthal AD, Greenberg BM, Danto J (1993). A preliminary report on the use of laser-doppler flowmetry during tethered spinal cord release. Neurosurgery/Neurosurgery Online, 32(2), 214–218.
  • Seçil Y, Ekinci AS, Bayram KB, İncesu TK, Tokuçoğlu F, Gürgör N et al (2012). Diagnostic value of cauda equina motor conduction time in lumbar spinal stenosis. Clinical Neurophysiology, 123(9), 1831–1835.
  • Selçuki M, Vatansever S, Inan S, Erdemli E, Bağdatoğlu C, Polat A (2003). Is a filum terminale with a normal appearance really normal? Child’s Nervous System, 19(1), 3–10.
  • Umur AS, Selcuki M, Selcuki D, Bedük A, Doganay L (2007). Adult tethered cord syndrome mimicking lumbar disc disease. Child’s Nervous System, 24(7), 841–844. Warder DE, Oakes WJ (1993). Tethered cord syndrome and the conus in a normal position. Neurosurgery/Neurosurgery Online, 33(3), 374–378.
  • Yamada S, Won D, Kido DK (2001). Adult tethered cord syndrome: new classification correlated with symptomatology, ımaging and pathophysiology. Neurosurgery Quarterly, 11(4), 260–275.
  • Yamada S, Zinke DE, Sanders D (1981). Pathophysiology of “tethered cord syndrome.” Journal of Neurosurgery, 54(4), 494–503.
Toplam 20 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Beyin ve Sinir Cerrahisi (Nöroşirurji), Nöroloji ve Nöromüsküler Hastalıklar
Bölüm Orijinal Araştırma Makaleleri
Yazarlar

Ümmü Serpil Sarı 0000-0001-5303-3621

Mehmet Selçuki 0000-0002-2310-3016

Deniz Selçuki 0000-0002-0518-7404

Gülgün Ovalı 0000-0001-8433-5622

Proje Numarası The Ethical Committee of the University of Celal Bayar approved the study (2012/118). Our study was financially supported by Celal Bayar University Scientific Research Project Unit (2002/085)
Erken Görünüm Tarihi 30 Ağustos 2025
Yayımlanma Tarihi 30 Ağustos 2025
Gönderilme Tarihi 8 Mayıs 2025
Kabul Tarihi 7 Ağustos 2025
Yayımlandığı Sayı Yıl 2025 Cilt: 18 Sayı: 2

Kaynak Göster

APA Sarı, Ü. S., Selçuki, M., Selçuki, D., Ovalı, G. (2025). Pre-Operational and Post-Operational Motor Stimulated Potential, Electrophysiological Conduction Studies in Patients with Tethered Cord Syndrome, Neurological Examination and Comparison of Lumbosacral MRG Investigations. Van Sağlık Bilimleri Dergisi, 18(2), 116-122. https://doi.org/10.52976/vansaglik.1695373

ISSN 

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