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AFLATOXIN ENTERING OUR LIVES WITH FEED AND FOOD AND PREVENTION METHODS

Year 2021, Volume: 12 Issue: 2, 105 - 117, 11.09.2021

Fadime Tonbak , Pelin Demir

https://doi.org/10.38137/vftd.966325

Abstract

Aflatoxins are fungal metabolites found in feeds and foods. Among mycotoxins, the aflatoxin group has received much attention due to its serious effects on human and animal health. When ruminants eat feed containing Aflatoxin B1 (AFB1), this toxin is metabolized and passed into milk as Aflatoxin M1 (AFM1). In recent years, AFB1 and AFM1 have been frequently mentioned in the correlation between toxin exposure and cancer cell proliferation and invasion. Recently, some epidemiological studies have been conducted to evaluate the effects of aflatoxin on cancer cells. This review summarizes of some data reported in the literature on the activation states of AFB1 and AFM1 and their correlation with cancer development.

Keywords

AFB1 AFM1 Aflatoxin Cancer Milk

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YEM VE GIDALARLA HAYATIMIZA GİREN AFLATOKSİNLERİ ÖNLEME YÖNTEMLERİ

Year 2021, Volume: 12 Issue: 2, 105 - 117, 11.09.2021

Fadime Tonbak , Pelin Demir

https://doi.org/10.38137/vftd.966325

Abstract

Aflatoksinler, yemlerde ve gıdalarda bulunan mantar metabolitleridir. Mikotoksinler arasında, aflatoksin grubu insan ve hayvan sağlığı üzerine ciddi etkileri nedeniyle çok dikkat çekmiştir. Geviş getiren hayvanlar Aflatoksin B1 (AFB1) içeren yemleri yediğinde, bu toksin metabolize olur ve Aflatoksin M1 (AFM1) olarak süte geçer. Son yıllarda, toksin maruziyeti ile kanser hücresi proliferasyonu ve invazyonu arasındaki korelasyonda AFB1 ve AFM1’den sıkça söz edilmektedir. Son zamanlarda kanser hücreleri üzerindeki aflatoksin etkilerini değerlendirmeyi amaçlayan bazı epidemiyolojik çalışmalar yapılmıştır. Bu derlemede, AFB1 ve AFM1’in aktivasyon durumları ve literatürde kanser gelişimiyle ilgili korelasyon hakkında rapor edilmiş olan bazı veriler özetlenmektedir.

Keywords

AFB1 AFM1 Kanser Süt

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Details

Primary Language Turkish
Subjects Veterinary Sciences
Journal Section Review
Authors

Fadime Tonbak 0000-0001-7308-512X

Pelin Demir 0000-0002-0824-1672

Publication Date September 11, 2021
Acceptance Date August 30, 2021
Published in Issue Year 2021 Volume: 12 Issue: 2

Cite

APA Tonbak, F., & Demir, P. (2021). YEM VE GIDALARLA HAYATIMIZA GİREN AFLATOKSİNLERİ ÖNLEME YÖNTEMLERİ. Veteriner Farmakoloji Ve Toksikoloji Derneği Bülteni, 12(2), 105-117. https://doi.org/10.38137/vftd.966325
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