Parvoviral enteritisli köpeklerde sepsis ve SİYS’e bağlı miyokardiyal fonksiyon değişikliklerinin ekokardiyografik değerlendirilmesi

Abstract

Bu çalışmada, parvoviral enteritisli köpeklerde sepsis ve SİYS'e bağlı miyokardiyal fonksiyon değişiklikleri ile standart ekokardiyografi ve iki boyutlu benek takibi ekokardiyografi (2DBTE) yöntemlerinin etkinliği karşılaştırılmıştır. Bulguların, kardiyak komplikasyonların erken teşhisine katkı sağlaması amaçlanmıştır. Çalışmaya, CPV enfeksiyonu teşhisi konulan ve SİYS kriterlerinden en az ikisini gösteren 16 yavru köpek (Grup A) ile sağlıklı 16 yavru köpek (Grup B) dâhil edildi. Grup A ve Grup B’de bulunan köpeklerden bir kez kan alınarak hematolojik muayene gerçekleştirildi. Her iki gruptaki yavru köpeklere standart ekokardiyografi ve 2DBTE uygulandı. 2DBTE ile sol ventrikül radyal gerilimi ve gerilim hızını belirlemek için görüntüler kaydedildi ve çevrimdışı analiz edildi. Grup A ve Grup B’nin radyal gerilim ve gerilim hızları kıyaslandığında istatistiksel olarak anlamlı bir farka rastlanmadı. Ancak Grup A’da ölen hayvanların sağlıklı hayvanlara kıyasla daha düşük radyal gerilim değerlerine sahip olduğu belirlendi. Standart ekokardiyografi ile belirlenen ejeksiyon fraksiyonunun (EF) ve fraksiyonel kısalmanın (FS) gruplar arasında fark oluşturmadığı görüldü. Sepsis ve SİYS görülen parvoviral enteritisli yavru köpeklerde sol ventrikül fonksiyonlarının etkilendiği ve bu fonksiyonların değerlendirilmesinde standart ekokardiyografi ile 2DBTE metodunun da kullanılması gerektiği kanısına varıldı.

Keywords

• benek takibi ekokardiyografi
• sepsis
• SİYS
• köpek parvovirus

Echocardiographic evaluation of myocardial function changes due to sepsis and SIRS in dogs with parvoviral enteritis

Abstract

In this study, the effectiveness of conventional echocardiography and two-dimensional speckle tracking echocardiography (2DSTE) methods were compared with changes in myocardial function due to sepsis and SIRS in dogs with parvoviral enteritis. The findings are aimed to contribute to the early diagnosis of cardiac complications. The study included 16 puppies diagnosed with CPV infection and meeting at least two of the SIRS criteria (Group A) and 16 healthy puppies (Group B). Blood sample was taken once from the dogs in Group A and Group B, and whole blood analysis was performed. Standard echocardiography and 2DSTE were performed to the puppies in both groups. Images were recorded and analyzed offline to determine left ventricular radial strain and strain rate with 2DSTE.When the radial strain and strain rate of Group A and Group B were compared, no statistically significant difference was found. However, it was determined that animals that died in Group A had lower radial strain values compared to healthy animals. Ejection fraction (EF) and fractional shortening (FS) determined by standard echocardiography did not differ between the groups. It was concluded that left ventricular functions are affected in puppies with parvoviral enteritis with sepsis and SIRS, and the 2DSTE method should be used together with standard echocardiography in the evaluation of these functions.

Keywords

• canine parvovirus
• sepsis
• SIRS
• speckle tracking echocardiography

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