The association of serum glucose and BHB levels, body condition score, calving type, season and parity with uterine health in Holstein dairy cows

Year 2019, Volume: 90 Issue: 2, 83 - 91, 15.06.2019

Hatice Esra Çolakoğlu , Murat Onur Yazlık

https://doi.org/10.33188/vetheder.517127

Abstract

The objective of current study was to evaluate the association of uterine health between serum glucose and beta hydroxybutyric acid (BHB) levels, body condition score (BCS), calving type (eutocia or dystocia), calving season (summer or winter) and parity in Holstein dairy cows and to determine the cut-off levels for these parameters. While cows without any reproductive problems during calving and pp 50 days enrolled into control group (n:27), cows with metritis and endometritis in the same days included the other one (n:33). BCS were recorded at dry period (-60 days), calving and pp 30 days. Blood samples were collected at d 21±3 prepartum and d 15 and d 35 for determination of glucose and BHB levels. Parity, calving type and calving season of cows were recorded and their relationship with uterine health were evaluated. Receiver operating characteristics (ROC) curves for BHB, glucose and BCS were used to determine the cow-level thresholds for the development of uterine problems. In addition, pairwise comparisons of area under the curve (AUC) of ROC curves for the thresholds of glucose, BHB, BCS predicting uterine problems were determined. While the BHB concentration were higher, glucose concentration were lower at 21±3 days prepartum and 15 days postpartum in cows with uterine problems. Serum glucose and BHB concentrations at 21±3 days prepartum and 15 days were also the best predictor for the diagnosis of uterine problems. However, BCS had no significant effect on development of uterine problems. There were also no significant effect of parity, calving season and type on development of uterine problems. In conclusion, serum glucose and BHB concentrations were the risk factors for uterine problems but BCS had no significant role on development of uterine disorders.

Keywords

BHB, cow, glucose, uterine infection

Holstein ırkı sütçü ineklerde serum glikoz ve BHB düzeyleri, vücut kondisyon skoru, doğum şekli, mevsimi ve sayısının uterus sağlığıyla ilişkisi

Abstract

Sunulan çalışmada Holstein ırkı ineklerde uterus enfeksiyonlarının; doğum şekli, doğum mevsimi, doğum sayısı, vücut kondisyon skoru, serum BHB ve glikoz konsantrasyonu ile ilişkisinin değerlendirilmesi ve anılan parametreler için kritik eşik değerlerin belirlenmesi amaçlandı. Doğum ve postpartum 50 gün aralığında reprodüktif sorun yaşamayan inekler kontrol grubuna (n=27), anılan süre içinde metritis ve endometritis saptanan inekler de uterus problemli inekler grubuna (n=33) dahil edildi. Gruplara ait ineklerin vücut kondisyon skorları kuruya çıkarken (-60. gün), doğum zamanında ve postpartum 30. günde belirlendi. Prepartum 21. gün, postpartum 15. ve 35. günlerde kan glikoz ve BHB konsantrasyonları belirlendi. İneklerin doğum sayıları, doğum şekli ve doğum mevsimi bilgileri toplanarak uterus durumu ile ilişkisi araştırıldı. BHB, Glikoz ve VKS değerleri ROC analizi ile değerlendirilerek her bir örnekleme zamanındaki uterus enfeksiyonlarının varlığının tahmin edilmesi amacıyla kritik eşik değerler saptandı. Uterus problemli ineklerin prepartum 21. günde ve pp 15. günde kan serum BHB düzeylerinin daha yüksek, glikoz düzeylerinin ise daha düşük olduğu gözlendi. Ayrıca, serum BHB ve glikoz konsantrasyonlarının prepartum 21. günde ve postpartum 15. günde en iyi ön belirteç oldukları gözlendi. VKS’nin uterus problemleri üzerine herhangi bir etkisi saptanmadı. Ayrıca doğum sayısı, doğum mevsimi ve doğum tipinin de uterus enfeksiyonlarının gelişimine herhangi bir etkisinin olmadığı gözlemlendi. Sonuç olarak, serum glikoz ve BHB düzeylerinin uterus problemleri açısından birer risk faktörü olduğu, ancak VKS’nin uterus enfeksiyonlarının gelişiminde belirgin bir role sahip olmadığı gözlendi.

Keywords

BHB, Glikoz, İnek, uterus enfeksiyonu

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