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Papillon ırkı bir köpekte pilomatrikoma

Year 2020, Volume: 91 Issue: 2, 159 - 163, 15.06.2020
https://doi.org/10.33188/vetheder.687405

Abstract

Pilomatrikoma, köpeklerde nadir olarak karşılaşılan iyi huylu adneksiyal deri tümörüdür. Papillon ırkı 13 yaşlı dişi bir köpeğin sırt bölgesinden, Ankara Üniversitesi Veteriner Fakültesi Cerrahi Anabilim Dalı’nda, operasyonla alınan 3 adet kitle çalışmanın materyalini oluşturdu. Kitlenin oluşumu altı ay önce başladığı bildirildi. Ayrıntılı bir histopatolojik inceleme için, cerrahi olarak rezeke edilen tümörler Ankara Üniversitesi Veteriner Fakültesi Patoloji Anabilim Dalı’na gönderildi. Makroskobik olarak, üzerinde ülserli deri bulunan kitleler, 1x0,5x0,5 cm, 2x2x1 cm ve 1x1x1 cm çapındaydı. Elastik kıvamda olan kitlelerin kesit yüzleri sarı-kırmızımsı renkteydi. Mikroskobik incelemede, her üç kitlede, hayalet/ gölge hücre olarak tanımlanan hücreler ile çevrili subkutanöz yerleşimli kistik yapılar fark edildi. Ayrıca hayalet hücrelerin yüzeyinde keratin iplikçikleri dikkati çekti. Kistik yapı göstermesi; kalsifikasyon ve dev hücrelerine rastlanmamasından dolayı insan hekimliğinde kullanılan kronolojik sınıflandırmaya göre, incelenen bu pilomatrikoma tümörünün erken lezyonu olarak teşhis edilmiştir. Pilomatrikoma erken lezyonunun tanımlanmasının, köpek pilomatrikoma tümörlerinin histopatolojik olarak kategorize edilmesine katkı sağlayacağı düşünülmüştür.

References

  • 1. Abramo F, Pratesi F, Cantile C, Sozzi S, Poli A (1999): Survey of canine and feline follicular tumours and tumour –like lesions in central Italy. J Small Anim Pract, 40(10), 479-481.
  • 2. Beck A, Huber D, Scuric V, Benic M, Hohsteter M, Kuzir S (2016): A four year retrospective study of the prevelence of canine follicular tumours in Croatia. Vet Arh, 86(3), 453-466.
  • 3. Can A (2014): Kıl folikülü kök hücreleri ve intrafoliküler homeostaz. Türkderm-Deri Hastalıkları ve Frengi Arşivi, 48, 6-9.
  • 4. Carrol EE, Fossey SL, Mangus LM, Carsillo ME, Rush LJ, McLeod CG, Johnson TO (2010): Malignant pilomatricoma in 3 dogs. Vet Pathol, 47(5), 937-943.
  • 5. Chung JY, Do SH, Park SJ, Jeong KS (2010): Pilomatrixoma in a maltese dog. Lab Anim Res, 26(1), 117-120.
  • 6. Elverici E, Barça AN, Araz L, Yüksel E (2011): Erkek memesinde nadir bir kitle: Pilomatricoma. Meme Sağlık Derg, 7, 137-139.
  • 7. Milli ÜH, Hazıroğlu R (2000): Deri. 735-737. In: Milli ÜH, Hazıroğlu R (Ed), Veteriner Patoloji. Medipres, Ankara.
  • 8. Hendrick MJ, Mahaffey EA, Moore FM, Vos JH, Walder EJ (1998): Histological classification of mesenchmal tumors of skin and soft tissues of domestic animals (WHO International classification of tumors of domestic animals). American Registry of Pathology. USA, 1-64.
  • 9. Kajino Y, Yamaguchi A, Hashimato N, Matsuura A, Sato N, Kikuchi K (2001): β-Catenin gene mutation in human hair follicle – related tumors. Pathol Int, 51(7), 543-548.
  • 10. Lan MY, Lan MC, Ho CY, Li WY, Lin CZ (2003): Pilomatricoma of the head and neck. Arch Otolaryngol Head Neck Surg, 129(12), 1327-1330.
  • 11. Kaddu S, Soyer HP, Hödl S, Kerl H (1996): Morphological stages of pilomatricoma. Am J Dermatopathol, 18(4), 333-338.
  • 12. Turka E, Karaca I, Ortac R (2016): Giant pilomatrixoma of the arm: An unusual presentation in a child. Journal of Experimental & Clinical Medicine, 33(1), 41-43.

Pilomatricoma in a papillon dog

Year 2020, Volume: 91 Issue: 2, 159 - 163, 15.06.2020
https://doi.org/10.33188/vetheder.687405

Abstract

Pilomatricoma is a benign adnexal skin neoplasm uncommonly reported in dogs. Three nodules surgically removed from the back of a 13-year-old female papillon dog at the Surgery Department of Ankara University, Faculty of Veterinary Medicine, formed the material of this study. The mass formation started six months earlier. Surgically resected nodules were sent to the Pathology Department of Ankara University, Faculty of Veterinary Medicine, for a detailed histopathological examination. Grossly, the nodules were 1x0,5x0,5 cm; 2x2x1 cm and 1x1x1 cm in diameter and covered with ulcerated skin. The masses were elastic in consistency with yellow-reddish cut sections. Histopathological examination revealed subcutaneous cystic structures surrounded by ghost cells or shadow cells and containing keratin filaments on the surface in all the nodules. The tumor was diagnosed according to the pilomatricoma chronological staging method used in human medicine as an early stage of pilomatricoma due to the presence of cystic structures and the absence of calcification and giant cells. This study is thought to assist by the definition of early lesion of canine pilomatricoma to the histopathological classification of pilomatricomas in canine species.

References

  • 1. Abramo F, Pratesi F, Cantile C, Sozzi S, Poli A (1999): Survey of canine and feline follicular tumours and tumour –like lesions in central Italy. J Small Anim Pract, 40(10), 479-481.
  • 2. Beck A, Huber D, Scuric V, Benic M, Hohsteter M, Kuzir S (2016): A four year retrospective study of the prevelence of canine follicular tumours in Croatia. Vet Arh, 86(3), 453-466.
  • 3. Can A (2014): Kıl folikülü kök hücreleri ve intrafoliküler homeostaz. Türkderm-Deri Hastalıkları ve Frengi Arşivi, 48, 6-9.
  • 4. Carrol EE, Fossey SL, Mangus LM, Carsillo ME, Rush LJ, McLeod CG, Johnson TO (2010): Malignant pilomatricoma in 3 dogs. Vet Pathol, 47(5), 937-943.
  • 5. Chung JY, Do SH, Park SJ, Jeong KS (2010): Pilomatrixoma in a maltese dog. Lab Anim Res, 26(1), 117-120.
  • 6. Elverici E, Barça AN, Araz L, Yüksel E (2011): Erkek memesinde nadir bir kitle: Pilomatricoma. Meme Sağlık Derg, 7, 137-139.
  • 7. Milli ÜH, Hazıroğlu R (2000): Deri. 735-737. In: Milli ÜH, Hazıroğlu R (Ed), Veteriner Patoloji. Medipres, Ankara.
  • 8. Hendrick MJ, Mahaffey EA, Moore FM, Vos JH, Walder EJ (1998): Histological classification of mesenchmal tumors of skin and soft tissues of domestic animals (WHO International classification of tumors of domestic animals). American Registry of Pathology. USA, 1-64.
  • 9. Kajino Y, Yamaguchi A, Hashimato N, Matsuura A, Sato N, Kikuchi K (2001): β-Catenin gene mutation in human hair follicle – related tumors. Pathol Int, 51(7), 543-548.
  • 10. Lan MY, Lan MC, Ho CY, Li WY, Lin CZ (2003): Pilomatricoma of the head and neck. Arch Otolaryngol Head Neck Surg, 129(12), 1327-1330.
  • 11. Kaddu S, Soyer HP, Hödl S, Kerl H (1996): Morphological stages of pilomatricoma. Am J Dermatopathol, 18(4), 333-338.
  • 12. Turka E, Karaca I, Ortac R (2016): Giant pilomatrixoma of the arm: An unusual presentation in a child. Journal of Experimental & Clinical Medicine, 33(1), 41-43.
There are 12 citations in total.

Details

Primary Language English
Subjects Veterinary Surgery
Journal Section Case Report
Authors

Tuncer Kutlu 0000-0002-8771-1256

Yanad Monsef 0000-0002-4929-9395

İrem Ergin 0000-0003-2373-5133

Osman Kutsal 0000-0003-3599-6867

Publication Date June 15, 2020
Submission Date February 10, 2020
Acceptance Date February 17, 2020
Published in Issue Year 2020 Volume: 91 Issue: 2

Cite

Vancouver Kutlu T, Monsef Y, Ergin İ, Kutsal O. Pilomatricoma in a papillon dog. Vet Hekim Der Derg. 2020;91(2):159-63.

Veteriner Hekimler Derneği Dergisi (Journal of Turkish Veterinary Medical Society) is an open access publication, and the journal’s publication model is based on Budapest Access Initiative (BOAI) declaration. All published content is licensed under a Creative Commons CC BY-NC 4.0 license, available online and free of charge. Authors retain the copyright of their published work in Veteriner Hekimler Derneği Dergisi (Journal of Turkish Veterinary Medical Society). 

Veteriner Hekimler Derneği / Turkish Veterinary Medical Society