Clinical and Histopathological Findings in Elderly Breast Cancer Patients: Single Center Results

Year 2022, Volume: 3 Issue: 3, 188 - 194, 30.07.2022

Elbrus Zarbaliyev

Abstract

Aim: In the literature, there are clinical and histopathological differences in elderly breast cancer patients compared to younger patients. In our
study, we compared elderly breast cancer patients treated in our hospital
with younger patients in terms of clinical and histopathological features.
Material and Methods: In our study, the results of breast cancer patients
treated between 01.01.2018 and 31.07.2021, Sancaktepe Martyr Prof.
Dr. İlhan Varank Training and Research Hospital was evaluated retrospectively after the approval of the Ethics Committee dated 27/10/2021
and numbered 2021-1999. The clinical features, histopathological findings and surgical treatment methods of the patients were evaluated
from their personal files. The patients were evaluated by dividing them
into young and old patient groups, and 65 years was determined as the
threshold value for the separation of young and old patients.
Results: 142 female breast cancer patients were included in our study,
103 (72.53%) were younger than 65 years old and 39 (27.47%) were
older than 65 years old. The presence of co-morbid disease was significantly higher in the elderly patient group than in the younger patient
group (p=0.0001). It was observed that the diagnosis of breast cancer
was mostly made with clinical findings in both young and old patient
groups, routine breast screening remained in the background, and large
tumor size and lymph node positivity were encountered in both groups.
ER and PR receptor positive, luminal type A, grade II and III tumors
and invasive ductal carcinomas with Ki 67 >15% were detected in elderly patients. Compared to the younger patients in our study, papillary
carcinoma was significantly more common in elderly patients.
Among the surgical treatments applied to elderly patients, axillary sentinel lymph node sampling and breast-conserving surgical treatment
techniques were observed most frequently. Discussion and Conclusion: We believe that the importance of breast
cancer screening programs for young and old women should be increased and treatment protocols for older breast cancer patients should
be determined by taking into account geriatric risks

Keywords

Breast Cancer, Breast Cancer İn The Elderly, Breast Cancer Screening Program

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