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Sensory Sensitivity in Migraine without Aura Patients Is Correlated with The Duration of The Disease and Comorbid Anxiety

Year 2023, Volume: 4 Issue: 3, 90 - 95, 29.12.2023

Abstract

Introduction: Migraine is a neurological disorder characterized by many different sensory symptoms such as pain, visual disturbances, nausea, vomiting, dizziness, hypersensitivity to light, sound, and smell. Migraine patients can perceive some sensory signals as harmful and stressful due to differences in sensory processing. These signals can be a source of stress and anxiety for migraine patients. Related to these, the aim of our study was to examine the relationship between sensory profiles and pain characteristics and anxiety and depression findings in migraine patients.

Materials and Methods: A total of 28 female migraine patients were evaluated for pain characteristics, sensory modulation with the Sensory Profile Questionnaire, and anxiety and depression with the Hospital Anxiety and Depression Scale. In order to investigate the relationships between these variables, correlation analyses were conducted.

Results: Our results suggest that migraine patients may have sensory processing disorders due to differences in their sensory profiles. Sensory profile scores representing sensory processing of migraine patients were found to be different from norm values. Younger age at onset and longer duration of migraine are associated with sensory processing disorders. In addition, patients with higher sensory sensitivity and sensory avoidance have more anxiety.

Conclusion: Our study results will shed light on treatments that holistically address the physical, cognitive and emotional factors of migraine patients depending on the relationships between sensory processing, anxiety and depression states and pain characteristics.

References

  • 1. Rasmussen BK, Jensen R, Schroll M, Olesen J. Epidemiology of headache in a general population -a prevalence study. J Clin Epidemiol. 1991;44(11):1147– 1157. https://doi.org/10.1016/0895-4356(91)90147-2
  • 2. Boran HE, Bolay H, Gantenbein HA. R, Pohl H. Sensory processing and sensorimotor integration in migraine. In: Coppola G, Chen W-T, editors. Neurophysiology of the Migraine Brain. Cham, Switzerland: Springer; 2021. pp. 113-131. https://doi.org/10.1007/978-3-030-56538-1_9
  • 3. Ayres AJ. Sensory integration and learning disorders. Western Psychological Services; 1973. 294 p.
  • 4. Dunn W. The impact of sensory processing abilities on the daily lives of young children and their families: a conceptual model. Infants Young Child. 1997;9(4):23–35. https://doi.org/10.1097/00001163-199704000-00005
  • 5. Noseda R, Burstein R. Migraine pathophysiology: anatomy of the trigeminovascular pathway and associated neurological symptoms, cortical spreading depression, sensitization, and modulation of pain. Pain. 2013;154:S44–S53. https://doi.org/10.1016/j.pain.2013.07.021
  • 6. Kelman L, Tanis D. The relationship between migraine pain and other associated symptoms. Cephalalgia. 2006;26(5):548–553. https://doi.org/10.1111/j.1468-2982.2006.01075.x
  • 7. Goadsby PJ, Holland PR, Martins-Oliveira M, Hoffmann J, Schankin C, Akerman S. Pathophysiology of migraine: a disorder of sensory processing. Physiol Rev; 2017. https://doi.org/10.1152/physrev.00034.2015
  • 8. Schwedt TJ. Multisensory integration in migraine. Curr Opin Neurol. 2013;26(3):248. https://doi.org/10.1097/WCO.0b013e328360edb1
  • 9. Harriott AM, Schwedt TJ. Migraine is associated with altered processing of sensory stimuli. Curr Pain Headache Rep. 2014;18:1–7. https://doi.org/10.1007/s11916-014-0458-8
  • 10. Brown C, Dunn W. Adolescent/adult sensory profile. San Antonio, TX, USA;Pearson; 2002. https://doi.org/10.1037/t56705-000
  • 11. Bolay H, Ozge A, Saginc P, Orekici G, Uludüz D, Yalın O, et al. Gender influences headache characteristics with increasing age in migraine patients. Cephalalgia. 2015;35(9):792–800. https://doi.org/10.1177/0333102414559735
  • 12. Ertas M, Baykan B, Kocasoy Orhan E, Zarifoglu M, Karli N, Saip S, et al.One-year prevalence and the impact of migraine and tension-type headache in Turkey: a nationwide home-based study in adults. J Headache Pain. 2012;13(2):147–157. https://doi.org/10.1007/s10194-011-0414-5
  • 13. Brown C, Tollefson N, Dunn W, Cromwell R, Filion D. The adult sensory profile: Measuring patterns of sensory processing. Am J Occup Ther. 2001;55(1):75–82. https://doi.org/10.5014/ajot.55.1.75
  • 14. Aydın MŞ. Adolesan/yetişkin duyu profili anketi Türkçe uyarlamasının geçerlilik güvenilirlik çalışması; 2015.
  • 15. Zigmond AS, Snaith RP. The hospital anxiety and depression scale. Acta Psychiatr Scand. 1983;67(6):361–370. https://doi.org/10.1111/j.1600-0447.1983.tb09716.x
  • 16. Aydemir O. Hastane anksiyete ve depresyon olçeği Türkçe formunun geçerlilik ve güvenilirliği. Turk Psikiyatri Derg. 1997;8:187–280.
  • 17. Mainero C, Boshyan J, Hadjikhani N. Altered functional magnetic resonance imaging resting‐state connectivity in periaqueductal gray networks in migraine. Ann Neurol. 2011;70(5):838–845. https://doi.org/10.1002/ana.22537
  • 18. Dunn W, Brown C. Factor analysis on the Sensory Profile from a national sample of children without disabilities. Am J Occup Ther. 1997;51(7):490–495. https://doi.org/10.5014/ajot.51.7.490
  • 19. Metz AE, Boling D, DeVore A, Holladay H, Liao JF, Vlutch KV. Dunn’s model of sensory processing: an investigation of the axes of the four-quadrant model in healthy adults. Brain Sci. 2019;9(2):35. https://doi.org/10.3390/brainsci9020035
  • 20. Senkowski D, Höfle M, Engel AK. Crossmodal shaping of pain: a multisensory approach to nociception. Trends Cogn Sci. 2014;18(6):319–327. https://doi.org/10.1016/j.tics.2014.03.005
  • 21. Stewart WF, Bigal ME, Kolodner K, Dowson A, Liberman JN, Lipton RB. Familial risk of migraine. Variation by proband age at onset and headache severity. Neurology. 2006;66(3):344–348. https://doi.org/10.1212/01. wnl.0000196640.71600.00
  • 22. Smitherman TA, Burch R, Sheikh H, Loder E. The prevalence, impact, and treatment of migraine and severe headaches in the United States: a review of statistics from national surveillance studies. J Headache Pain. 2013;53(3):427–436. https://doi.org/10.1111/head.12074
  • 23. Zwart JA, Dyb G, Hagen K, Ødegård K, Dahl A, Bovim G, et al. Depression and anxiety disorders associated with headache frequency. The Nord‐Trøndelag health study. Eur J Neurol. 2003;10(2):147–152. https://doi.org/10.1046/j.1468-1331.2003.00551.x
  • 24. Sharma K, Remanan R, Singh S. Quality of life and psychiatric co‑morbidity in Indian migraine patients: A headache clinic sample. Neurol India. 2013;61(4):355. https://doi.org/10.4103/0028-3886.117584
  • 25. Price A, Sumner P, Powell G. Subjective sensory sensitivity and its relationship with anxiety in people with probable migraine. J Headache Pain. 2021;61(9):1342–1350. https://doi.org/10.1111/head.14219
  • 26. Engel-Yeger B, Dunn W. The relationship between sensory processing difficulties and anxiety level of healthy adults. Br J Occup Ther. 2011;74(5):210–216. https://doi.org/10.4276/030802211X13046730116407
  • 27. Rieke EF, Anderson D. Adolescent/Adult Sensory Profile and obsessivecompulsive disorder. Am J Occup Ther. 2009;63(2):138–145. https://doi.org/10.5014/ajot.63.2.138

Aurasız Migren Hastalarında Duyusal Hassasiyet, Hastalık Süresi ve Komorbid Anksiyete ile İlişkilidir

Year 2023, Volume: 4 Issue: 3, 90 - 95, 29.12.2023

Abstract

Giriş: Migren ağrı, görme bozuklukları, bulantı, kusma, baş dönmesi, ışığa, sese ve kokuya aşırı duyarlılık, ekstremitelerde veya yüzde karıncalanma ve uyuşma gibi duyusal semptomlarla karakterize nörolojik bir hastalıktır. Migren hastalarında, duyusal uyarıları zararlı ve stresli olarak algıladıkları için depresyon ve anksiyete bozuklukları yaşama olasılıkları daha yüksektir. Bunlara bağlı olarak çalışmamızın amacı migren hastalarında duyusal modülasyon, ağrı, anksiyete ve depresyon arasındaki ilişkiyi incelemektir.

Gereç ve Yöntemler: Toplam 28 kadın migren hastasının ağrı özellikleri, Adolesan/Yetişkin Duyu Profili Anketi ile duyusal modülasyonları ve Hastane Anksiyete ve Depresyon Ölçeği ile anksiyete ve depresyon durumları değerlendirildi. Bu değişkenler arasındaki ilişkiler korelasyon analizleri ile incelendi.

Bulgular: Sonuçlarımız, migren hastalarının duyusal profillerindeki farklılıklara bağlı olarak duyusal işlemleme bozukluklarına sahip olabileceğini göstermektedir. Migren hastalarının duyusal işlemlerini temsil eden duyusal profil skorlarının norm değerlerden farklı olduğu bulunmuştur. Daha genç başlangıç yaşı ve daha uzun migren süresi duyusal işlemleme bozuklukları ile ilişkilidir. Duyusal hassasiyeti ve duyusal kaçınması yüksek olanların anksiyeteleri daha fazladır.

Sonuç: Çalışma sonuçlarımız, duyusal işlemleme, anksiyete ve depresyon durumları ile ağrı özellikleri arasındaki ilişkilere bağlı olarak migren hastalarının fiziksel, bilişsel ve duygusal faktörlerini bütünsel olarak ele alan tedavilere ışık tutacaktır.

References

  • 1. Rasmussen BK, Jensen R, Schroll M, Olesen J. Epidemiology of headache in a general population -a prevalence study. J Clin Epidemiol. 1991;44(11):1147– 1157. https://doi.org/10.1016/0895-4356(91)90147-2
  • 2. Boran HE, Bolay H, Gantenbein HA. R, Pohl H. Sensory processing and sensorimotor integration in migraine. In: Coppola G, Chen W-T, editors. Neurophysiology of the Migraine Brain. Cham, Switzerland: Springer; 2021. pp. 113-131. https://doi.org/10.1007/978-3-030-56538-1_9
  • 3. Ayres AJ. Sensory integration and learning disorders. Western Psychological Services; 1973. 294 p.
  • 4. Dunn W. The impact of sensory processing abilities on the daily lives of young children and their families: a conceptual model. Infants Young Child. 1997;9(4):23–35. https://doi.org/10.1097/00001163-199704000-00005
  • 5. Noseda R, Burstein R. Migraine pathophysiology: anatomy of the trigeminovascular pathway and associated neurological symptoms, cortical spreading depression, sensitization, and modulation of pain. Pain. 2013;154:S44–S53. https://doi.org/10.1016/j.pain.2013.07.021
  • 6. Kelman L, Tanis D. The relationship between migraine pain and other associated symptoms. Cephalalgia. 2006;26(5):548–553. https://doi.org/10.1111/j.1468-2982.2006.01075.x
  • 7. Goadsby PJ, Holland PR, Martins-Oliveira M, Hoffmann J, Schankin C, Akerman S. Pathophysiology of migraine: a disorder of sensory processing. Physiol Rev; 2017. https://doi.org/10.1152/physrev.00034.2015
  • 8. Schwedt TJ. Multisensory integration in migraine. Curr Opin Neurol. 2013;26(3):248. https://doi.org/10.1097/WCO.0b013e328360edb1
  • 9. Harriott AM, Schwedt TJ. Migraine is associated with altered processing of sensory stimuli. Curr Pain Headache Rep. 2014;18:1–7. https://doi.org/10.1007/s11916-014-0458-8
  • 10. Brown C, Dunn W. Adolescent/adult sensory profile. San Antonio, TX, USA;Pearson; 2002. https://doi.org/10.1037/t56705-000
  • 11. Bolay H, Ozge A, Saginc P, Orekici G, Uludüz D, Yalın O, et al. Gender influences headache characteristics with increasing age in migraine patients. Cephalalgia. 2015;35(9):792–800. https://doi.org/10.1177/0333102414559735
  • 12. Ertas M, Baykan B, Kocasoy Orhan E, Zarifoglu M, Karli N, Saip S, et al.One-year prevalence and the impact of migraine and tension-type headache in Turkey: a nationwide home-based study in adults. J Headache Pain. 2012;13(2):147–157. https://doi.org/10.1007/s10194-011-0414-5
  • 13. Brown C, Tollefson N, Dunn W, Cromwell R, Filion D. The adult sensory profile: Measuring patterns of sensory processing. Am J Occup Ther. 2001;55(1):75–82. https://doi.org/10.5014/ajot.55.1.75
  • 14. Aydın MŞ. Adolesan/yetişkin duyu profili anketi Türkçe uyarlamasının geçerlilik güvenilirlik çalışması; 2015.
  • 15. Zigmond AS, Snaith RP. The hospital anxiety and depression scale. Acta Psychiatr Scand. 1983;67(6):361–370. https://doi.org/10.1111/j.1600-0447.1983.tb09716.x
  • 16. Aydemir O. Hastane anksiyete ve depresyon olçeği Türkçe formunun geçerlilik ve güvenilirliği. Turk Psikiyatri Derg. 1997;8:187–280.
  • 17. Mainero C, Boshyan J, Hadjikhani N. Altered functional magnetic resonance imaging resting‐state connectivity in periaqueductal gray networks in migraine. Ann Neurol. 2011;70(5):838–845. https://doi.org/10.1002/ana.22537
  • 18. Dunn W, Brown C. Factor analysis on the Sensory Profile from a national sample of children without disabilities. Am J Occup Ther. 1997;51(7):490–495. https://doi.org/10.5014/ajot.51.7.490
  • 19. Metz AE, Boling D, DeVore A, Holladay H, Liao JF, Vlutch KV. Dunn’s model of sensory processing: an investigation of the axes of the four-quadrant model in healthy adults. Brain Sci. 2019;9(2):35. https://doi.org/10.3390/brainsci9020035
  • 20. Senkowski D, Höfle M, Engel AK. Crossmodal shaping of pain: a multisensory approach to nociception. Trends Cogn Sci. 2014;18(6):319–327. https://doi.org/10.1016/j.tics.2014.03.005
  • 21. Stewart WF, Bigal ME, Kolodner K, Dowson A, Liberman JN, Lipton RB. Familial risk of migraine. Variation by proband age at onset and headache severity. Neurology. 2006;66(3):344–348. https://doi.org/10.1212/01. wnl.0000196640.71600.00
  • 22. Smitherman TA, Burch R, Sheikh H, Loder E. The prevalence, impact, and treatment of migraine and severe headaches in the United States: a review of statistics from national surveillance studies. J Headache Pain. 2013;53(3):427–436. https://doi.org/10.1111/head.12074
  • 23. Zwart JA, Dyb G, Hagen K, Ødegård K, Dahl A, Bovim G, et al. Depression and anxiety disorders associated with headache frequency. The Nord‐Trøndelag health study. Eur J Neurol. 2003;10(2):147–152. https://doi.org/10.1046/j.1468-1331.2003.00551.x
  • 24. Sharma K, Remanan R, Singh S. Quality of life and psychiatric co‑morbidity in Indian migraine patients: A headache clinic sample. Neurol India. 2013;61(4):355. https://doi.org/10.4103/0028-3886.117584
  • 25. Price A, Sumner P, Powell G. Subjective sensory sensitivity and its relationship with anxiety in people with probable migraine. J Headache Pain. 2021;61(9):1342–1350. https://doi.org/10.1111/head.14219
  • 26. Engel-Yeger B, Dunn W. The relationship between sensory processing difficulties and anxiety level of healthy adults. Br J Occup Ther. 2011;74(5):210–216. https://doi.org/10.4276/030802211X13046730116407
  • 27. Rieke EF, Anderson D. Adolescent/Adult Sensory Profile and obsessivecompulsive disorder. Am J Occup Ther. 2009;63(2):138–145. https://doi.org/10.5014/ajot.63.2.138
There are 27 citations in total.

Details

Primary Language English
Subjects Pain, Sensory Systems, Neurology and Neuromuscular Diseases
Journal Section Araştırma makalesi
Authors

Merve Sevgi İnce 0000-0002-7121-7210

İlkem Güzel 0000-0001-9994-0120

Merve Ceren Akgör 0000-0002-5169-2233

Meltem Bahcelıoglu 0000-0001-5279-3450

Hayrunnisa Bolay 0000-0002-3357-7733

Publication Date December 29, 2023
Submission Date November 29, 2023
Acceptance Date December 11, 2023
Published in Issue Year 2023 Volume: 4 Issue: 3

Cite

AMA İnce MS, Güzel İ, Akgör MC, Bahcelıoglu M, Bolay H. Sensory Sensitivity in Migraine without Aura Patients Is Correlated with The Duration of The Disease and Comorbid Anxiety. YIU Saglik Bil Derg. December 2023;4(3):90-95.