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Review of Arnebia euсhroma as a Potential Medicinal Plant Based on Phytochemistry and Pharmacological Activity

Year 2024, , 176 - 191, 31.03.2024
https://doi.org/10.29133/yyutbd.1306035

Abstract

Abstract: Arnebia euchroma, commonly known as "Pink Arnebia," is a plant from the Boraginaceae family found in Western and Central Asia. Traditionally, it has been used to treat respiratory, gastrointestinal, and dermatological ailments. Recent studies have highlighted its pharmacological properties and potential health advantages, resulting in increased interest in this plant. Pharmacognostic investigations have revealed the presence of various beneficial phytochemicals. Phytochemical studies have identified several bioactive compounds in A. euсhroma, such as eugormoside A, eugormoside B, scopoletin, and β-sitosterol, which exhibit diverse biological activities like antioxidant, antimicrobial, anticancer, and anti-ulcer effects. The therapeutic potential of these bioactive compounds suggests that A. euсhroma could be beneficial for a wide range of diseases. Pharmacological studies have validated the plant's healing properties, demonstrating its antimicrobial activity against various pathogens. Furthermore, A. euсhroma extracts possess antioxidant and anti-inflammatory properties that can potentially mitigate oxidative stress and inflammation-related diseases. Other pharmacological actions of A. euсhroma include wound healing, gastroprotective, hepatoprotective, and anti-diabetic effects. Overall, A. euсhroma exhibits promise as a medicinal plant with significant health benefits. However, further research is required to identify the active compounds responsible for its pharmacological activity and elucidate their primary mechanisms of action. Additionally, clinical studies are necessary to assess its safety and efficacy when used therapeutically. The primary objective of this review is to showcase the phytochemical composition and traditional ethnopharmacological applications of A. euchroma worldwide. The study examines previous research concerning this plant, laying the foundation for a forward-looking perspective on the potential future of A. euchroma.

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Year 2024, , 176 - 191, 31.03.2024
https://doi.org/10.29133/yyutbd.1306035

Abstract

References

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  • Cao, H., Zhang, W., Liu, D., Hou, M., Liu, S., He, W., Lin, J., & Shao, M. (2020). Identification, in vitro evaluation and modeling studies of the constituents from the roots of Arnebia euchroma for antitumor activity and STAT3 inhibition. Bioorganic Chemistry, 96, 103655. https://doi.org/10.1016/j.bioorg.2020.103655
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  • Dar, G. H., Bhagat, R. C., & Khan, M. A. (2002). Biodiversity of the Kashmir Himalaya. Valley Book.
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  • Gupta, K., Garg, S., Singh, J., & Kumar, M. (2014). Enhanced production of naphthoquinone metabolite (shikonin) from cell suspension culture of Arnebia sp. and it’s up-scaling through bioreactor. 3 Biotech, 4(3), 263–273. https://doi.org/10.1007/s13205-013-0149-x
  • Hosseini, A., Mirzaee, F., Davoodi, A., Jouybari, H. B., & Azadbakht, M. (2018). The traditional medicine aspects, biological activity and phytochemistry of Arnebia spp. Medical Glasnik, 15(1). https://doi.org/10.17392/926-18
  • Huang, G., Zhao, H. R., Meng, Q. Q., Zhang, Q. J., Dong, J. Y., Zhu, B. Q. (2018). Synthesis and biological evaluation of sulfur-containing shikonin oxime derivatives as potential antineoplastic agents. European Journal of Medicinal Chemistry, 143(1), 166-81.
  • Husain, A., Ahmad, I., & Khan, M. S. (2001). Anti-inflammatory, anti-ulcer and hepatoprotective activities of Arnebia euchroma. Journal of Ethnopharmacology, 75(2-3), 283-289.
  • Hussain, H., Krohn, K., & Ahmad, V. U. (2012). Naphthoquinone derivatives from A. euchroma with antibacterial and antifungal activities. Pharmaceutical Biology, 50(4), 489-493.
  • Hussain, S., Imran, M., Nadeem, M. (2019). Phytochemicals from various tissues of A. euсhroma and their bioactivities. Molecules, 24(7), 1315.
  • Israili, Z. H. (2009). Ethnopharmacological studies of indigenous medicinal plants of Sarban Hills, Abbottabad District, Pakistan. Journal of Ethnopharmacology, 122(2), 142-157.
  • Jain, S. C., Singh, B., & Jain, R. (2000). Arnebins and antimicrobial activities of Arnebia hispidissima DC. Cell cultures. Phytomedicine, 6(6), 474-476. https://doi.org/10.1016/S0944-7113(00)80077-X
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There are 84 citations in total.

Details

Primary Language English
Subjects Botany
Journal Section Articles
Authors

Urmat Kazybekov 0009-0006-4651-0534

Gülbübü Kurmanbekova 0000-0002-4340-0886

Fatih Törnük 0000-0002-7313-0207

Early Pub Date March 25, 2024
Publication Date March 31, 2024
Acceptance Date December 22, 2023
Published in Issue Year 2024

Cite

APA Kazybekov, U., Kurmanbekova, G., & Törnük, F. (2024). Review of Arnebia euсhroma as a Potential Medicinal Plant Based on Phytochemistry and Pharmacological Activity. Yuzuncu Yıl University Journal of Agricultural Sciences, 34(1), 176-191. https://doi.org/10.29133/yyutbd.1306035

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