Antimicrobial and Antioxidant effect of Ficaria verna Huds.

Year 2021, , 277 - 281, 30.06.2021

Şule İnci , Ayşe Eren , Sevda Kırbağ Ahmet İsmail Özkan

https://doi.org/10.29133/yyutbd.823401

Cited By: 3

Abstract

Ficaria verna Huds. is a plant belonging to the Ranunculaceae family, known as mole grass and celandine among the people. It is known to have anti-inflammatory and anti-haemorrhagic pharmaceutical effects. In this study, it was aimed to determine the antimicrobial effect of different concentrations of F. verna extracts obtained from methanol, ethanol and chloroform and the antioxidant activity of different concentrations of the extract obtained from methanol. In the results obtained, the best antimicrobial effect (17-20 mm) against Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Bacillus megaterium, Salmonella thypii and Candida albicans was determined in the methanol extract of F. verna at a concentration of 1000 µg. It was observed that the scavenging effect of the DPPH radical of F. verna increased depending on increasing concentrations.

Keywords

Antimicrobial effect, Antioxidant effect, Ranunculus ficaria, Medical plant.

Ficaria verna Huds.’nin Antimikrobiyal ve Antioksidan Etkisi

Abstract

Ficaria verna Huds. halk arasında köstebek otu ve kırlangıç otu adıyla bilinen ve Ranunculaceae familyasına ait bir bitkidir. Antienflamatuar ve antihemorajik gibi farmasötik etkilerinin olduğu bilinmektedir. Halk arasında hemoroide karşı kullanılmaktadır. Bu çalışmada F. verna’nın metanol, etanol ve kloroformdan elde edilen ekstraklarının farklı konsantrasyonlarının antimikrobiyal etkisi ile metanoldan elde edilen ekstresinin farklı konsantrasyonlarının antioksidan aktivitesinin belirlenmesi amaçlanmıştır. Elde edilen sonuçlarda F. verna’nın metanol ekstresi 1000 µg konsantrasonda Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Bacillus megaterium, Salmonella thypii ve Candida albicans’a karşı en iyi antimikrobiyal etki (17-20mm) göstermiştir. F. verna’nın DPPH radikalinin süpürücü etkisinin artan konsantrasyonlara bağlı arttığı gözlemlenmiştir.

Keywords

Antimikrobiyal etki, Antioksidan etki, Ranunculus ficaria, Tıbbi bitki.

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