Idiopathic calcinosis cutis of the vulva in an adult woman, a case report

Year 2015, , 109 - 111, 02.01.2016

Mustafa Gazi Uçar , Ceyhan Uğurluoğlu Fatih Şanlıkan

https://doi.org/10.16948/zktb.76516

Abstract

Calcinosis cutis is an uncommon entity defined as the deposition of amorphous calcium and phosphate salts under epidermis. Idiopathic calcinosis cutis occurs in the absence of any metabolic disorder or tissue damage. A 40-year-old multiparous female presented with vulvar nodular masses with discomfort during intercourse only. Physical examination revealed a yellowish colored non-tender, pedunculated nodules measuring approximately 3×1 cm in the left side of vulva. The mass localized between labia minora and labia majora was solid, surfaced with the white pigmentation, irregular, fixed and in sessile nature. Laboratory evaluation revealed normal serum calcium and phosphorus levels and all other laboratory values were within normal reference ranges. Total surgical excision of the mass was performed under general anesthesia. The histopathological diagnosis revealed a calcinosis cutis of the vulva and no recurrence was detected 12 months after the initial treatment. 

Keywords

Skin neoplasms, calcinosis, vulvar dise- ases

Yetişkin bir hastada idiyopatik vulvar kalsinozis, olgu sunumu

Abstract

Kalsinozis kutis epidermis altına çözünemeyen kalsiyum fosfat tuzlarının birikmesi ile oluşan nadir bir hastalıktır. İdiopatik form metabolik hastalık veya doku hasarı olmadan ortaya çıkar. Tek şikâyeti ilişki sırasında rahatsızlık hissi olan, 40 yaşında multipar hasta vulvar kitle şikâyeti ile başvurdu. Muayenede sol vulvar bölgede sarımsı renkte, ağrısız, yaklaşık 3x1 cm boyutlarında nodüler lezyon gözlendi. Kitle labium minör ile labium majus arasında lokalize, üzerinde yer yer beyaz pigmentasyon olan, irregüler sınırlı, sert, fikse ve sapsız vasıftaydı. Hastanın serum kalsiyum fosfat düzeyleri ve diğer bütün laboratuar testleri normal referans aralığındaydı.  Genel anestezi altında lezyon total eksize edildi. Histopatolojik inceleme sonucu vulvar kalsinozis kutis olarak gelen hastanın daha sonraki 12 aylık takiplerinde rekürrens gözlenmedi. 

Keywords

Deri neoplazmları, kalsinoz, vulvar hastalıklar

References

• - Alabaz D, Mungan N, Turgut M, Dalay C. Unusual idiopathic calcinosis cutis universalis in a child. Case Rep Dermatol 2009 28;1(1):16-22.
• - Bernardo BD, Huettner PC, Merritt DF, Ratts VS. Idiopathic calcinosis cutis presenting as labial lesions in children: Report of two cases with literature review. J Pediatr Adolesc Gynecol 1999;12(3):157–60.
• - Guermazi A, Grigoryan M, Cordoliani F, Kérob D: Unusually diffuse idiopathic calcinosis cutis. Clin Rheumatol 2007;26(2):268-70.
• - Pugashetti R, Shinkai K, Ruben BS, Grossman ME, Maldonado J, Fox LP. Calcium may preferentially deposit in areas of elastic tissue damage. J Am Acad Dermatol 2011;64(2):296–301.
• - Çalka Ö, Bilgili SG, Karadağ AS, Bulut G, Önder SG. [Idiopathic circumscripta calcinosis cutis of the fingers] Archives of the Turkish Dermatology & Venerology/Turkderm 2013; 47(2): 117-9.
• - Silva RS1, Miranda CV, Bressan AL, Fontenelle E, Scotelaro Mde F. Case for diagnosis. Idiopathic calcinosis. An Bras Dermatol 2010;85(3):393-5.
• - Aksoy HM, Ozdemir R, Karaaslan O, Tiftikcioglu YO, Oruç M, Koçer U. Incidental idiopathic calcinosis cutis in a rhytidectomy patient. Dermatol Surg 2004;30(8):1145–7.
• -Çoban YK, Aytekin AH, Aydin EN. Idiopathic calcinosis cutis of the vulva. Indian J Dermatol 2013;58(6):464-6. doi: 10.4103/0019-5154.119960.
• - Joo YH, Kwon IH, Huh CH, Park KC, Youn SW. A case of persistent subepidermal calcified nodule in an adult treated with CO2 laser. J Dermatol 2004;31(6):480–3.
• -Reiter N, El-Shabrawi L, Leinweber B, Berghold A, Aberer E.Calcinosis cutis. Part II. Treatment options. J Am Acad Dermatol 2011;65(1):15-22,quiz 23-24.