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The prevelance of adenomyosis at hysterectomy and associated factors

Year 2015, , 102 - 105, 02.01.2016
https://doi.org/10.16948/zktb.11649

Abstract

Objective: Adenomyosis is a entity characterized by the presence of endometrial glands and stroma embedded within the myometrium without apparent contact with the endo-myometrial junction. As the diagnosis of adenomyosis is based on histological examination, the condition is best described in women at the time of hysterectomy.

Material and Methods: We evaluated results of 109 hysterectomized patients retrospectively. Age, parity, menopausal status and indication of hysterectomy were compared between adenomyosis positive and negative patients according to histological findings. P value under 0.05 was considered statistically significant.

Results: The mean of age patients with adenomyosis were 55. Parity and abnormal uterine bleeding were associated factors with adenomyosis (p<0.05). 

Concluison: Our study demonstrated that the prevalence of adenomyosis at hysterectomy was 29.4%. Adenomyosis is more frequent among women reporting abnormal uterine bleeding and with high parity.

References

  • Ferenczy A. Pathophysiology of adenomyosis. Hum Reprod Update .1998;4(4):312–22.
  • Azziz R. Adenomyosis: current perspectives. Obstet Gynecol Clin North Am 1989; 16(1):221–35.
  • Hunter WC, Smith LL, Reiner WC. Uterine adenomyosis; incidence, symptoms, and pathology in 1,856 hysterectomies. Am J Obstet Gynecol 1947;53(4):663-8.
  • Weiss G, Maseelall P, Schott LL, Brockwell SE, Schocken M, Johnston JM. Adenomyosis a variant, not a disease? Evidence from hysterectomized menopausal women in the Study of Women’s Health Across the Nation (SWAN). Fertil Steril 2009;91:201–6.
  • Mounsey AL, Wilgus A, Slawson DC. Diagnosis and management of endometriosis. Am Fam Physician 2006; 74,594–600.
  • Tahlan A, Nanda A, Mohan H. Uterine adenomyoma: a clinicopathologic review of 26 cases and a review of the literature. Int. J.Gynecol. Pathol. 2006;25, 361–365.
  • Saremi A, Bahrami H, Salehian P, Hakak N, Pooladi A.Treatment of adenomyomectomy in women with severe uterine adenomyosis using a novel technique. Reprod Biomed Online 2014;28(6):753-60.
  • Taran FA, Wallwiener M, Kabashi D, Rothmund R, Rall K, Kraemer B, et al. Clinical characteristics indicating adenomyosis at the time of hysterectomy: a retrospective study in 291 patients. Arch Gynecol Obstet 2012;285(6):1571-6
  • Bergholt T, Eriksen L, Berendt N, Jacobsen M, Hertz JB Prevalence and risk factors of adenomyosis at hysterectomy. Hum Reprod 2001;16(11):2418-21.
  • Haas S, Acker D, Donahue C, Katz ME.Variation in hysterectomy rates across small geographic areas of Massachusetts. Am J Obstet Gynecol 1993;169(1):150-4.
  • Parazzini F, Mais V, Cipriani S, Busacca M, Venturini P; GISE. Determinants of adenomyosis in women who underwent hysterectomy for benign gynecological conditions: results from a prospective multicentric study in Italy. Eur J Obstet Gynecol Reprod Biol 2009;143(2):103-6
  • Parazzini FVP, Panazza S, Chatenoud L, Oldani S, Crosignani PG. Risk factors for adenomyosis. Hum Reprod 1997;12:1275–9.
  • Vercellini P, Vigano P, Somigliana E, Daguati R, Abbiati A, Fedele L. Adenomyosis: epidemiological factors. Best Pract Res Clin Obstet Gynaecol 2006;20:465–77.
  • Levgur M, Abadi MA, Tucker A. Adenomyosis: symptoms, histology, and pregnancy terminations. Obstet Gynecol 2000;95:688–91.
  • Olive DL, Franklin RR, Gratkins LV. The association between endometriosis and spontaneous abortion. A retrospective clinical study. J Reprod Med 1982;27:333–8.
  • Vercellini P, Parazzini F, Oldani S, et al. Adenomyosis at hysterectomy: a study on frequency distribution and patient characteristics. Hum Reprod 1995;10:1160–2.
  • Azziz R. Adenomyosis in pregnancy. A review. J Reprod Med 1986;31:224–7.
  • Merrill JA, Creasman WT. Disorders of the uterine corpus. In: Scott JR, Di Sala PJ, Hammond CB, et al., editors. Danforth’s obstetrics and gynecology. 6th ed., Philadelphia: Lippincott; 1990. p. 1023.
  • Taran FA, Weaver AL, Coddington CC, Stewart EA Understanding adenomyosis: a case control study. Fertil Steril 2010;94(4):1223–8.
  • Panganamamula UR, Harmanli OH, Isik-Akbay EF, Grotegut CA, Dandolu V, Gaughan JP. Is prior uterine surgery a risk factor for adenomyosis? Obstet Gynecol 2004;104:1034–8.
  • Takahashi K, Nagata H, Kitao M. Clinical usefulness of determination of estradiol level in the menstrual blood for patients with endometriosis. Nihon Sanka Fujinka Gakkai Zasshi 1989;41(11):1849-50.

Histerektomi olgularında adenomyosis prevelansı ve ilişkili faktörler

Year 2015, , 102 - 105, 02.01.2016
https://doi.org/10.16948/zktb.11649

Abstract

Giriş: Adenomyosis, endometrial gland ve stromanın endometriumla ilişkisiz bir şekilde myometrium içine gömülmesidir. Tanısı histolojik incelemeye dayandığı için, bu durum en iyi histerektomi materyallerinin incelenmesi ile belirlenmektedir. 

Gereç ve Yöntemler: Bu çalışmada histerektomi olmuş 109 hastanın sonuçları retrospektif olarak incelendi. Yaş, parite, menapozal durum ve histerektomi endikasyonları adenomyosis olan ve olmayan grup arasında karşılaştırıldı. P değerinin 0.05 altında olması istatistiksel olarak anlamlı kabul edildi. 

Bulgular: Adenomyosis olan olguların ortalama yaşı 55 idi. Parite ve anormal uterin kanama adenomyosis olan olgularda daha yüksek idi (p<0.05).

Sonuç: Bu çalışmada histerektomi materyallerindeki adenomyosis oranı % 29.4 olarak görüldü. Anormal uterin kanaması olan ve parite sayısı fazla olan olgularda adenomyosis oranı daha sık görülmüştür.

References

  • Ferenczy A. Pathophysiology of adenomyosis. Hum Reprod Update .1998;4(4):312–22.
  • Azziz R. Adenomyosis: current perspectives. Obstet Gynecol Clin North Am 1989; 16(1):221–35.
  • Hunter WC, Smith LL, Reiner WC. Uterine adenomyosis; incidence, symptoms, and pathology in 1,856 hysterectomies. Am J Obstet Gynecol 1947;53(4):663-8.
  • Weiss G, Maseelall P, Schott LL, Brockwell SE, Schocken M, Johnston JM. Adenomyosis a variant, not a disease? Evidence from hysterectomized menopausal women in the Study of Women’s Health Across the Nation (SWAN). Fertil Steril 2009;91:201–6.
  • Mounsey AL, Wilgus A, Slawson DC. Diagnosis and management of endometriosis. Am Fam Physician 2006; 74,594–600.
  • Tahlan A, Nanda A, Mohan H. Uterine adenomyoma: a clinicopathologic review of 26 cases and a review of the literature. Int. J.Gynecol. Pathol. 2006;25, 361–365.
  • Saremi A, Bahrami H, Salehian P, Hakak N, Pooladi A.Treatment of adenomyomectomy in women with severe uterine adenomyosis using a novel technique. Reprod Biomed Online 2014;28(6):753-60.
  • Taran FA, Wallwiener M, Kabashi D, Rothmund R, Rall K, Kraemer B, et al. Clinical characteristics indicating adenomyosis at the time of hysterectomy: a retrospective study in 291 patients. Arch Gynecol Obstet 2012;285(6):1571-6
  • Bergholt T, Eriksen L, Berendt N, Jacobsen M, Hertz JB Prevalence and risk factors of adenomyosis at hysterectomy. Hum Reprod 2001;16(11):2418-21.
  • Haas S, Acker D, Donahue C, Katz ME.Variation in hysterectomy rates across small geographic areas of Massachusetts. Am J Obstet Gynecol 1993;169(1):150-4.
  • Parazzini F, Mais V, Cipriani S, Busacca M, Venturini P; GISE. Determinants of adenomyosis in women who underwent hysterectomy for benign gynecological conditions: results from a prospective multicentric study in Italy. Eur J Obstet Gynecol Reprod Biol 2009;143(2):103-6
  • Parazzini FVP, Panazza S, Chatenoud L, Oldani S, Crosignani PG. Risk factors for adenomyosis. Hum Reprod 1997;12:1275–9.
  • Vercellini P, Vigano P, Somigliana E, Daguati R, Abbiati A, Fedele L. Adenomyosis: epidemiological factors. Best Pract Res Clin Obstet Gynaecol 2006;20:465–77.
  • Levgur M, Abadi MA, Tucker A. Adenomyosis: symptoms, histology, and pregnancy terminations. Obstet Gynecol 2000;95:688–91.
  • Olive DL, Franklin RR, Gratkins LV. The association between endometriosis and spontaneous abortion. A retrospective clinical study. J Reprod Med 1982;27:333–8.
  • Vercellini P, Parazzini F, Oldani S, et al. Adenomyosis at hysterectomy: a study on frequency distribution and patient characteristics. Hum Reprod 1995;10:1160–2.
  • Azziz R. Adenomyosis in pregnancy. A review. J Reprod Med 1986;31:224–7.
  • Merrill JA, Creasman WT. Disorders of the uterine corpus. In: Scott JR, Di Sala PJ, Hammond CB, et al., editors. Danforth’s obstetrics and gynecology. 6th ed., Philadelphia: Lippincott; 1990. p. 1023.
  • Taran FA, Weaver AL, Coddington CC, Stewart EA Understanding adenomyosis: a case control study. Fertil Steril 2010;94(4):1223–8.
  • Panganamamula UR, Harmanli OH, Isik-Akbay EF, Grotegut CA, Dandolu V, Gaughan JP. Is prior uterine surgery a risk factor for adenomyosis? Obstet Gynecol 2004;104:1034–8.
  • Takahashi K, Nagata H, Kitao M. Clinical usefulness of determination of estradiol level in the menstrual blood for patients with endometriosis. Nihon Sanka Fujinka Gakkai Zasshi 1989;41(11):1849-50.
There are 21 citations in total.

Details

Primary Language Turkish
Subjects Health Care Administration
Journal Section OBSTETRICS AND GYNECOLOGY
Authors

Mehmet Şentürk

Mehmet Budak This is me

Yusuf Çakmak

Ömer Durukan This is me

Mesut Polat

Publication Date January 2, 2016
Published in Issue Year 2015

Cite

APA Şentürk, M., Budak, M., Çakmak, Y., Durukan, Ö., et al. (2016). Histerektomi olgularında adenomyosis prevelansı ve ilişkili faktörler. Zeynep Kamil Tıp Bülteni, 46(4), 102-105. https://doi.org/10.16948/zktb.11649
AMA Şentürk M, Budak M, Çakmak Y, Durukan Ö, Polat M. Histerektomi olgularında adenomyosis prevelansı ve ilişkili faktörler. Zeynep Kamil Tıp Bülteni. January 2016;46(4):102-105. doi:10.16948/zktb.11649
Chicago Şentürk, Mehmet, Mehmet Budak, Yusuf Çakmak, Ömer Durukan, and Mesut Polat. “Histerektomi olgularında Adenomyosis Prevelansı Ve ilişkili faktörler”. Zeynep Kamil Tıp Bülteni 46, no. 4 (January 2016): 102-5. https://doi.org/10.16948/zktb.11649.
EndNote Şentürk M, Budak M, Çakmak Y, Durukan Ö, Polat M (January 1, 2016) Histerektomi olgularında adenomyosis prevelansı ve ilişkili faktörler. Zeynep Kamil Tıp Bülteni 46 4 102–105.
IEEE M. Şentürk, M. Budak, Y. Çakmak, Ö. Durukan, and M. Polat, “Histerektomi olgularında adenomyosis prevelansı ve ilişkili faktörler”, Zeynep Kamil Tıp Bülteni, vol. 46, no. 4, pp. 102–105, 2016, doi: 10.16948/zktb.11649.
ISNAD Şentürk, Mehmet et al. “Histerektomi olgularında Adenomyosis Prevelansı Ve ilişkili faktörler”. Zeynep Kamil Tıp Bülteni 46/4 (January 2016), 102-105. https://doi.org/10.16948/zktb.11649.
JAMA Şentürk M, Budak M, Çakmak Y, Durukan Ö, Polat M. Histerektomi olgularında adenomyosis prevelansı ve ilişkili faktörler. Zeynep Kamil Tıp Bülteni. 2016;46:102–105.
MLA Şentürk, Mehmet et al. “Histerektomi olgularında Adenomyosis Prevelansı Ve ilişkili faktörler”. Zeynep Kamil Tıp Bülteni, vol. 46, no. 4, 2016, pp. 102-5, doi:10.16948/zktb.11649.
Vancouver Şentürk M, Budak M, Çakmak Y, Durukan Ö, Polat M. Histerektomi olgularında adenomyosis prevelansı ve ilişkili faktörler. Zeynep Kamil Tıp Bülteni. 2016;46(4):102-5.