Comparison of outcomes of KOH/IUI and IVF treatment in advanced age infertile women

Abstract

Objective: The aim of the study was to compare the outcomes of patients >38 years of age who underwent COH/IUI and those who underwent IVF treatment.

Material and Method: 113 patients who meet the inclusion criteria were enrolled into the study. Of the 113 patients; 42 patients who underwent KOH/IUI and 71 patients who underwent IVF treatment. The biochemical, clinical and ongoing pregnancy rates were compared between two groups.

Results: There were significant differences in terms of biochemical and clinical pregnancy rates between two groups and those were higher in IVF treatment (p1=0.033, p2=0.031). Ongoing pregnancy rate was higher in IVF treatment group but there was no significant difference between two groups (p=0.084).

Conclusion: IVF treatment may be first line treatment option in advanced age women because of the higher success rates of IVF treatment than COH/IUI treatment.

Keywords

• In vitro fertilization
• intrauterine insemination
• advanced age

İleri yaş infertil kadınlarda KOS/IUI ile IVF tedavilerinin sonuçlarının karşılaştırılması

Abstract

Amaç: Çalışmada 38 yaş üzeri infertil kadınlarda KOS/IUI ile IVF tedavilerinin sonuçlarının karşılaştırılması amaçlanmaktadır.

Gereç ve Yöntem: 38 yaş üzerindeki KOS/IUI veya IVF tedavisi alan toplam 113 infertil kadın bu retrospektif çalışmaya dahil edilmiştir. Çalışmada KOS/IUI tedavisi uygulanmış 42 hasta, IVF tedavisi uygulanmış 71 hasta bulunmaktadır. İki grup biyokimyasal gebelik, klinik gebelik ve devam eden gebelik sonuçları açısından karşılaştırıldı.

Bulgular: İki grup arasında biyokimyasal gebelik ve klinik gebelik oranları arasında istatistiksel olarak anlamlı düzeyde farklılık saptandı. Biyokimyasal gebelik ve klinik gebelik oranları IVF tedavisi alan grupta daha yüksekti (p1=0.033, p2=0.031). Devam eden gebelik oranı IVF tedavisi alan grupta daha yüksek olmasına rağmen iki grup arasında istatistiksel derecede anlamlı bir fark saptanmadı (p=0.084).

Sonuç: İleri yaş grubundaki hastalarda IVF tedavisi KOS/IUI tedavisinden daha etkin olması nedeniyle bu yaş grubundaki hastalarda ilk tedavi seçeneği olarak IVF tedavisinin uygulanabileceğini düşünmekteyiz.

Keywords

• in vitro fertilization
• intrauterine inseminasyon
• ileri yaş

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