Analgesic effect of oral Hyoscine N Butyl Bromur in endometrial biopsy

Year 2019, , 187 - 189, 15.12.2019

Yesim Akdemir , Görker Sel Büşra Aynalı Müge Harma Mehmet İbrahim Harma

https://doi.org/10.16948/zktipb.622227

Abstract

Objective: To
investigate the efficacy of oral 10 mg Hyoscine N Butyl Bromur (HBB) on pain
perception of the patients who underwent endometrial biopsy with Pipelle.

Material and Method: The
charts of the patients who were 18-49 years and underwent endometrial biopsy with Pipelle for evaluation of
abnormal uterine bleeding at xxxxxxxxxxxxxxxxxxxxxxxxxxxxx between September 2018
and September 2019 were retrospectively evaluated. 48 patients were seperated as
HBB Group who used oral 10 mg HBB 30 minutes before endometrial biopsy and 56
patients as Control Group who did not used any pain relief medication before endometrial
biopsy.  

Results: There
were no statistically significant difference between two groups in age, BMI,
parity, number of vaginal and cesarean births, nulliparity, multipartiy, and
menopausal status. On the other hand, VAS (0) scores which were recorded
immediately after endometrial biopsy and VAS (30) scores which were recorded 30
minutes after endometrial biopsy of the patients of the HBB Group were lower
than the Control Group (59,3 ± 21,12 vs 86,42 ± 10.95, ve 19,09 ± 23,85 vs
55,71 ± 21,67 respectively; p≤0,001).

Conclusion: 10
mg oral HBB when taken 30 minutes before intervention, significantly decreases
pain associated with Pipelle endometrial biopsy. This data might help to
increase the endication spectrum of HBB for analgesic purposes in gynecology
field.

Keywords

Endometrial biopsy, Hyoscine N Butyl Bromur, pain, pipelle

Endometriyal biopsi işlemi öncesinde kullanılan oral Hyosine N Butil Bromur’ün analjezik etkinliği

Abstract

Amaç: Bu
çalışmanın amacı Pipelle ile yapılan endometrial biyopsi işlemi öncesinde oral
yoldan alınan 10 mg Hyosine N Butil Bromur (HBB)’nin analjezik etkinliğini
değerlendirmektir.

Gerek ve Yöntem: Eylül
2018- Eylül 2019 tarihleri arasında, xxxxxxxxxxxxx, anormal uterin kanamanın
değerlendirilmesi için Pipelle ile endometriyal biyopsi yapılmış, 18-49 yaş
arasındaki hastaların dosyaları retrospektif olarak incelendi. Endometriyal
biyopsi işleminin 30 dakika öncesinde oral yoldan 10 mg HBB kullanan 48
hasta HBB Grubu, endometriyal biyopsi işlemi öncesinde hiçbir analjezik
kullanmayan 56 hasta ise Kontrol Grubu olarak ayrıldı.

Bulgular: Yaş,
vücut kitle indeksi, parite, vajinal ve sezaryen doğum sayısı, nulliparite,
multiparite ve menopozal durum parametreleri açısından 2 grup arasında fark
gözükmezken endometriyal biyopsinin hemen sonrasında kaydedilmiş VAS (0) ve
endometriyal biyopsiden 30 dakika sonra kaydedilmiş olan VAS (30) skorları HBB
Grubunda Kontrol Grubuna göre daha düşük saptandı (sırasıyla 59,3 ± 21,12 vs
86,42 ± 10.95, ve 19,09 ± 23,85 vs 55,71 ± 21,67; p≤0,001)

Sonuç: Endometriyal
biyopsi işleminden 30 dakika önce oral yoldan alınan 10 mg HBB’nin,
endometriyal biyopsi sırasında ve işlemden 30 dakika sonrasında analjezik
etkinliği vardır. Bu data HBB’nin diğer jinekolojik endikasyonlar ile
kullanımının yaygınlaşmasına yardımcı olabilir.

Keywords

Ağrı, Hyosine N Butil Bromur, Pipelle, endometriyal biyopsi

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