Abstract
Lipoleiomyomatosis (LPL) is a rare benign tumor composed of fat and smooth muscle. Intravenous LPL is a rare subtype of intravenous leiomyomatosis (IVL). Although LPL is considered to be a benign lesion, IVL recurs in approximately 10% of reported cases, and must be distinguished from low-grade endometrial stromal sarcoma and leiomyosarcoma with vascular invasion. We report a case of intravenous LPL in the light of literature as a diagnostic challenge.
References
- 1) Honoré LH. Uterine fibrolipoleiomyoma: report of a case with discussion of histogenesis. Am J Obstet Gynecol 1978;132(6):635-6. 2) Sieiński W. Lipomatous neometaplasia of the uterus. Report of 11 cases with discussion of histogenesis and pathogenesis. Int J Gynecol Pathol 1989;8(4)357-63. 3) Aung T, Goto M, Nomoto M, et al. Uterine lipoleiomyoma: a histopathological review of 17 cases. Pathol Int 2004;54(10):751-8. 4) Akay HT, Ayhan H, Sezgin A. Succesfull Two Staged Surgical Treatment of Intravenous Leiomyoma with Intracardiac Extension: Case Report. Turkish
- Journal of Vascular Surgery 2013;22(1):142-5. 5) To WW, Ngan HY, Collins RJ. Intravenous leiomyomatosis with intracardiac involvement. Int J Gynaecol Obstet 1993;42(1):37-40. 6) Eren S, Yıldırım G, Kır G, Tuğrul S, Çilesiz P. İntravenöz Leiomyomatozis: Bir Olgu Sunumu Nedeniyle İzlem Protokolünün İrdelenmesi. Artemis 2004;5(2):147-9. 7) Kurman RJ ed. Blaustesin’s Pathology of the Female Genital Tract. 5.ed. Springer-Verlag, New York, 1994. 8) Devaney K, Tavassoli FA. Immunohistochemistry as a diagnostic aid in the interpretation of unusual mesenchymal tumors of the uterus. Mod Pathol 1991;4(2):225-31. 9) Kondi-Pafiti A, Graspa D, Kairi-Vassilatou E, et al. Mesenchymal tumors of the uterine corpus with heterologous and hematopoietic components: a study of ten cases and review of the literature. Eur J Gynaecol Oncol 2006;27(1):73-7. 10) Gentile R, Zarri M, De Lucchi F, et al. Lipoleiomyoma of the uterus. Pathologica 1996;88(2):132-4. 11) Pedeutour F, Quade BJ, Sornberger K, et al. Dysregulation of HMGIC in a uterine lipoleiomyoma with a complex rearrangement including chromosomes 7, 12, and 14. Genes Chromosomes Cancer 2000;27(2):209-15. 12) Hisaoka M, Sheng WQ, Tanaka A, Hashimoto H. HMGIC alterations in smooth muscle tumors of soft tissues and other sites. Cancer Genet Cytogenet. 2002;138(1):50-5. 13) Robert J, Brescia MD, Henry D, et al. Intravascular lipoleiomyomatosis: a report of two cases. Hum Pathol 1989;20(3):252-6. 14) Oliva E, Young RH, Clement PB, et al. Cellular benign mesenchymal tumors of the uterus. A comparative morphologic and immunohistochemical analysis of 33 highly cellular leiomyomas and six endometrial stromal nodules, two frequently confused tumors. Am J Surg Pathol 1995;19(7):757-68. 15) Vang R, Kempson RL. Perivascular epithelioid cell tumor (‘PEComa’) of the uterus: a subset of HMB-45-positive epithelioid mesenchymal neoplasms with an uncertain relationship to pure smooth muscle tumors. Am J Surg Pathol 2002;26(1):1-13. 16) Andrade LA, Torresan RZ, Sales JF Jr et al. Intravenous leiomyomatosus of the uterus: a report of three cases. Pathol Oncol Res1998;4(1):44-7. -115CiLT: 45 YIL: 2014 SAYI: 3
Uterusun İntravasküler Lipoleiomyomatozisi (Intravenous Lipoleiomyomatosis of Uterus: a Rare Subtype of Intravenous Leiomyomatosis)
Abstract
Lipoleiomyomatozis (LPL) dikkat çekici miktarda yağ dokusu içeren leiomyomlardır. Intravenöz LPL ise intravenöz leiomyomatozisin (IVL) nadir görülen bir alt tipidir. IVL benign bir lezyon olarak tanımlanmasına rağmen, IVL olarak bildirilen olguların %10'unda rekürrens saptanmıştır. Aynı zamanda mutlaka low-grade endometrial stromal sarkom ve vasküler invazyon yapan leiomyosarkomdan ayrımı yapılmalıdır. Hastanemizde myom nedeniyle opere edilmiş ve kliniğimizde myometriuma sınırlı intravenöz LPL tanısı alan olgumuzu literatür eşliğinde sunduk.
Anahtar kelimeler: intravasküler leiomyom, intravenöz lipoleiomyomatozis, leiomyom.
Abstract
Lipoleiomyomatosis (LPL) is a rare benign tumor composed of fat and smooth muscle. Intravenous LPL is a rare subtype of intravenous leiomyomatosis (IVL). Although LPL is considered to be a benign lesion, IVL recurs in approximately 10% of reported cases, and must be distinguished from low-grade endometrial stromal sarcoma and leiomyosarcoma with vascular invasion. We report a case of intravenous LPL in the light of literature as a diagnostic challenge.
Key words: intravenous leiomyomatosis, intravenous lipoleiomyomatosis, leiomyoma.
References
- 1) Honoré LH. Uterine fibrolipoleiomyoma: report of a case with discussion of histogenesis. Am J Obstet Gynecol 1978;132(6):635-6. 2) Sieiński W. Lipomatous neometaplasia of the uterus. Report of 11 cases with discussion of histogenesis and pathogenesis. Int J Gynecol Pathol 1989;8(4)357-63. 3) Aung T, Goto M, Nomoto M, et al. Uterine lipoleiomyoma: a histopathological review of 17 cases. Pathol Int 2004;54(10):751-8. 4) Akay HT, Ayhan H, Sezgin A. Succesfull Two Staged Surgical Treatment of Intravenous Leiomyoma with Intracardiac Extension: Case Report. Turkish
- Journal of Vascular Surgery 2013;22(1):142-5. 5) To WW, Ngan HY, Collins RJ. Intravenous leiomyomatosis with intracardiac involvement. Int J Gynaecol Obstet 1993;42(1):37-40. 6) Eren S, Yıldırım G, Kır G, Tuğrul S, Çilesiz P. İntravenöz Leiomyomatozis: Bir Olgu Sunumu Nedeniyle İzlem Protokolünün İrdelenmesi. Artemis 2004;5(2):147-9. 7) Kurman RJ ed. Blaustesin’s Pathology of the Female Genital Tract. 5.ed. Springer-Verlag, New York, 1994. 8) Devaney K, Tavassoli FA. Immunohistochemistry as a diagnostic aid in the interpretation of unusual mesenchymal tumors of the uterus. Mod Pathol 1991;4(2):225-31. 9) Kondi-Pafiti A, Graspa D, Kairi-Vassilatou E, et al. Mesenchymal tumors of the uterine corpus with heterologous and hematopoietic components: a study of ten cases and review of the literature. Eur J Gynaecol Oncol 2006;27(1):73-7. 10) Gentile R, Zarri M, De Lucchi F, et al. Lipoleiomyoma of the uterus. Pathologica 1996;88(2):132-4. 11) Pedeutour F, Quade BJ, Sornberger K, et al. Dysregulation of HMGIC in a uterine lipoleiomyoma with a complex rearrangement including chromosomes 7, 12, and 14. Genes Chromosomes Cancer 2000;27(2):209-15. 12) Hisaoka M, Sheng WQ, Tanaka A, Hashimoto H. HMGIC alterations in smooth muscle tumors of soft tissues and other sites. Cancer Genet Cytogenet. 2002;138(1):50-5. 13) Robert J, Brescia MD, Henry D, et al. Intravascular lipoleiomyomatosis: a report of two cases. Hum Pathol 1989;20(3):252-6. 14) Oliva E, Young RH, Clement PB, et al. Cellular benign mesenchymal tumors of the uterus. A comparative morphologic and immunohistochemical analysis of 33 highly cellular leiomyomas and six endometrial stromal nodules, two frequently confused tumors. Am J Surg Pathol 1995;19(7):757-68. 15) Vang R, Kempson RL. Perivascular epithelioid cell tumor (‘PEComa’) of the uterus: a subset of HMB-45-positive epithelioid mesenchymal neoplasms with an uncertain relationship to pure smooth muscle tumors. Am J Surg Pathol 2002;26(1):1-13. 16) Andrade LA, Torresan RZ, Sales JF Jr et al. Intravenous leiomyomatosus of the uterus: a report of three cases. Pathol Oncol Res1998;4(1):44-7. -115CiLT: 45 YIL: 2014 SAYI: 3
Details
| Primary Language | Turkish |
|---|---|
| Journal Section | Original Research |
| Authors | |
| Publication Date | August 6, 2014 |
| Published in Issue | Year 2014 Volume: 45 Issue: 3 |
