Fetal ventrikülomegalili olgularda prognoz ve etkileyen faktörlerin değerlendirilmesi

Nazan Tarhan; Bülent Tandoğan; Vedat Dayıcıoğlu

doi:10.16948/zktb.41116

Evaluation of pregnancy outconme and affecting factors in cases with ventriculomegaly

Year 2002, Volume: 33 Issue: 4, 44 - 47, 01.05.2002

Nazan Tarhan Bülent Tandoğan Vedat Dayıcıoğlu

Abstract

Objective: Evaluation of pregnancy outcome and affecting factors in cases with ventriculomegaly. Materials and Methods: In this prospective study, we investigated 54 fetuses with ventriculomegaly. We evaluated the difference in prognosis between isolated ventriculomegaly and ventriculomegaly with associated anomalies. Results: Twenty-four (44.4%) among 54 fetuses had isolated ventriculomegaly, rest of the cases (n=12 22.2%) had ventriculomegaly + spina bifida without other anomalies and 18 cases (33.4%) had ventriculomegaly with other anomalies. Termination of pregnancy was applied in 14 patients (26%) electively by the approval of family. There was only 1 (1.8%) antepartum death, and were 20 (37%) intra partum deaths, 15 (28%) neonatal deaths. Isolated ventriculomegaly number were 14 (26%) and ventriculomegaly with associated anomalies were 4 (7.4%) among alive 18 (33.2%) cases at the end of the study. In 3 cases (5.5%) ventriculo-peritoneal shunts were inserted. Clinically significant neurological deficit were found in 4 cases (7.4%). All cases that surgically intervened had ventriculomegaly with associated anomalies. Conclusion: Accompanying other anomalies worsen the outcome in patients with ventriculomegaly.

Keywords

Prospective Studies, Pregnancy, Prognosis, Abnormalities

References

1. Hertzberg BS, Lile R, Foosaner DE et al: Choroid plexus -ventricular wall separation in fetuses with normal-sized cerebral ventricles et sonography
Postnatal outcome. AJR Am J Roentgenol 63:405,1994
2. Cardoza JD, Goldstein RB, Filly RA Exclusion of fetal ventriculomegaly with a single measure-ment:The width of lateral ventricular atrium.AJR Am J Roentgenol 151:767,1988 3. Schwanitz G, Schuler H, Gembruch U ,Zerres KC: Chromosomal findings in fetuses with ultrasonographically diagnosed ventriculomegaly
Ann Genet 1993;36:150-153
4. Bronsteen RA, Comstock HC: Central Nervous system anomalies. Clin Perinat 2000;4:791-812
5. Chervenak FA, Duncan C, Ment LR et al: Outcome of fetal ventriculomegaly. Lancet 1984;2:179-181
6. Hudgins RJ, Michael SBE, Goldstein R et al: Natural history of Fetal Ventriculomegaly
Pediatrics 1988;5:692-697
7. Chervenak FA, Berkowitz RL, Tortora M, Hobbins JC: The Management of fetal hydrocephalus. Am J Obstet Gynecol 1985;151:933-942
8. Gupta JK, Bryce FC, Lilford RJ: Management of apparently isolated fetal ventriculomegaly. Obstet Gynecol Surv 1994;49:716-721
9. Oi S, Matsumoto S, Katayama K, Mochizuki M: Pathophysiology and postnatal outcome of fetal hydrocephalus. Childs Nerv Syst 1990 ;6:338-345
10. Hoppe-Hirsch E, Laroussinie F, Brunet L, Sainte-Rose C, Renier D, Cinalli G,. Late outcome of the surgical treatment of hydrocephalus. Childs Nerv Syst 1998 ;14:97-99
11. Jamjoom AB, Kahlaf NF, Mohammed AA, Jamjoom ZA: Factors affecting the outcome of foetal hydrocephaly. Acta Neurochir 1998;140:l 121-1125
12. Futagi Y, Suzuki Y, Toribe Y, Morimoto K.Neurodevelopmental outcome in children with fetal hydrocephalus.Pediatr Neurol 2002 ;27:111-116
13. Tomlinson MW, Treadwell MC, Bottoms SF isolated mild ventriculomegaly associated karyotypic abnormalities and in utero observationj Mater Fetal Med 1997,6:241-244
14. Mori K, Shimada J, Kurisaka M, Sato K, Watanabe K. Classification of hydrocepjialus and outcome of treatment 1995;17:338-348

Fetal ventrikülomegalili olgularda prognoz ve etkileyen faktörlerin değerlendirilmesi

Year 2002, Volume: 33 Issue: 4, 44 - 47, 01.05.2002

Nazan Tarhan Bülent Tandoğan Vedat Dayıcıoğlu

Abstract

Amaç: Ventrikülomegali tespit edilen fetuslarda gebelik sonuçlarının ve bunları etkileyen faktörlerin değerlendirilmesi. Materyal ve Metod: Bu prospektif çalışmada, ventrikülomegali tespit edilen 54 olguda gebelik sonuçlan ve izole ventrikülomegali ile eşlik eden anomali varlığında prognozdaki farklılık ortaya kon-maya çalışıldı. Bulgular: Olguların 24'ü (%44.4) izole ventrikülomegali, 12'si (%22.2) ventrikülomegali + spina bifidalı, 18'i (%33.4) ventrikülomegali + diğer anomalili (kombine) olgulardı. 14 olgu ailenin isteğiyle elektif olarak sonlandırıldı. Olguların l'i (%1.8) antepartum, 20'si (%37) intrapartum, 15'i (%28) neonatal dönemde kaybedildi. İzole olguların 14'ü (%26), kombine olguların 4'ü (%7.4) olmak üzere toplam 18 (%33.2) olgu çalışma bittiğinde yaşıyordu. Üç olguya (%5.5) ventriküloperitoneal şant uygulandı. Dört olguda (%7.4) nörolojik muayenede bulgu saptandı. Nörolojik bozukluk çıkan olguların hepsi kombine olgulardı. Sonuç: Ventrikülomegaliye diğer anomalilerin eşlik etmesi prognozu kötüleştirir.

Keywords

İleriye dönük çalışma, Gebelik, Seyir, Anomaliler

References

1. Hertzberg BS, Lile R, Foosaner DE et al: Choroid plexus -ventricular wall separation in fetuses with normal-sized cerebral ventricles et sonography
Postnatal outcome. AJR Am J Roentgenol 63:405,1994
2. Cardoza JD, Goldstein RB, Filly RA Exclusion of fetal ventriculomegaly with a single measure-ment:The width of lateral ventricular atrium.AJR Am J Roentgenol 151:767,1988 3. Schwanitz G, Schuler H, Gembruch U ,Zerres KC: Chromosomal findings in fetuses with ultrasonographically diagnosed ventriculomegaly
Ann Genet 1993;36:150-153
4. Bronsteen RA, Comstock HC: Central Nervous system anomalies. Clin Perinat 2000;4:791-812
5. Chervenak FA, Duncan C, Ment LR et al: Outcome of fetal ventriculomegaly. Lancet 1984;2:179-181
6. Hudgins RJ, Michael SBE, Goldstein R et al: Natural history of Fetal Ventriculomegaly
Pediatrics 1988;5:692-697
7. Chervenak FA, Berkowitz RL, Tortora M, Hobbins JC: The Management of fetal hydrocephalus. Am J Obstet Gynecol 1985;151:933-942
8. Gupta JK, Bryce FC, Lilford RJ: Management of apparently isolated fetal ventriculomegaly. Obstet Gynecol Surv 1994;49:716-721
9. Oi S, Matsumoto S, Katayama K, Mochizuki M: Pathophysiology and postnatal outcome of fetal hydrocephalus. Childs Nerv Syst 1990 ;6:338-345
10. Hoppe-Hirsch E, Laroussinie F, Brunet L, Sainte-Rose C, Renier D, Cinalli G,. Late outcome of the surgical treatment of hydrocephalus. Childs Nerv Syst 1998 ;14:97-99
11. Jamjoom AB, Kahlaf NF, Mohammed AA, Jamjoom ZA: Factors affecting the outcome of foetal hydrocephaly. Acta Neurochir 1998;140:l 121-1125
12. Futagi Y, Suzuki Y, Toribe Y, Morimoto K.Neurodevelopmental outcome in children with fetal hydrocephalus.Pediatr Neurol 2002 ;27:111-116
13. Tomlinson MW, Treadwell MC, Bottoms SF isolated mild ventriculomegaly associated karyotypic abnormalities and in utero observationj Mater Fetal Med 1997,6:241-244
14. Mori K, Shimada J, Kurisaka M, Sato K, Watanabe K. Classification of hydrocepjialus and outcome of treatment 1995;17:338-348

There are 16 citations in total.

Details

Primary Language	Turkish
Journal Section	Articles
Authors	Nazan Tarhan This is me Bülent Tandoğan This is me Vedat Dayıcıoğlu This is me
Publication Date	May 1, 2002
Published in Issue	Year 2002 Volume: 33 Issue: 4

Cite

APA	Tarhan, N., Tandoğan, B., & Dayıcıoğlu, V. (2002). Fetal ventrikülomegalili olgularda prognoz ve etkileyen faktörlerin değerlendirilmesi. Zeynep Kamil Tıp Bülteni, 33(4), 44-47. https://doi.org/10.16948/zktb.41116
AMA	Tarhan N, Tandoğan B, Dayıcıoğlu V. Fetal ventrikülomegalili olgularda prognoz ve etkileyen faktörlerin değerlendirilmesi. Zeynep Kamil Tıp Bülteni. May 2002;33(4):44-47. doi:10.16948/zktb.41116
Chicago	Tarhan, Nazan, Bülent Tandoğan, and Vedat Dayıcıoğlu. “Fetal ventrikülomegalili Olgularda Prognoz Ve Etkileyen faktörlerin değerlendirilmesi”. Zeynep Kamil Tıp Bülteni 33, no. 4 (May 2002): 44-47. https://doi.org/10.16948/zktb.41116.
EndNote	Tarhan N, Tandoğan B, Dayıcıoğlu V (May 1, 2002) Fetal ventrikülomegalili olgularda prognoz ve etkileyen faktörlerin değerlendirilmesi. Zeynep Kamil Tıp Bülteni 33 4 44–47.
IEEE	N. Tarhan, B. Tandoğan, and V. Dayıcıoğlu, “Fetal ventrikülomegalili olgularda prognoz ve etkileyen faktörlerin değerlendirilmesi”, Zeynep Kamil Tıp Bülteni, vol. 33, no. 4, pp. 44–47, 2002, doi: 10.16948/zktb.41116.
ISNAD	Tarhan, Nazan et al. “Fetal ventrikülomegalili Olgularda Prognoz Ve Etkileyen faktörlerin değerlendirilmesi”. Zeynep Kamil Tıp Bülteni 33/4 (May 2002), 44-47. https://doi.org/10.16948/zktb.41116.
JAMA	Tarhan N, Tandoğan B, Dayıcıoğlu V. Fetal ventrikülomegalili olgularda prognoz ve etkileyen faktörlerin değerlendirilmesi. Zeynep Kamil Tıp Bülteni. 2002;33:44–47.
MLA	Tarhan, Nazan et al. “Fetal ventrikülomegalili Olgularda Prognoz Ve Etkileyen faktörlerin değerlendirilmesi”. Zeynep Kamil Tıp Bülteni, vol. 33, no. 4, 2002, pp. 44-47, doi:10.16948/zktb.41116.
Vancouver	Tarhan N, Tandoğan B, Dayıcıoğlu V. Fetal ventrikülomegalili olgularda prognoz ve etkileyen faktörlerin değerlendirilmesi. Zeynep Kamil Tıp Bülteni. 2002;33(4):44-7.