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Evaluation of postmenopausal smears with regard to cervical intraepithelial neoplasia

Year 2004, Volume: 35 Issue: 3, 121 - 123, 01.04.2004

Abstract

Objective: To investigate the prevelance of CIN in postmenopausal women in our region. Material and Methods: Between 1997 and 2000 years, 12783 women who applied Menopause Clinic for taking hormone replacement therapy with or without complaints were retrospectively evaluated. Results: Of the 349 cases with abnormal smear findings, 265 were CIN I (%75.8 ), 40 were CIN II (%11.4 ), 6 were CIN III (%2), 2 were carsinoma insituf %0.6 )and 36 were koilocytosis (%10.2 ). General prevelance of abnormal cervical findings in this age group was determined aproximately % 3. Conclusios: Although in women of postmenopausal age early stage servical intraepithelial lesions is seen not rare, it is clearly that they must be evaluated for transformation zone even if they are asymptomatic.

References

  • 1. Disaia Creasman, Clinical gynecologic oncology. Sixth edition. 2002;1-4 2. Sebbelov AM, Kjorstad KE, Abeler VM, Norrild B. The prevalence of HPV type 16 and 18 DNA cervical cancer in different age groups: a study on the incidental cases of cervical cancer in Norway in 1983. gynecol Oncol. 1991:41:141-148
  • 3. Schneider A, Koutsky LA. Natural history and epidemiological features of genital HPV infection.In: Munoz N,Bosh FX,Shah KV, Meheus A,eds. The epidemiology of cervical cancer dnd human papillomavirus. Lyon: International Agency for Cancer Research, 1992;25-52
  • 4. Mandelblatt J, Schecter C, Fahs M, Muller C
  • Clinical implications of screening for cervical cancer under Medicare. The natural history of cervical cancer in the elderly: what do we know? What do we need to know? Am J Obstet Gynecol
  • 1991;164: 644-651
  • 5. Meijer CJL'M, van de Brule AJC, Snijders PJF, Helmefhorsi T, Kenemans P, Walboomers JMM
  • Detection of human papillomavirus in cervical scrapes by the polimerase chain reaction in relation to cytology: possible implications for cervical cancer screening. In: Munoz N, Bosh FX, Shsh KV, Meheus A, eds. The epidemiology of cervical cancer and human papillomavirus. Lyon: International Agency for Cancer Research. 1992;271-281
  • 6. Walton RI, Blanchet M, Boves DA et al. Cervical cancer screening programs. Can Med Assoc J. 1976; 114:1003-33
  • 7. Roberts AD, Denholm RB, CordinerJW. Cervical intraepithelial neoplasia in postmenopausal women with negative cervical cytology. Br Med J. 1985; 290:281
  • 8. Barron BA, Richard RM. Statistical model of the natural history of cervical carcinoma: estimate of the transition time from dyplasia to carcinoma insitu. J Natl Cancer Inst 1970; 45: 1025-30
  • 9. Gerbaldo D, Cristoforoni P, Leone M, Casciaro L, Baracchini P, Fulcheri E. The incidental finding of abnormal cervical histology in postmenopausal patients. Maturitas. 1995; 21:115-120

Postmenopozal smearlerin servikal intraepiteliyal neoplazi yönünden değerlendirilmesi

Year 2004, Volume: 35 Issue: 3, 121 - 123, 01.04.2004

Abstract

Amaç: Bölgemizdeki postmenopozal kadınlardaki CİNprevelansını göstermek amacıyla bir çalışma düzenledik. Materyal ve Metod: 1997 ve 2000 yıllan arasında menopoz polikliniğine HRT almak üzere başvuran 12783 hastapatoloji kayıtları incelenerek retrospektif olarak değerlendirilmiştir. Bulgular: 349 hastada anormal smear sonucu saptanmış olup bunların 265'i (%75.8) CİNİ, 4O'ı (%11.4) CİN II, 6 tanesi CİN III ( %2 ), 2 tanesi karsinoma insitu (% 0.6) ve 36 tanesi koilositozisdir (% 10.2 ) Bu yaş grubunda anormal servikal sitoloji genel prevelansı ise yaklaşık olarak %3 olarak belirlenmiştir. Sonuç: Postmenopozal dönemde erken dönem servikal intraepiteliyal lezyonlarm hiç de azımsanmayacak boyutlarda olması nedeniyle asemptomatik de olsa postmenopozal hastaların transformasyon zonu açısından değerlendirilmesi gerekliliği oldukça açıktır.

References

  • 1. Disaia Creasman, Clinical gynecologic oncology. Sixth edition. 2002;1-4 2. Sebbelov AM, Kjorstad KE, Abeler VM, Norrild B. The prevalence of HPV type 16 and 18 DNA cervical cancer in different age groups: a study on the incidental cases of cervical cancer in Norway in 1983. gynecol Oncol. 1991:41:141-148
  • 3. Schneider A, Koutsky LA. Natural history and epidemiological features of genital HPV infection.In: Munoz N,Bosh FX,Shah KV, Meheus A,eds. The epidemiology of cervical cancer dnd human papillomavirus. Lyon: International Agency for Cancer Research, 1992;25-52
  • 4. Mandelblatt J, Schecter C, Fahs M, Muller C
  • Clinical implications of screening for cervical cancer under Medicare. The natural history of cervical cancer in the elderly: what do we know? What do we need to know? Am J Obstet Gynecol
  • 1991;164: 644-651
  • 5. Meijer CJL'M, van de Brule AJC, Snijders PJF, Helmefhorsi T, Kenemans P, Walboomers JMM
  • Detection of human papillomavirus in cervical scrapes by the polimerase chain reaction in relation to cytology: possible implications for cervical cancer screening. In: Munoz N, Bosh FX, Shsh KV, Meheus A, eds. The epidemiology of cervical cancer and human papillomavirus. Lyon: International Agency for Cancer Research. 1992;271-281
  • 6. Walton RI, Blanchet M, Boves DA et al. Cervical cancer screening programs. Can Med Assoc J. 1976; 114:1003-33
  • 7. Roberts AD, Denholm RB, CordinerJW. Cervical intraepithelial neoplasia in postmenopausal women with negative cervical cytology. Br Med J. 1985; 290:281
  • 8. Barron BA, Richard RM. Statistical model of the natural history of cervical carcinoma: estimate of the transition time from dyplasia to carcinoma insitu. J Natl Cancer Inst 1970; 45: 1025-30
  • 9. Gerbaldo D, Cristoforoni P, Leone M, Casciaro L, Baracchini P, Fulcheri E. The incidental finding of abnormal cervical histology in postmenopausal patients. Maturitas. 1995; 21:115-120
There are 11 citations in total.

Details

Primary Language Turkish
Journal Section Articles
Authors

Ceyhun Numanoğlu This is me

Nevin Altuncu Numanoğlu This is me

İbrahim Polat This is me

Ahmet Gül This is me

Onur Erol This is me

Ahmet Gülkılık This is me

Publication Date April 1, 2004
Published in Issue Year 2004 Volume: 35 Issue: 3

Cite

APA Numanoğlu, C., Numanoğlu, N. A., Polat, İ., Gül, A., et al. (2004). Postmenopozal smearlerin servikal intraepiteliyal neoplazi yönünden değerlendirilmesi. Zeynep Kamil Tıp Bülteni, 35(3), 121-123. https://doi.org/10.16948/zktb.99986
AMA Numanoğlu C, Numanoğlu NA, Polat İ, Gül A, Erol O, Gülkılık A. Postmenopozal smearlerin servikal intraepiteliyal neoplazi yönünden değerlendirilmesi. Zeynep Kamil Tıp Bülteni. April 2004;35(3):121-123. doi:10.16948/zktb.99986
Chicago Numanoğlu, Ceyhun, Nevin Altuncu Numanoğlu, İbrahim Polat, Ahmet Gül, Onur Erol, and Ahmet Gülkılık. “Postmenopozal Smearlerin Servikal Intraepiteliyal Neoplazi yönünden değerlendirilmesi”. Zeynep Kamil Tıp Bülteni 35, no. 3 (April 2004): 121-23. https://doi.org/10.16948/zktb.99986.
EndNote Numanoğlu C, Numanoğlu NA, Polat İ, Gül A, Erol O, Gülkılık A (April 1, 2004) Postmenopozal smearlerin servikal intraepiteliyal neoplazi yönünden değerlendirilmesi. Zeynep Kamil Tıp Bülteni 35 3 121–123.
IEEE C. Numanoğlu, N. A. Numanoğlu, İ. Polat, A. Gül, O. Erol, and A. Gülkılık, “Postmenopozal smearlerin servikal intraepiteliyal neoplazi yönünden değerlendirilmesi”, Zeynep Kamil Tıp Bülteni, vol. 35, no. 3, pp. 121–123, 2004, doi: 10.16948/zktb.99986.
ISNAD Numanoğlu, Ceyhun et al. “Postmenopozal Smearlerin Servikal Intraepiteliyal Neoplazi yönünden değerlendirilmesi”. Zeynep Kamil Tıp Bülteni 35/3 (April 2004), 121-123. https://doi.org/10.16948/zktb.99986.
JAMA Numanoğlu C, Numanoğlu NA, Polat İ, Gül A, Erol O, Gülkılık A. Postmenopozal smearlerin servikal intraepiteliyal neoplazi yönünden değerlendirilmesi. Zeynep Kamil Tıp Bülteni. 2004;35:121–123.
MLA Numanoğlu, Ceyhun et al. “Postmenopozal Smearlerin Servikal Intraepiteliyal Neoplazi yönünden değerlendirilmesi”. Zeynep Kamil Tıp Bülteni, vol. 35, no. 3, 2004, pp. 121-3, doi:10.16948/zktb.99986.
Vancouver Numanoğlu C, Numanoğlu NA, Polat İ, Gül A, Erol O, Gülkılık A. Postmenopozal smearlerin servikal intraepiteliyal neoplazi yönünden değerlendirilmesi. Zeynep Kamil Tıp Bülteni. 2004;35(3):121-3.