Tüberküloz menenjitli olgularımızın değerlendirilmesi

Sedat Öktem; Cem Deniz; Günnur Tokuç; Engin Tutar; Selda Ağzıkuru; Perran Boran

doi:10.16948/zktb.10503

Evaluation of our patients with tuberculous meningitis

Year 2004, Volume: 35 Issue: 4, 205 - 209, 01.05.2004

Sedat Öktem Cem Deniz Günnur Tokuç Engin Tutar Selda Ağzıkuru Perran Boran

Abstract

Objective: Tuberculous meningitis has the highest mortality and morbidity among all meningitis. We planned this study to evaluate the prognosis and the factors that effect the prognosis in our patients. Material and Methods: In this study we aimed to asses the 15 cases hospitalized for tuberculous meningitis in the Pediatric Clinic of Dr. Liitfi Kirdar Kartal Training and Research Hospital in the last 2 years, retrospectively. Results: Of the 15 cases; 11 (73,3 %) were female, 4 (26,7 %) were male (M/F:0,36). The ages were between 4 months and 14 years (mean: 5,4 ±4,5 years). The hospitalization time was between 1 and 60 days (mean: 31 ± 16 days). Only in 3 cases (20 %) BCG scar was found. In 11 cases (73 %) there was family history of tuberculosis; in 12 cases (80 %) PPD test was negative. Of the 15; 5 cases (33 %) died, 3 cases (20 %) didn't come to control examinations, 7 cases (47 %) had sequelae. Conclusion: Tuberculous meningitis is stil an important health problem in our country.

Keywords

Retrospective Studies, Tuberculosis, Meningeal, Child, Prognosis

References

1. Raviglione MC, Snider DE Jr, Kochi A. Global epidemiology of tuberculosis. Morbidity and mortality of a worldwide epidemic. JAMA 1995;273:220-226 2. Rieder HL, Snider DE Jr, Cauthen GM. Extra-pulmonary tuberculosis in the United States. Am Rev Respir Dis 1990;141:347-351
3. Weir MR, Thornton GE Extra-pulmonary tuberculosis. Experience of a community hospital and review of the literature. Am J Med 1985;79:467-478 4. Salazar GE, Schmitz TL, Cama R, Sheen P. Pulmonary tuberculosis in children in a developing country. Pediatrics 2001;108:448-53
5. Maltezou HC, Spyridis P, Kafetzis DA. Extra- pulmonary tuberculosis in children. Arch Dis Child 2000;83:342-6
6. SomerA, Yalçın I, Güler N, Salman N, Ones Ü. Çocukluk çağı tüberküloz menenjitinde klinik bulgular ve prognoz. Klinik Dergisi 1998; 11:10-4
7. SomerA, Öneş Ü, Güler N, Yalçın I, Salman N. Computerized cranial tomography findings in children with tuberculous meningitis. Arch Helen Med 1997; 14:442-5
8. Rehrman R.E., Kliegman R., Jenson H.B. Tuberculosis . Nelson Textbook of Pediatrics 16th editon W.B. Saunders Company, 2004; 958-972
9. Ahuja GK, Mohan KK, Prasad K. Diagnostic criteria for tuberculous meningitis, and their validation. Tubercle Lung Dis 1994;75:149-52
10. Juan CG. Central nervous system infections. Neurol Clin 1999; 17: 737-59
11. Starke JR, Smith HD. Tuberculosis. In: Feigin RD Cherry YD. Textbook of Pediatric Infectious Diseases. 4th ed. Philadelphia: WB. Saunders 1998: 1196-239
12. Starke JR. Resurgence of tuberculosis in children. Pediatr Pulmonol 1995;11(suppl):16-17
13. Smith S, Jacobs RF, Wilson CB. Immunobiology of childhood tuberculosis: a window on the ontogeny of cellular immunity. J Pediatr 1997;131:16-26 14. Snider DE Jr, Rieder HL, Combs D, et al. Tuberculosis in children. Pediatr Infect Dis J 1988 : 7:271-278 15. Salazar GE, Schmitz TL, Cama R, Sheen P. Pulmonary tuberculosis in children in a developing country. Pediatrics 2001; 108: 448-53
16. American Academy of Pediatrics. Tuberculosis. Red Book: Report of the Committee on Infectious Diseases.26th ed; 593-613
17. Yaramış A, Gürkan F, Elevli M, et al. Central nervous system tuberculosis in children: A review of 214 cases. Pediatrics 1998; 102: 5-9
18. Garg RK. Tuberculosis of the central nervous system. Postgrad Med J 1995; 75: 133-40
19. Bhargava S, Gupta AK, Tandon PN. Tuberculous meningitis: a CT study. Br J Radiol 1982; 55:189-93
20. Çivilibal M, Selçuk N, Aydınlı N, Deveci U, Emiroğlu H. Merkezi sinir sistemi tüberkülozu geçiren çocuklarda klinik, nöroradyolojik bulgular ve prognoz. Çocuk Dergisi 2002; 2: 22-28

Tüberküloz menenjitli olgularımızın değerlendirilmesi

Year 2004, Volume: 35 Issue: 4, 205 - 209, 01.05.2004

Sedat Öktem Cem Deniz Günnur Tokuç Engin Tutar Selda Ağzıkuru Perran Boran

Abstract

Amaç: Tüberküloz menenjit, menenjitler içerisinde mortalite ve morbiditesi en yüksek olanıdır. Takip ettiğimiz olguların prognozlarını ve etkileyen faktörleri irdelemek amacıyla bu çalışmayı yaptık. Materyal Metod: Dr. Lütfi Kırdar Kartal Eğitim ve Araştırma Hastanesi Çocuk Kliniğinde, son iki yılda tüberküloz menenjit tanısıyla yatırılıp tedavi edilen toplam 15 hastayı retrospektif olarak inceledik. Bulgular:Hastaların ll'i (% 73,3) kız, 4'ü (%26,7) erkek olup (E/K=0,36) yaşları 4 ay ile 14 yaş arasında (5,4 ± 4,5yaş) değişmekteydi.Yatış süreleri 1 gün ile 60 gün arasında (31 ± 16 gün) olup, sadece 3 olguda (% 20) BCG skarı mevcuttu. 11 olguda (% 73) ailede tüberküloz öyküsü saptandı.12 olgunun (% 80) PPD incelemeleri (-) idi. 5 olgu (% 33) kaybedildi, 3 olgu (% 20) takipten çıktı; 7 olgu ise sekelli olarak yaşamaktadır.

Keywords

Geriyedönük çalışma, Tüberküloz, meningeal, Çocuk, Seyir

References

1. Raviglione MC, Snider DE Jr, Kochi A. Global epidemiology of tuberculosis. Morbidity and mortality of a worldwide epidemic. JAMA 1995;273:220-226 2. Rieder HL, Snider DE Jr, Cauthen GM. Extra-pulmonary tuberculosis in the United States. Am Rev Respir Dis 1990;141:347-351
3. Weir MR, Thornton GE Extra-pulmonary tuberculosis. Experience of a community hospital and review of the literature. Am J Med 1985;79:467-478 4. Salazar GE, Schmitz TL, Cama R, Sheen P. Pulmonary tuberculosis in children in a developing country. Pediatrics 2001;108:448-53
5. Maltezou HC, Spyridis P, Kafetzis DA. Extra- pulmonary tuberculosis in children. Arch Dis Child 2000;83:342-6
6. SomerA, Yalçın I, Güler N, Salman N, Ones Ü. Çocukluk çağı tüberküloz menenjitinde klinik bulgular ve prognoz. Klinik Dergisi 1998; 11:10-4
7. SomerA, Öneş Ü, Güler N, Yalçın I, Salman N. Computerized cranial tomography findings in children with tuberculous meningitis. Arch Helen Med 1997; 14:442-5
8. Rehrman R.E., Kliegman R., Jenson H.B. Tuberculosis . Nelson Textbook of Pediatrics 16th editon W.B. Saunders Company, 2004; 958-972
9. Ahuja GK, Mohan KK, Prasad K. Diagnostic criteria for tuberculous meningitis, and their validation. Tubercle Lung Dis 1994;75:149-52
10. Juan CG. Central nervous system infections. Neurol Clin 1999; 17: 737-59
11. Starke JR, Smith HD. Tuberculosis. In: Feigin RD Cherry YD. Textbook of Pediatric Infectious Diseases. 4th ed. Philadelphia: WB. Saunders 1998: 1196-239
12. Starke JR. Resurgence of tuberculosis in children. Pediatr Pulmonol 1995;11(suppl):16-17
13. Smith S, Jacobs RF, Wilson CB. Immunobiology of childhood tuberculosis: a window on the ontogeny of cellular immunity. J Pediatr 1997;131:16-26 14. Snider DE Jr, Rieder HL, Combs D, et al. Tuberculosis in children. Pediatr Infect Dis J 1988 : 7:271-278 15. Salazar GE, Schmitz TL, Cama R, Sheen P. Pulmonary tuberculosis in children in a developing country. Pediatrics 2001; 108: 448-53
16. American Academy of Pediatrics. Tuberculosis. Red Book: Report of the Committee on Infectious Diseases.26th ed; 593-613
17. Yaramış A, Gürkan F, Elevli M, et al. Central nervous system tuberculosis in children: A review of 214 cases. Pediatrics 1998; 102: 5-9
18. Garg RK. Tuberculosis of the central nervous system. Postgrad Med J 1995; 75: 133-40
19. Bhargava S, Gupta AK, Tandon PN. Tuberculous meningitis: a CT study. Br J Radiol 1982; 55:189-93
20. Çivilibal M, Selçuk N, Aydınlı N, Deveci U, Emiroğlu H. Merkezi sinir sistemi tüberkülozu geçiren çocuklarda klinik, nöroradyolojik bulgular ve prognoz. Çocuk Dergisi 2002; 2: 22-28

There are 16 citations in total.

Details

Primary Language	Turkish
Journal Section	Articles
Authors	Sedat Öktem This is me Cem Deniz This is me Günnur Tokuç This is me Engin Tutar This is me Selda Ağzıkuru This is me Perran Boran This is me
Publication Date	May 1, 2004
Published in Issue	Year 2004 Volume: 35 Issue: 4

Cite

APA	Öktem, S., Deniz, C., Tokuç, G., Tutar, E., et al. (2004). Tüberküloz menenjitli olgularımızın değerlendirilmesi. Zeynep Kamil Tıp Bülteni, 35(4), 205-209. https://doi.org/10.16948/zktb.10503
AMA	Öktem S, Deniz C, Tokuç G, Tutar E, Ağzıkuru S, Boran P. Tüberküloz menenjitli olgularımızın değerlendirilmesi. Zeynep Kamil Tıp Bülteni. May 2004;35(4):205-209. doi:10.16948/zktb.10503
Chicago	Öktem, Sedat, Cem Deniz, Günnur Tokuç, Engin Tutar, Selda Ağzıkuru, and Perran Boran. “Tüberküloz Menenjitli olgularımızın değerlendirilmesi”. Zeynep Kamil Tıp Bülteni 35, no. 4 (May 2004): 205-9. https://doi.org/10.16948/zktb.10503.
EndNote	Öktem S, Deniz C, Tokuç G, Tutar E, Ağzıkuru S, Boran P (May 1, 2004) Tüberküloz menenjitli olgularımızın değerlendirilmesi. Zeynep Kamil Tıp Bülteni 35 4 205–209.
IEEE	S. Öktem, C. Deniz, G. Tokuç, E. Tutar, S. Ağzıkuru, and P. Boran, “Tüberküloz menenjitli olgularımızın değerlendirilmesi”, Zeynep Kamil Tıp Bülteni, vol. 35, no. 4, pp. 205–209, 2004, doi: 10.16948/zktb.10503.
ISNAD	Öktem, Sedat et al. “Tüberküloz Menenjitli olgularımızın değerlendirilmesi”. Zeynep Kamil Tıp Bülteni 35/4 (May 2004), 205-209. https://doi.org/10.16948/zktb.10503.
JAMA	Öktem S, Deniz C, Tokuç G, Tutar E, Ağzıkuru S, Boran P. Tüberküloz menenjitli olgularımızın değerlendirilmesi. Zeynep Kamil Tıp Bülteni. 2004;35:205–209.
MLA	Öktem, Sedat et al. “Tüberküloz Menenjitli olgularımızın değerlendirilmesi”. Zeynep Kamil Tıp Bülteni, vol. 35, no. 4, 2004, pp. 205-9, doi:10.16948/zktb.10503.
Vancouver	Öktem S, Deniz C, Tokuç G, Tutar E, Ağzıkuru S, Boran P. Tüberküloz menenjitli olgularımızın değerlendirilmesi. Zeynep Kamil Tıp Bülteni. 2004;35(4):205-9.