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Serum Beta hCG artış hızı gebeliğin ilk 8 haftasında sabit değil ve ikiz gebeler ile tekiz gebeliklerde farklıdır

Year 2006, Volume 37, Issue 2, 29 - 32, 01.03.2006

Abstract

Aim: To compare the increasement rate of serum fihCG levels during the first 8 weeks of gestation in singleton and twin pregnancies Materials and Methods: This study prospecüvely assessed serum fihCG levels in 155 singelton and 105 twin gestations conceived by ICSI-ET. Three consecutive blood samples were drawn on days 12,30 and 45 following ET. Lineer regression lines were plotted and the slope of the lines were compared for the rate of fihCG increase Results: Both groups were comparable in terms of maternal age and BML In both stages (days 12-30 and 30-45), the rate of _hCG increase in twin gestations was significantly higher than singletons. In addition, in all gestation groups, the rate is significantly lower in stage 2 compared to stage 1. Conclusion: fihCG secretion increasement during the first 8 weeks of gestation is not constant and gradually decreased in advanced stages, thus this rate is more pronounced in twins compared to singletons.

References

  • Medical research international and the society of assisted reproductive technology, American Fertility Society: In Vitro Fertilization/ Embryo Transfer in the United States: 1988 results from the national IVF-ET registry. Fertil Steril 1990;53:13 Ben-Rafael Z, Fatch M, Flickinger GL, Tureck R, Blasco L, Mastroianni L. Incidence of abortion in pregnancies after In Vitro Fertilization and Embryo Transfer. Obstet Gynecol 1988;71:297-300 Landy HJ, Weisher S, Larson S, Batzer FR, Bolognese RJ. The "Vanishing twin": ultrasonographic assessment of fetal disappearance in the first trimester. Am. J. Obstet. Gynecol. 1986;155:14 Kelly MD, Molo MW, Maclin VM,Binor Z, Rawlins RG,Rodwanska E. Human Chorionic Gonadotropin rise in normal and vanishing twin pregnancies. Fertil Steril 1991;56:221-4 Poikkeus P, Hiilesmaa V, Tiitinen A. Serum HCG 12 days after embryo transfer in predicting pregnancy outcome. Hum Reprod. 2002l;17:1901- 5 Mol BW, van der Veen F, Hajenius PJ, Engelsbel S, Ankum WM, Hogerzeil HV, Hemrika DJ, Bossuyt PM. Diagnosis of ectopic pregnancy after in vitro fertilization and embryo transfer. Fertil Steril
  • 1997;68:1027-32 Fritz MA, Gua S. Doubling time of human chorionic gonadotropin (hCG) in early normal pregnancy:relationship to hCG concentration and gestational age. Fertil Steril 1987;47:584-9 Pittaway DE, Reish RL, Wentz AC. Doubling times of human chorionic gonadotropin increase in early viable intrauterine pregnancies. Am J
  • Obstet Gynecol 1985;152:299-302 Daya S. Human chorionic gonadotropin increase in normal early pregnancy. Am J. Obstet Gynecol 1987;156:286-90 Urbancsek J, Hauzman E, Fedorcsak P, Halmos A, Devenyi N, Papp ZSerum human chorionic gonadotropin measurements may predict pregnancy outcome and multiple gestation after in vitro fertilization. Fertil Steril. 2002;78:540-2 Glatstein IZ, Hornstein MD, Kohana MJ, Jackson KV, Friedman AJ. The predictive value of discriminatory human chorionic gonadotropin levels in the diagnosis of implantation outcome in in vitro fertilization. Fertil Steril 1995;63:350- 56 Fridstorm M, Garaff L, Sjohlam P, Hillenjo T
  • Human chorionic gonadotropin patterns in early pregnancy after assisted reproduction. Acta Obstet Scand 1995;74:534-8 Schmidt LL, Asch RH, Frederick JL,Rojas FJ,Stone SC, Balmaceda JP. The predictive value of a single beta human chorionic gonadotropin in pregnancies achieved by assisted reproductive technology. Fertil Steril 1994;62:333-8 Dodson WC, Tyrey L,Haney AF. Serum human chorionic gonadotropin concentration for predicting multiple gestation in pregnancies conceived with superovulation and intrauterine insemination. J Reprod Med 1991;36:651-4 Keith SC,London SN, Weitzman GA, O'Brien TJ, Miller MM. Serial transvaginal ultrasound scans and b human chorionic gonadotropin levels in early singleton and multiple pregnancies. Fertil Steril.1993;59:1007-10 Liu HC, Kreiner B, Muasher SJ, Jones G, Jones Jr H, Rosenvaks Z. B human chorionic gonadotropin as a monitor of pregnancy outcome in in vitro fertilization-embryo transfer patients
  • Fertil Steril. 1998;50:89-94

The rate of increase in serum Beta hCG levels during the first 8 weeks of gestational life is not constatnt and different between singletons and twins

Year 2006, Volume 37, Issue 2, 29 - 32, 01.03.2006

Abstract

Serum fihCG Artış Hızı Gebeliğin İlk 8 Haftasında Sabit Değil Ve İkiz Gebeler İle Tekiz Gebeliklerde Farklıdır. Amaç: Serum fthCG değerindeki artış hızının gebeliğin ilk 8 haftasında değerlendirmek ve ikiz gebeler ile karşılaştırmak Materyal ve Metodlan Bu çalışma prospektif olarak ICSI-ET sonrası elde edilmiş 155 tekiz ve 105 ikiz gebede serum hcg değerlerini incelemiştir. Ardışık olarak her gebeden ET sonrası 12., 30. ve 45. günler serum fihCG seviyeleri saptanmış ve logaritmik olarak lineer regresyon analizi ile doğrular elde edilmiştir. Doğruların eğimi artış hızı olarak düşünülmüş ve farklar karşılaştırılmıştır. Bulgular: Her iki grup maternal yaş ve VKİ olarak benzerlikler göstermektedir. Her iki evrede de (12-30 günler ve 30-45 günler), ikiz gebelerdeki artış hızı tekizlere gore daha fazla saptanmıştır. Tüm gruplarda fihCG artış hızı ikinci evrede daha az olarak bulunmuştur. Sonuç: Gebeliğin ilk 8 haftasında fthCG sekresyon hızı sabit olmamakta ve ikiz gebelerde artış hızı tekiz gebelere gore daha fazla saptanmaktadır.

References

  • Medical research international and the society of assisted reproductive technology, American Fertility Society: In Vitro Fertilization/ Embryo Transfer in the United States: 1988 results from the national IVF-ET registry. Fertil Steril 1990;53:13 Ben-Rafael Z, Fatch M, Flickinger GL, Tureck R, Blasco L, Mastroianni L. Incidence of abortion in pregnancies after In Vitro Fertilization and Embryo Transfer. Obstet Gynecol 1988;71:297-300 Landy HJ, Weisher S, Larson S, Batzer FR, Bolognese RJ. The "Vanishing twin": ultrasonographic assessment of fetal disappearance in the first trimester. Am. J. Obstet. Gynecol. 1986;155:14 Kelly MD, Molo MW, Maclin VM,Binor Z, Rawlins RG,Rodwanska E. Human Chorionic Gonadotropin rise in normal and vanishing twin pregnancies. Fertil Steril 1991;56:221-4 Poikkeus P, Hiilesmaa V, Tiitinen A. Serum HCG 12 days after embryo transfer in predicting pregnancy outcome. Hum Reprod. 2002l;17:1901- 5 Mol BW, van der Veen F, Hajenius PJ, Engelsbel S, Ankum WM, Hogerzeil HV, Hemrika DJ, Bossuyt PM. Diagnosis of ectopic pregnancy after in vitro fertilization and embryo transfer. Fertil Steril
  • 1997;68:1027-32 Fritz MA, Gua S. Doubling time of human chorionic gonadotropin (hCG) in early normal pregnancy:relationship to hCG concentration and gestational age. Fertil Steril 1987;47:584-9 Pittaway DE, Reish RL, Wentz AC. Doubling times of human chorionic gonadotropin increase in early viable intrauterine pregnancies. Am J
  • Obstet Gynecol 1985;152:299-302 Daya S. Human chorionic gonadotropin increase in normal early pregnancy. Am J. Obstet Gynecol 1987;156:286-90 Urbancsek J, Hauzman E, Fedorcsak P, Halmos A, Devenyi N, Papp ZSerum human chorionic gonadotropin measurements may predict pregnancy outcome and multiple gestation after in vitro fertilization. Fertil Steril. 2002;78:540-2 Glatstein IZ, Hornstein MD, Kohana MJ, Jackson KV, Friedman AJ. The predictive value of discriminatory human chorionic gonadotropin levels in the diagnosis of implantation outcome in in vitro fertilization. Fertil Steril 1995;63:350- 56 Fridstorm M, Garaff L, Sjohlam P, Hillenjo T
  • Human chorionic gonadotropin patterns in early pregnancy after assisted reproduction. Acta Obstet Scand 1995;74:534-8 Schmidt LL, Asch RH, Frederick JL,Rojas FJ,Stone SC, Balmaceda JP. The predictive value of a single beta human chorionic gonadotropin in pregnancies achieved by assisted reproductive technology. Fertil Steril 1994;62:333-8 Dodson WC, Tyrey L,Haney AF. Serum human chorionic gonadotropin concentration for predicting multiple gestation in pregnancies conceived with superovulation and intrauterine insemination. J Reprod Med 1991;36:651-4 Keith SC,London SN, Weitzman GA, O'Brien TJ, Miller MM. Serial transvaginal ultrasound scans and b human chorionic gonadotropin levels in early singleton and multiple pregnancies. Fertil Steril.1993;59:1007-10 Liu HC, Kreiner B, Muasher SJ, Jones G, Jones Jr H, Rosenvaks Z. B human chorionic gonadotropin as a monitor of pregnancy outcome in in vitro fertilization-embryo transfer patients
  • Fertil Steril. 1998;50:89-94

Details

Primary Language Turkish
Journal Section Articles
Authors

Ulun ULUĞ This is me


Esra Aksoy JOZWIAK This is me


Süleyman TOSUN This is me


Mustafa BAHÇECİ This is me

Publication Date March 1, 2006
Published in Issue Year 2006, Volume 37, Issue 2

Cite

Bibtex @ { zktipb236856, journal = {Zeynep Kamil Tıp Bülteni}, issn = {1300-7971}, eissn = {2148-4864}, address = {}, publisher = {Zeynep Kamil Kadın ve Çocuk Hastalıkları EAH}, year = {2006}, volume = {37}, number = {2}, pages = {29 - 32}, doi = {10.16948/zktb.25552}, title = {The rate of increase in serum Beta hCG levels during the first 8 weeks of gestational life is not constatnt and different between singletons and twins}, key = {cite}, author = {Uluğ, Ulun and Jozwıak, Esra Aksoy and Tosun, Süleyman and Bahçeci, Mustafa} }
APA Uluğ, U. , Jozwıak, E. A. , Tosun, S. & Bahçeci, M. (2006). The rate of increase in serum Beta hCG levels during the first 8 weeks of gestational life is not constatnt and different between singletons and twins . Zeynep Kamil Tıp Bülteni , 37 (2) , 29-32 . Retrieved from https://dergipark.org.tr/en/pub/zktipb/issue/22059/236856
MLA Uluğ, U. , Jozwıak, E. A. , Tosun, S. , Bahçeci, M. "The rate of increase in serum Beta hCG levels during the first 8 weeks of gestational life is not constatnt and different between singletons and twins" . Zeynep Kamil Tıp Bülteni 37 (2006 ): 29-32 <https://dergipark.org.tr/en/pub/zktipb/issue/22059/236856>
Chicago Uluğ, U. , Jozwıak, E. A. , Tosun, S. , Bahçeci, M. "The rate of increase in serum Beta hCG levels during the first 8 weeks of gestational life is not constatnt and different between singletons and twins". Zeynep Kamil Tıp Bülteni 37 (2006 ): 29-32
RIS TY - JOUR T1 - Serum Beta hCG artış hızı gebeliğin ilk 8 haftasında sabit değil ve ikiz gebeler ile tekiz gebeliklerde farklıdır AU - UlunUluğ, Esra AksoyJozwıak, SüleymanTosun, MustafaBahçeci Y1 - 2006 PY - 2006 N1 - DO - T2 - Zeynep Kamil Tıp Bülteni JF - Journal JO - JOR SP - 29 EP - 32 VL - 37 IS - 2 SN - 1300-7971-2148-4864 M3 - UR - Y2 - 2022 ER -
EndNote %0 Medical Bulletin of Zeynep Kamil The rate of increase in serum Beta hCG levels during the first 8 weeks of gestational life is not constatnt and different between singletons and twins %A Ulun Uluğ , Esra Aksoy Jozwıak , Süleyman Tosun , Mustafa Bahçeci %T The rate of increase in serum Beta hCG levels during the first 8 weeks of gestational life is not constatnt and different between singletons and twins %D 2006 %J Zeynep Kamil Tıp Bülteni %P 1300-7971-2148-4864 %V 37 %N 2 %R %U
ISNAD Uluğ, Ulun , Jozwıak, Esra Aksoy , Tosun, Süleyman , Bahçeci, Mustafa . "The rate of increase in serum Beta hCG levels during the first 8 weeks of gestational life is not constatnt and different between singletons and twins". Zeynep Kamil Tıp Bülteni 37 / 2 (March 2006): 29-32 .
AMA Uluğ U. , Jozwıak E. A. , Tosun S. , Bahçeci M. The rate of increase in serum Beta hCG levels during the first 8 weeks of gestational life is not constatnt and different between singletons and twins. Zeynep Kamil Tıp Bülteni. 2006; 37(2): 29-32.
Vancouver Uluğ U. , Jozwıak E. A. , Tosun S. , Bahçeci M. The rate of increase in serum Beta hCG levels during the first 8 weeks of gestational life is not constatnt and different between singletons and twins. Zeynep Kamil Tıp Bülteni. 2006; 37(2): 29-32.
IEEE U. Uluğ , E. A. Jozwıak , S. Tosun and M. Bahçeci , "The rate of increase in serum Beta hCG levels during the first 8 weeks of gestational life is not constatnt and different between singletons and twins", Zeynep Kamil Tıp Bülteni, vol. 37, no. 2, pp. 29-32, Mar. 2006, doi:10.16948/zktb.25552