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The evaluation of the tubal patency after ectopic pregnancy treatment (laparoscopic salpingostomy and systemic methotrexate)

Year 2007, Volume: 38 Issue: 3, 93 - 97, 01.04.2007

Abstract

Aim: To evaluate tubal patency in patients with ectopic pregnancy treated by laparoscopic salpingostomy and systemic single dose methotreaxate Materials and Methods: This study was included 28 patients with ectopic pregnancy treated by laparoscopic salpingostomy and 14 patients with ectopic pregnancy treated by 50 mg/m2 single dose methotrexate, from January 2005 to July 2007. All patients were evaluated by hysterosalpingography after after three months contraception. SPSS for Windows 13.0 was used for statistical analysis. Results: The mean age was 30.6±4.5 in patients treated-by laparoscopy, whereas it was 30.07±3.6 in patients treated by methotrexate (p: 0,68). Gravidity andpartity were 0,92±l,ll and 0,50 ± 0,63 in patients treated by laparoscopy, whereas they were 0,78 ±0,8 and 0,5 ±0,65 in patients treated by methotrexate respectively. There were 8 patients (28,6 %) with ipsilateral tubal oclusion in laparoscopy group, whereas there were 5 patients (%37.5) with ipsilateral tubal oclusion in methotrexate group. Conclusion: Our results showed that the ipsilateral and contralateral tubal oclusion rate is similar in both groups. Tubal oclusion rate appears similar in patients with ectopic pregnancy treated with appropriate criteria.

References

  • 1. Stabile, L, Grudzinskas, J.G., Ectopic pregnancy: What's new I Prog., Obstet Gyneacol, 11, 281- 310, 1994
  • 2. Breen, J.L., A 21 year survey of 654 ectopic pregnancies, Am J Obstet Gynecol, 106, 1004, 1970
  • 3. Grainger, D.A., Seifer, D.3., Laparoscopic management of ectopic pregnancy, Current Opinion Obstet Gynecol., 7, 277- 282, 1995
  • 4. Buster, J.E., Carson, S.A., Ectopic pregnancy: new advances in diagnosis and treatment, Current Opinion Obstet Gynecol Scand., 73, 746 -752, 1994
  • 5. Stovall, T.G., Ling, F.W., Buster, J.E., Outpatient chemotherapy of unraptured ectopic pregnancy, Fertil Steril, 51, 435- 438, 1989
  • 6. Guvendag Güven, E.S., Dilbaz, S., Dilbaz, B., Ozdemir, D. S., Akdag, D., Haberal, A., Comparison of the effect of single-dose and multiple-dose methotrexate therapy on tubal patency,Fertil Steril
  • 2007 Apr 6; [Epub ahead of print] 7. Lundorff, P., Thorburn, J., Hahlin, M., Kallfelt, B., Lindblom, B., Laparoscopic surgery in ectopic pregnancy. A randomized trial versus laparotomy, Acta Obstetricia et Gynecologica Scandinavica, 70,343-348, 1991
  • 8. Vermesh, M., Suva, P.D., Rosen, G.F., Stein, A.L., Fossum, G.T., Sauer, M.V., Management of unruptured ectopic gestation by linear salpingostomy: a prospective, randomized clinical trial of laparoscopy versus laparotomy, Obstetrics & Gynecology, 73, 400-404, 1989
  • 9. Sowter, M.C., Farquhar, CM., Petrie, K.J., Gudex, G., A randomised trial comparing single dose systemic methotrexate and laparoscopic surgery for the' treatment of unruptured tubal pregnancy,, 108(2), 192-203, 2001
  • 10. Hajenius, PJ., Engelsbel, S., Mol, BW., Van der Veen, F., Ankum, WM., Bossuyt, PM., Hemrika, DJ., Lammes, FB., Randomised trial of systemic methotrexate versus laparoscopic salpingostomy in tubal pregnancy, Lancet, 13 350 (9080), 774- 779, 1997
  • 11. Saraj, A.J., Wilcox, J.G., Najmabadi, S., Stein, S.M., Johnson, M.B., Paulson, R.J. Resolution of hormonal markers of ectopic gestation: a randomized trial comparing single dose intramuscular methotrexate with salpingostomy, Obstetrics & Gynecology, 92, 989-994, 1998
  • 12. El-Sherbiny, M.T., El-Gharieb, I.H., Mera, I.M., Methotrexate verus laparoscopic surgery for the management of unruptured tubal pregnancy, Middle east Fertility Society Journal, 8(3), 256-262, 2003
  • 13. Colacurci, N., Zarcona, N., de Franciscis, P., Mele, Mollo, A., de Placido, G., Tubal patency after laparoscopic treatment of ectopic pregnancy
  • Panminevra Med., 40(1), 45-47, 1998
  • 14. Elito, J., Han, K.K., Camano, L., Values of beta-human chorionic gonadotropin as a risk factor for tubal obstruction after tubal pregnancy, Acta Obstet Gynecol Scand. , 84(9), 864-867, 2005
  • 15. Elito, J., Han, K.K., Camano, L.,Tubal patency after clinical treatment of unruptured ectopic pregnancy, Int J Gynecol Obstet., 88(3), 309-313, 2005.

Ektopik gebelik tedavisi sonrasında (laparoskopik salpingostomi ve sistemik methotrexate) tubal patensin değerlendirilmesi

Year 2007, Volume: 38 Issue: 3, 93 - 97, 01.04.2007

Abstract

Amaç: Laparoskopik salpingostomi ve sistemik tek doz Methotrexate uygulanan hastalarda tubal tedavi sonrası tubal patensi değerlendirmektir. Gereç ve Yöntem: Bu çalışma Ocak 2005-Temmuz 2007 tarihleri arasında, Ektopik gebelik tanısı ile laparoskopik salpingostomi uygulanan 28 hasta ve 50 mg/m2 tek doz Methotrexate uygulanan 14 hasta da yapılmıştır. Hastaların tümüne 3 aylık kontrasepsiyon sonrası tubal patensinin değerlendirilmesi amacı ile histerosalpingografı planlandı. İstatistiksel analiz için, SPSS for Windows 13.0 paket programı kullanıldı. Bulgular: Laparoskopik salpingostomi uygulanan grupta ortalama yaş 30,6 (-/+ 4,5) iken, Methotrexate uygulanan grupta ise 30,07 (-/+ 3,6) idi.(p: 0,68) Hastaların gravida ve par iteler i değerlendirildiğinde sırası ile laparoskopik salpingostomi uygulanan grupta 0,92 (-/+ 1,11), 0,50 (-/+ 0,63) iken; Methotrexate uygulanan grupta ise 0,78 (-/+ 0,8), 0,5 (-/+ 0,65) idi. Laparoskopik salpingostomi uygulanan hastaların 8 inde (% 28,6) ipsilateral tubal obstrüksiyon izlenirken, tek doz 50 mg/m2 Methotrexate tedavisi uygulanan hastalardan 5 inde (% 35,7) ipsilateral obstrüksiyon izlendi. Sonuç: Elde edilen veriler ipsilateral tubal obstrüksiyon oranı ve kontralateral tubal obstrüksiyon oranı her iki grupta benzer olarak bulunmuştur. Tubal geçirgenlik üzerinde; unrüptüre ektopik gebelik olgularında uygun kriterlere göre davranıldığı zaman anlamlı fark göstermemektedir.

References

  • 1. Stabile, L, Grudzinskas, J.G., Ectopic pregnancy: What's new I Prog., Obstet Gyneacol, 11, 281- 310, 1994
  • 2. Breen, J.L., A 21 year survey of 654 ectopic pregnancies, Am J Obstet Gynecol, 106, 1004, 1970
  • 3. Grainger, D.A., Seifer, D.3., Laparoscopic management of ectopic pregnancy, Current Opinion Obstet Gynecol., 7, 277- 282, 1995
  • 4. Buster, J.E., Carson, S.A., Ectopic pregnancy: new advances in diagnosis and treatment, Current Opinion Obstet Gynecol Scand., 73, 746 -752, 1994
  • 5. Stovall, T.G., Ling, F.W., Buster, J.E., Outpatient chemotherapy of unraptured ectopic pregnancy, Fertil Steril, 51, 435- 438, 1989
  • 6. Guvendag Güven, E.S., Dilbaz, S., Dilbaz, B., Ozdemir, D. S., Akdag, D., Haberal, A., Comparison of the effect of single-dose and multiple-dose methotrexate therapy on tubal patency,Fertil Steril
  • 2007 Apr 6; [Epub ahead of print] 7. Lundorff, P., Thorburn, J., Hahlin, M., Kallfelt, B., Lindblom, B., Laparoscopic surgery in ectopic pregnancy. A randomized trial versus laparotomy, Acta Obstetricia et Gynecologica Scandinavica, 70,343-348, 1991
  • 8. Vermesh, M., Suva, P.D., Rosen, G.F., Stein, A.L., Fossum, G.T., Sauer, M.V., Management of unruptured ectopic gestation by linear salpingostomy: a prospective, randomized clinical trial of laparoscopy versus laparotomy, Obstetrics & Gynecology, 73, 400-404, 1989
  • 9. Sowter, M.C., Farquhar, CM., Petrie, K.J., Gudex, G., A randomised trial comparing single dose systemic methotrexate and laparoscopic surgery for the' treatment of unruptured tubal pregnancy,, 108(2), 192-203, 2001
  • 10. Hajenius, PJ., Engelsbel, S., Mol, BW., Van der Veen, F., Ankum, WM., Bossuyt, PM., Hemrika, DJ., Lammes, FB., Randomised trial of systemic methotrexate versus laparoscopic salpingostomy in tubal pregnancy, Lancet, 13 350 (9080), 774- 779, 1997
  • 11. Saraj, A.J., Wilcox, J.G., Najmabadi, S., Stein, S.M., Johnson, M.B., Paulson, R.J. Resolution of hormonal markers of ectopic gestation: a randomized trial comparing single dose intramuscular methotrexate with salpingostomy, Obstetrics & Gynecology, 92, 989-994, 1998
  • 12. El-Sherbiny, M.T., El-Gharieb, I.H., Mera, I.M., Methotrexate verus laparoscopic surgery for the management of unruptured tubal pregnancy, Middle east Fertility Society Journal, 8(3), 256-262, 2003
  • 13. Colacurci, N., Zarcona, N., de Franciscis, P., Mele, Mollo, A., de Placido, G., Tubal patency after laparoscopic treatment of ectopic pregnancy
  • Panminevra Med., 40(1), 45-47, 1998
  • 14. Elito, J., Han, K.K., Camano, L., Values of beta-human chorionic gonadotropin as a risk factor for tubal obstruction after tubal pregnancy, Acta Obstet Gynecol Scand. , 84(9), 864-867, 2005
  • 15. Elito, J., Han, K.K., Camano, L.,Tubal patency after clinical treatment of unruptured ectopic pregnancy, Int J Gynecol Obstet., 88(3), 309-313, 2005.
There are 16 citations in total.

Details

Primary Language Turkish
Journal Section Articles
Authors

Namık Kemal Duru This is me

İbrahim Alanbay This is me

Murat Muhcu This is me

Uğur Keskin This is me

Vedat Atay This is me

Publication Date April 1, 2007
Published in Issue Year 2007 Volume: 38 Issue: 3

Cite

APA Duru, N. K., Alanbay, İ., Muhcu, M., Keskin, U., et al. (2007). Ektopik gebelik tedavisi sonrasında (laparoskopik salpingostomi ve sistemik methotrexate) tubal patensin değerlendirilmesi. Zeynep Kamil Tıp Bülteni, 38(3), 93-97. https://doi.org/10.16948/zktb.14100
AMA Duru NK, Alanbay İ, Muhcu M, Keskin U, Atay V. Ektopik gebelik tedavisi sonrasında (laparoskopik salpingostomi ve sistemik methotrexate) tubal patensin değerlendirilmesi. Zeynep Kamil Tıp Bülteni. April 2007;38(3):93-97. doi:10.16948/zktb.14100
Chicago Duru, Namık Kemal, İbrahim Alanbay, Murat Muhcu, Uğur Keskin, and Vedat Atay. “Ektopik Gebelik Tedavisi sonrasında (laparoskopik Salpingostomi Ve Sistemik Methotrexate) Tubal Patensin değerlendirilmesi”. Zeynep Kamil Tıp Bülteni 38, no. 3 (April 2007): 93-97. https://doi.org/10.16948/zktb.14100.
EndNote Duru NK, Alanbay İ, Muhcu M, Keskin U, Atay V (April 1, 2007) Ektopik gebelik tedavisi sonrasında (laparoskopik salpingostomi ve sistemik methotrexate) tubal patensin değerlendirilmesi. Zeynep Kamil Tıp Bülteni 38 3 93–97.
IEEE N. K. Duru, İ. Alanbay, M. Muhcu, U. Keskin, and V. Atay, “Ektopik gebelik tedavisi sonrasında (laparoskopik salpingostomi ve sistemik methotrexate) tubal patensin değerlendirilmesi”, Zeynep Kamil Tıp Bülteni, vol. 38, no. 3, pp. 93–97, 2007, doi: 10.16948/zktb.14100.
ISNAD Duru, Namık Kemal et al. “Ektopik Gebelik Tedavisi sonrasında (laparoskopik Salpingostomi Ve Sistemik Methotrexate) Tubal Patensin değerlendirilmesi”. Zeynep Kamil Tıp Bülteni 38/3 (April 2007), 93-97. https://doi.org/10.16948/zktb.14100.
JAMA Duru NK, Alanbay İ, Muhcu M, Keskin U, Atay V. Ektopik gebelik tedavisi sonrasında (laparoskopik salpingostomi ve sistemik methotrexate) tubal patensin değerlendirilmesi. Zeynep Kamil Tıp Bülteni. 2007;38:93–97.
MLA Duru, Namık Kemal et al. “Ektopik Gebelik Tedavisi sonrasında (laparoskopik Salpingostomi Ve Sistemik Methotrexate) Tubal Patensin değerlendirilmesi”. Zeynep Kamil Tıp Bülteni, vol. 38, no. 3, 2007, pp. 93-97, doi:10.16948/zktb.14100.
Vancouver Duru NK, Alanbay İ, Muhcu M, Keskin U, Atay V. Ektopik gebelik tedavisi sonrasında (laparoskopik salpingostomi ve sistemik methotrexate) tubal patensin değerlendirilmesi. Zeynep Kamil Tıp Bülteni. 2007;38(3):93-7.