Comparison of uterin artery doppler indices, endometrial thickness and histopathological findings of symptomatic and asymptomatic postmenopausal women

Year 2008, Volume: 39 Issue: 4, 167 - 173, 01.05.2008

Barış Mülayim Zeki Şahinoğlu Sema Mülayim Habibe Ayvacı Umur Kuyumcuoğlu

Abstract

Objective: In this study we aimed to demonstrate the utility of Doppler Ultrasound (USG) as a screening tool by means of defining the sensitivity and specificity of Doppler USG findings and endometrial thickness in determining endometrial pathologies in postmenopausal women. Plan: Prospective Cohort Patients: 57 women with postmenopausal bleeding and 57 control women without postmenopausal bleeding. None of them received hormon replacement therapy. Tests: Doppler USG, Endometrial sampling Evaluation: Endometrial thickness and uterine artery Doppler indices were defined prior to endometrial sampling. Histopathological findings were compared with endometrial thickness and uterine artery RI and PI values. A p value of less than 0.05 was considered significant with a confidence interval of 95 %. Results: Sensitivity and specificity of endometrial thickness in (acceptedcut-off5.5 mm) determining endometrial pathologies were found to be % 76 and % 52. Sensitivity and specificity of uterine artery Doppler indices in determining endometrial pathologies were calculated alternately; right RI: 100%- 30%, leftRI: 83%- 52%, right PI: 100%-22%, left PI: 83%- 26%. Comment: Sensitivity and specificity of uterine artery Doppler indices in determining endometrial pathologies is significantly higher than sensitivity and specificity of endometrial thickness.

Keywords

Postmenopause, Histopathology, Endometrium, Sensitivity and Specificity, Ultrasonography, Doppler

Postmenopozal semptomatik ve asemtomatik olgularda uterin arter doppler indeks, endometrial kalınlık ve histopatolojik bulguların karşılaştırılması

Abstract

Objektif: Bu çalışmamızda, PMK'lı olgularda Doppler USG bulguları ve endometrium kalınlığının, endometrial patolojileri saptamadaki sensitivite ve spesifisitesini belirleyerek, Doppler USG nin bir tarama yöntemi olarak kullanılabilirliğini göstermeyi amaçladık. Planlama : Pro sp ektif Kohort Hastalar: Hormon replasman tedavisi almayan postmenopozal kanaması olan 57 olgu ve kontrol grubunu oluşturan postmenopozal kanaması olmayan 57 olgu. Girişim: Doppler Ultrasonografı, Endometrial Örnekleme. Değerlendirme: Endometrial örnekleme öncesi, endometrium kalınlıkları ve uterin arter doppler indeksleri belirlendi. Histo-patolojik bulgular ile endometrium kalınlığı ve uterin arter RI ve PI değerleri karşılaştırıldı. Sonuçlar %95'likgüven aralığında,p

Keywords

Postmenopoz, Histopatoloji, Endometriyum, Duyarlılık ve özgüllük, Ultrasonografi, doppler

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