Comparison of the sperm anlysis after six months intervals on the same patients

Year 2008, Volume: 39 Issue: 4, 181 - 185, 01.05.2008

Ranan Gülhan Aktaş Naciye Arat Handan Ankaralı Kenan Sofuoğlu Tansel Çetinkaya Belgin Devranoğlu Arman Özdemir Selçuk Ayas

Abstract

Introduction: The aim of the study were (i) statistical analysis of two different semen analysis results on the same patients after six months intervals and (ii) to examine if there are seasonal variations on semen parameterst. Material and Methods: Semen parameters of 56 patients who applied to the Andrology Laboratory of Assisted Reproductive Center of Zeynep Kamil Women and Children Diseases' Hospital were analysed by using Kolmogorov-Smirnov test and paired t-test. Results: There were increase on sperm count and motility on the same patients who gave samples two times with six months intervals (on March-April-May and September-October or November). However; this increase was not statistical meaningful. Conclusions: Statistical meaningful differences on the parameters of semen analysis of same patients were not observed. The results were pretty consistents; in spite of it is well known that the results could be effected by many factors. We also conclude that semen analysis is still very valuable since it is one of the most trustable, easiest and the cheapest method.

Keywords

Sperm Count, Sperm Motility, Seasons, Semen Analysis

Aynı hastalarda altı aylık aralarla tekrarlanan sperm analizlerinin karşılaştırmalı değerlendirilmesi

Abstract

Amaç: Aynı hastada 6 aylık aralıklarla semen analizi tekrarlandığında, sonuçların değişkenlik gösterip göstermediği ve mevsimsel farklılıkların ortaya çıkıp çıkmadığının istatistiksel olarak incelenmesi amaçlanmıştır. Materyal ve Metod: Zeynep Kamil Kadın ve Çocuk Hastalıkları Hastanesi Üremeye Yardımcı Tedaviler Merkesi Androloji lab or atuv arına altı aylık aralıklarla başvuran 56 hastanın iki semen analizi karşılıklı değerlendirilmiştir. İstatistiksel incelemeler; Kolmogorov-Smirnov testi and paired t-testi kullanılarak yapılmıştır. Bulgular: Mart-Nisan-Mayıs aylarında alınan örnekler; aynı hastaların Eylül-Ekim ya da Kasım aylarında alınan örneklerinin sonuçları ile karşılaştırıldığında; sperm sayı ve motilitesinde artış gözlenmiş; ancak bu artış istatistiksel olarak anlamlı bulunmamıştır. Tartışma: Aynı kişide altı aylık aralıklarla yapılan semen analizi sonuçları istatistiksel olarak anlamlı olacak derecede bir değişiklik göstermemektedir. Analiz sonuçlarının birbirine çok yakın olması; sperm parametrelerinin çok değişken olabileceğinin bilinmesine karşılık halen an güvenilir yöntemlerden birinin olduğunu da bir kez daha göstermektedir.

Keywords

Sperm sayısı, Sperm hareketliliği, Mevsimler, Semen analizi

References

• 1-Kalyani R, Basavaraj PB, Kumar ML. Factors influencing quality of semen: a two year prospective study.Indian J Pathol Microbiol. 2007 Oct;50(4):890-5
• 2-Goverde HJ, Dekker HS, Janssen HJ, Bastiaans BA, Rolland R, Zielhuis GA. Semen quality and frequency of smoking and alcohol consumption— an explorative study. Int J Fertil Menopausal Stud. 1995 May-Jun;40(3): 135-8
• 3-Deepener F, Makker K, AgarwalA. Cellphones and male infertility: dissecting the relationship.Reprod Biomed Online. 2007 Sep;15(3):266-70
• 4-Derias EM, Stefanis P, Drakeley A, Gazvani R, Lewis-Jones DI. Growing concern over the safety of using mobile phones and male fertility. Arch Androl. 2006 Jan-Feb;52(l):9-14
• 5-Auger J, Jouannet P. Age and male fertility: biological factors. Rev Epidemiol Sante Publique. 2005 Nov;53 Spec No 2:2S25-35
• 6-Joffe M. Decreased fertility in Britain compared with Finland.Lancet. 1996 Jun l;347(9014):1519-22
• 7-Jensen TK, Vierula M, Hjollund NH, Saaranen M, Scheike T, Saarikoski S, Suominen J, Keiski A, Toppari J, Skakkebaek NE. Semen quality among Danish and Finnish men attempting to conceive. The Danish First Pregnancy Planner Study Team
• 8- Sripada S, Fonseca S, Lee A, Harrild K, Giannaris D, Mathers E, Bhattacharya S. Trends in semen parameters in the northeast of Scotland. Eur J Endocrinol. 2000 Jan;142(l):47-52
• 9-ZornB, Virant-KlunI, VerdenikI, Meden-Vrtovec H. Semen quality changes among 2343 healthy Slovenian men included in an IVF-ETprogramme from 1983 to 1996. Int J Androl. 1999 Jun;22(3):178-83
• 10-Benshushan A, Shoshani O, Paltiel O, Schenker JG, Lewin A. Is there really a decrease in sperm parameters among healthy young men? A survey of sperm donations during 15 years. J Assist Reprod Genet. 1997Jul; 14(6): 347-53
• 11-Paulsen CA, Berman NG, Wang C. Data from men in greater Seattle area reveals no downward trend in semen quality: further evidence that deterioration of semen quality is not geographically uniform. Fertil Steril. 1996 May;65(5): 1015-20
• 12- Carls en E, Giwercman A, Keiding N, Skakkebaek NE. Evidence for decreasing quality of semen during past 50 years. BMJ. 1992 Sep 12;305(6854):609-13., 13-Carlsen E, Giwercman AJ, Keiding N, Skakkebaek NE. Decline in semen quality from 1930 to 1991. Ugeskr Laeger. 1993 Aug 16;155(33):2530-5
• 14-Osser S, Liedholm P, Ranstam J. Depressed semen quality: a study over two decades. Arch Androl. 1984;12(l):113-6
• 15-BendvoldE. Semen quality in Norwegian men over a 20-year period. Int J Fertil. 1989 Nov-Dec;34(6):401-4
• 16-BendvoldE, Gottlieb C, Bygdeman M, Eneroth P. Depressed semen quality in Swedish men from barren couples: a study over three decades. Arch Androl. 1991 May-Jun;26(3): 189-94
• 17-Tjoa WS, Smolensky MH, Hsi BP, Steinberger E, Smith KD. Circannual rhythm in human sperm count revealed by serially independent sampling. Fertil Steril. 1982 Oct;38(4):454-9
• 18-Paraskevaides EC, Pennington GW, Naik S. Seasonal distribution in conceptions achieved by artificial insemination by donor BMJ. 1988 Nov 19;297(6659):1309-10
• 19-PolitoffL, Birkhauser M, Almendral A, Zorn A. New data confirming a circannual rhythm in spermatogenesis. Fertil Steril. 1989; 52(3):486-9
• 20-Levine RJ, Brown MH, Bell M, Shue F, Greenberg GN, Bordson BL. Air-conditioned environments do not prevent deterioration of human semen quality during the summer. Fertil Steril. 1992;57(5):1075-83
• 21-Centola GM, Eberly S. Seasonal variations and age-related changes in human sperm count, motility, motion parameters, morphology, and white blood cell concentration. Fertil Steril. 1999 Nov; 72(5): 803- 22-HenkelR, Menkveld R, Kleinhappl M, Schill WB. Seasonal changes in human sperm chromatin condensation. J Assist Reprod Genet. 2001 Jul;18(7):371-7 23-Krause A, Krause W. Seasonal variations in human seminal parameters. EurJ Obstet Gynecol ReprodBiol. 2002; 101 (2): 175-8
• 24-Chen Z, Godfrey-Bailey L, SchiffI, Hauser R. Impact of seasonal variation, age and smoking status on human semen parameters: The Massachusetts General Hospital experience JExp Clin Assist Reprod. 2004 Sep 30; 1(1):2 25-Sobreiro BP, LuconM, Pasqualotto FF, Hallak J, Athayde KS, Arap S. Semen analysis infertile patients undergoing vasectomy: reference values and variations according to age, length of sexual abstinence, seasonally, smoking habits and caffeine intake. Sao Paulo Med. J.2005 123 (4) 26-Minter LJ, DeLiberto TJ. Seasonal variation in serum testosterone, testicular volume, and semen characteristics in the coyote (Canis latrans. Theriogenology. 2008 May;69(8):946-52