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Histologic chorioamnionitis and preterm delivery

Year 2010, Volume 41, Issue 2, 59 - 63, 01.03.2010

Abstract

Objective: To determine the effects of histological chorioamnionitis in preterm delivery and to investigate the other causes. Material and Methods: The study group consisted of 65 preterm and 71 term pregnancies who are singleton, in active labor and without rupture of membranes. The patients were questioned about their obstetric history, and blood, urine sample for laboratory analysis and vaginal culture were obtained. All placentas were evaluated histopathologically and searched for histological chorioamnionitis. Results: In 2 (3.1%) of 65 preterm labors and 1 (%1.4) of 71 term labors, histological chorioamnionitis was detected. In terms of histological chorioamnionitis, there was no statistical difference between the groups (p>0.05). Also, in terms of history of previous cesarean section, gestational diabetes mellitus and history of urinary tract infection, statistically significant difference were present between preterm and term groups (p=0.007, 0.043, 0.04). Conclusion: The result of our study does not show the relationship between histological chorioamnionitis and preterm delivery. It might be due to the small size of our sample group. Therefore, a better understanding of the presence of histological chorioamnionitis on preterm delivery, there is requirement of longdated several studies.

References

  • 1. Lettieri L, Vintzileos AM, Rodis JF, Albini SM, Salafia CM. Does idiopathic preterm labor resulting in preterm birth exist? AmJObstet Gynecol 1993; 168:1480-5
  • 2. Hack M, Fanaroff A A. Outcomes of extremely immature infants-a perinatal dilemma. N Engl J Med 1985; 312:82-90
  • 3.Rush RW, Keirse MJNC, Howat P, Baum JD, Andersen ABM, Turnbull AC. Contribution of preterm delivery to perinatal mortality.Br Med J 1976-2 : 965-8
  • 4. Gibbs RS, Romeo R, Hillier SL, Eschenbach DA, Sweet RL.A review of premature birth and subclinical infection.Am J Obstet Gynecol 1992;166:1515-28
  • 5. MinkojfH. Prematurity: infection as an etiologic factor. Obstet Gynecol 1983;62: 137-44
  • 6. Hillier SL, Martius J, Krohn MA, Kiviat NB, Holmes KK, Eschenbach DA.A case-control study of chorioamnionic infection and histologic chorioamnionitis in prematurity. N Engl J Med 1988; 319:972-8
  • 7. Aquino TI, Zhang J, Kraus FT, Knefel R, Taff T. Subchorionic fibrin cultures for bacteriologic study of the placenta. Am J Clin Pathol 1984; 81:482-6
  • 8. Svensson L, Ingermarsson I, Mardh PA.Chorioamnionitis and the isolation of microorganisms from the placenta. Obstet Gynecol 1986; 67: 403-9
  • 9. Larson JF, Eldon K, Lange AP, et al. Ritodrine in the treatment of preterm labor: second Danish multicenter study.Obstet Gynecol 1986; 67: 607-13
  • 10. Ballard J, Novak KK, Driver M.A simplified score for assessment of fetal maturation of newly born infants.J Pediatr 1979; 95: 769-74
  • 11. Salafia CM, Weigl C, SilbermanL.Theprevalence and distribution of acute placental inflammation in uncomplicated term pregnancies. Obstet Gynecol 1989; 73:383-98
  • 12. Romero R, Sirtori M, Oyarzun E, et al.Infection and labor. V. Prevalance, microbiology, and clinical significance of intraamniotic infection in women with preterm labor and intact membranes. Am J Obstet Gynecol 1989; 161:817-24
  • 13.Romero R, Espinoza J, Goncalves LF, Kusanovic JP, Friel L, Hassan S.The role of inflamation and infection in preterm birth. Semin Reprod Med2007; 25:21-39
  • 14. Romero R, Espinoza J, Goncalves LF, Kusanovic JP, Friel LA, Nien JK.Inflammtion in preterm and term labour and delivery. Seminars in Fetal and Neonatal Medicine 2006; 11: 317-26
  • 15. DujfP, Kopelman JN.Subclinical intra-amniotic infection in asymptomatic patients with refractory preterm labor. Obstet Gynecol 1987; 69: 756-9
  • 16. Guzick DS, Winn K.The association of chorioamnionitis with preterm delivery. Obstet Gynecol 1985; 65:11-6
  • 17. Hillier SL, Krohn MA, Kiviat NB, Watts DH, Eschenbach DA. Microbiologic causes and neonatal outcomes associated with choriamnion infection.Am J Obstet Gynecol. 1991; 165:955-61
  • 18. Mays JK, Figueroa R, Shah J, Khakoo H, Kaminsky S, Tejani N. Amniocentesis for selection bfore rescue cerclage. Obstet Gynecol 2000; 95:652
  • 19. Romero R, Gonzalez R, Sepulveda W, Brandt F, Ramirez M, Sorokin Y, Mazor M, Treadwell MC, Cotton DB. Infection and labor. VIII. Microbial invasion of the amniotic cavity in patients with suspected cervical incompetence: prevalence and clinical significance. Am J Obstet Gynecol. 1992 ;167:1086-91
  • 20. Gray DJ, Robinson HB, Malone J, Thomson RB Jr. Adverse outcome in pregnancy following amniotic fluid isolation ofUreoplasma urealyticum
  • 21. Abu Hamad Kh, Abed Y, Abu Hamad B. Risk factors associated with preterm birth in the Gaza Strip: hospital-based case-control study. East Mediterr Health J 2007; 13:1132-41
  • 22. Covarrubias LO, Aguirre GE, Chapuz JR, May AI, Velazquez JD, Eguiluz ME Maternal factors associated to prematurity Ginecol Obstet Mex. 2008; 76:526-36
  • 23. McDonald HM, Brocklehurst P, Gordon A. Antibiotics for treating bacterial vaginosis in pregnancy. Cochrane Database Syst Rev. 2007; 24.CD000262
  • 24. SimcoxR, Sin WT, Seed PT, Briley A, Shennan AH. Prophylactic antibiotics for the prevention of preterm birth in women at risk: a meta-analysis. Aust N ZJ Obstet Gynaecol 2007; 47:368-77

Histolojik koioamnionitin erken doğum üzerindeki etkisi

Year 2010, Volume 41, Issue 2, 59 - 63, 01.03.2010

Abstract

Amaç: Histolojik korioamniorıitin erken doğum üzerindeki etkisini ve erken doğumu etkileyen diğer faktörleri araştırmak amaçlanmıştır.. Yöntem: Çalışmada aktif eylemde olan , erken membrane rupture olmayan ve tekil gebelikleri içeren 65 preterm ve 71 term gebelerden alınan plasentalar histopatolojik olarak incelenmiştir. Bunun yanında tüm hastalardan obstetric anamnez, kan, idrar ve vajinal kültür örnekleri alınarak olası etiyolojik faktörler araştırılmıştır. Bulgular: Plasentaların histopatolojik olarak incelenmesi sonrası preterm doğumlar içerisinde 2 (3.1%), term doğumlar içerisinde 1 (%1.4) oranında histolojik korioamnit saptanmıştır. Geçirilmiş sezaryen doğum öyküsü, bu gebeliğinde saptanan gestasyonel diyabet ve idrar yolu enfeksiyonu hikayesi pretem doğum yapan gebelerde istatiksel anlamlı olarak daha yüksek bulunmuştur. Sonuç: Bu çalışmanın sonucunda histolojik koryoamniyonit ve preterm doğum ilişkisi koryoamniyonit vakalarının sayıca yetersiz olmasından dolayı söylenemez.Bu nedenle bu konuda daha fazla sayıda ve uzun süreli çalışmalara ihtiyaç vardır.

References

  • 1. Lettieri L, Vintzileos AM, Rodis JF, Albini SM, Salafia CM. Does idiopathic preterm labor resulting in preterm birth exist? AmJObstet Gynecol 1993; 168:1480-5
  • 2. Hack M, Fanaroff A A. Outcomes of extremely immature infants-a perinatal dilemma. N Engl J Med 1985; 312:82-90
  • 3.Rush RW, Keirse MJNC, Howat P, Baum JD, Andersen ABM, Turnbull AC. Contribution of preterm delivery to perinatal mortality.Br Med J 1976-2 : 965-8
  • 4. Gibbs RS, Romeo R, Hillier SL, Eschenbach DA, Sweet RL.A review of premature birth and subclinical infection.Am J Obstet Gynecol 1992;166:1515-28
  • 5. MinkojfH. Prematurity: infection as an etiologic factor. Obstet Gynecol 1983;62: 137-44
  • 6. Hillier SL, Martius J, Krohn MA, Kiviat NB, Holmes KK, Eschenbach DA.A case-control study of chorioamnionic infection and histologic chorioamnionitis in prematurity. N Engl J Med 1988; 319:972-8
  • 7. Aquino TI, Zhang J, Kraus FT, Knefel R, Taff T. Subchorionic fibrin cultures for bacteriologic study of the placenta. Am J Clin Pathol 1984; 81:482-6
  • 8. Svensson L, Ingermarsson I, Mardh PA.Chorioamnionitis and the isolation of microorganisms from the placenta. Obstet Gynecol 1986; 67: 403-9
  • 9. Larson JF, Eldon K, Lange AP, et al. Ritodrine in the treatment of preterm labor: second Danish multicenter study.Obstet Gynecol 1986; 67: 607-13
  • 10. Ballard J, Novak KK, Driver M.A simplified score for assessment of fetal maturation of newly born infants.J Pediatr 1979; 95: 769-74
  • 11. Salafia CM, Weigl C, SilbermanL.Theprevalence and distribution of acute placental inflammation in uncomplicated term pregnancies. Obstet Gynecol 1989; 73:383-98
  • 12. Romero R, Sirtori M, Oyarzun E, et al.Infection and labor. V. Prevalance, microbiology, and clinical significance of intraamniotic infection in women with preterm labor and intact membranes. Am J Obstet Gynecol 1989; 161:817-24
  • 13.Romero R, Espinoza J, Goncalves LF, Kusanovic JP, Friel L, Hassan S.The role of inflamation and infection in preterm birth. Semin Reprod Med2007; 25:21-39
  • 14. Romero R, Espinoza J, Goncalves LF, Kusanovic JP, Friel LA, Nien JK.Inflammtion in preterm and term labour and delivery. Seminars in Fetal and Neonatal Medicine 2006; 11: 317-26
  • 15. DujfP, Kopelman JN.Subclinical intra-amniotic infection in asymptomatic patients with refractory preterm labor. Obstet Gynecol 1987; 69: 756-9
  • 16. Guzick DS, Winn K.The association of chorioamnionitis with preterm delivery. Obstet Gynecol 1985; 65:11-6
  • 17. Hillier SL, Krohn MA, Kiviat NB, Watts DH, Eschenbach DA. Microbiologic causes and neonatal outcomes associated with choriamnion infection.Am J Obstet Gynecol. 1991; 165:955-61
  • 18. Mays JK, Figueroa R, Shah J, Khakoo H, Kaminsky S, Tejani N. Amniocentesis for selection bfore rescue cerclage. Obstet Gynecol 2000; 95:652
  • 19. Romero R, Gonzalez R, Sepulveda W, Brandt F, Ramirez M, Sorokin Y, Mazor M, Treadwell MC, Cotton DB. Infection and labor. VIII. Microbial invasion of the amniotic cavity in patients with suspected cervical incompetence: prevalence and clinical significance. Am J Obstet Gynecol. 1992 ;167:1086-91
  • 20. Gray DJ, Robinson HB, Malone J, Thomson RB Jr. Adverse outcome in pregnancy following amniotic fluid isolation ofUreoplasma urealyticum
  • 21. Abu Hamad Kh, Abed Y, Abu Hamad B. Risk factors associated with preterm birth in the Gaza Strip: hospital-based case-control study. East Mediterr Health J 2007; 13:1132-41
  • 22. Covarrubias LO, Aguirre GE, Chapuz JR, May AI, Velazquez JD, Eguiluz ME Maternal factors associated to prematurity Ginecol Obstet Mex. 2008; 76:526-36
  • 23. McDonald HM, Brocklehurst P, Gordon A. Antibiotics for treating bacterial vaginosis in pregnancy. Cochrane Database Syst Rev. 2007; 24.CD000262
  • 24. SimcoxR, Sin WT, Seed PT, Briley A, Shennan AH. Prophylactic antibiotics for the prevention of preterm birth in women at risk: a meta-analysis. Aust N ZJ Obstet Gynaecol 2007; 47:368-77

Details

Primary Language Turkish
Journal Section Articles
Authors

Oya DEMİRCİ This is me


Özlem BOZOKLU This is me


Elif DEMİRCİ This is me


Semih TUĞRUL This is me


Ayşe GÜRBÜZ This is me


Sadiye EREN This is me


Handan ÇETİNER This is me

Publication Date March 1, 2010
Published in Issue Year 2010, Volume 41, Issue 2

Cite

Bibtex @ { zktipb237017, journal = {Zeynep Kamil Tıp Bülteni}, issn = {1300-7971}, eissn = {2148-4864}, address = {}, publisher = {Zeynep Kamil Kadın ve Çocuk Hastalıkları EAH}, year = {2010}, volume = {41}, number = {2}, pages = {59 - 63}, doi = {10.16948/zktb.54444}, title = {Histolojik koioamnionitin erken doğum üzerindeki etkisi}, key = {cite}, author = {Demirci, Oya and Bozoklu, Özlem and Demirci, Elif and Tuğrul, Semih and Gürbüz, Ayşe and Eren, Sadiye and Çetiner, Handan} }
APA Demirci, O. , Bozoklu, Ö. , Demirci, E. , Tuğrul, S. , Gürbüz, A. , Eren, S. & Çetiner, H. (2010). Histolojik koioamnionitin erken doğum üzerindeki etkisi . Zeynep Kamil Tıp Bülteni , 41 (2) , 59-63 . Retrieved from https://dergipark.org.tr/en/pub/zktipb/issue/22077/237017
MLA Demirci, O. , Bozoklu, Ö. , Demirci, E. , Tuğrul, S. , Gürbüz, A. , Eren, S. , Çetiner, H. "Histolojik koioamnionitin erken doğum üzerindeki etkisi" . Zeynep Kamil Tıp Bülteni 41 (2010 ): 59-63 <https://dergipark.org.tr/en/pub/zktipb/issue/22077/237017>
Chicago Demirci, O. , Bozoklu, Ö. , Demirci, E. , Tuğrul, S. , Gürbüz, A. , Eren, S. , Çetiner, H. "Histolojik koioamnionitin erken doğum üzerindeki etkisi". Zeynep Kamil Tıp Bülteni 41 (2010 ): 59-63
RIS TY - JOUR T1 - Histologic chorioamnionitis and preterm delivery AU - OyaDemirci, ÖzlemBozoklu, ElifDemirci, SemihTuğrul, AyşeGürbüz, SadiyeEren, HandanÇetiner Y1 - 2010 PY - 2010 N1 - DO - T2 - Zeynep Kamil Tıp Bülteni JF - Journal JO - JOR SP - 59 EP - 63 VL - 41 IS - 2 SN - 1300-7971-2148-4864 M3 - UR - Y2 - 2022 ER -
EndNote %0 Medical Bulletin of Zeynep Kamil Histolojik koioamnionitin erken doğum üzerindeki etkisi %A Oya Demirci , Özlem Bozoklu , Elif Demirci , Semih Tuğrul , Ayşe Gürbüz , Sadiye Eren , Handan Çetiner %T Histolojik koioamnionitin erken doğum üzerindeki etkisi %D 2010 %J Zeynep Kamil Tıp Bülteni %P 1300-7971-2148-4864 %V 41 %N 2 %R %U
ISNAD Demirci, Oya , Bozoklu, Özlem , Demirci, Elif , Tuğrul, Semih , Gürbüz, Ayşe , Eren, Sadiye , Çetiner, Handan . "Histolojik koioamnionitin erken doğum üzerindeki etkisi". Zeynep Kamil Tıp Bülteni 41 / 2 (March 2010): 59-63 .
AMA Demirci O. , Bozoklu Ö. , Demirci E. , Tuğrul S. , Gürbüz A. , Eren S. , Çetiner H. Histolojik koioamnionitin erken doğum üzerindeki etkisi. Zeynep Kamil Tıp Bülteni. 2010; 41(2): 59-63.
Vancouver Demirci O. , Bozoklu Ö. , Demirci E. , Tuğrul S. , Gürbüz A. , Eren S. , Çetiner H. Histolojik koioamnionitin erken doğum üzerindeki etkisi. Zeynep Kamil Tıp Bülteni. 2010; 41(2): 59-63.
IEEE O. Demirci , Ö. Bozoklu , E. Demirci , S. Tuğrul , A. Gürbüz , S. Eren and H. Çetiner , "Histolojik koioamnionitin erken doğum üzerindeki etkisi", Zeynep Kamil Tıp Bülteni, vol. 41, no. 2, pp. 59-63, Mar. 2010, doi:10.16948/zktb.54444