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Evaluation of myomectomy during cesarean section

Year 2015, Volume: 46 Issue: 3, 95 - 99, 16.03.2015

Abstract

Objective: In our research we aimed to evaluate intra-operative and post-operative risks and complications of myomectomy cases under the guidance of literature, during cesarean delivery in our clinic and we targeted to foresee the approach to recurring myoma cases.

Material- Methods: In our clinic between September 2010 and January 2014, data from 31 patients myomectomy during caesarean delivery (C/S) for relevant indications was compared retrospectively to the data of the control group consisting of 75 patients who only C/S. Placement, size and pathology reports of the myomas were recorded as well as the demographics characteristics of the patients. Groups were evaluated by the following parameters: Pre-operative and post-operative hemoglobin and hematocrit ,duration of the operation, hospitalization interval, return of bowel function, postoperative fever (>38oC), blood transfusion requirement, bleeding volume during operation (milliliters), pre or post-operative hysterectomy and follow up surgical intervention.

Results: There is no significant difference between the demographic characteristics of two groups in terms of age, gravidity, parity, gestational age and history. Neither of the groups have a statistically significant difference between pre-operative hemoglobin (Hb) and hematocrit (Hct) count. (p>0.05) Post-operative Hb and Hct median count was not statistical difference between two groups was observed. There was no difference between two groups for pre-operative bleeding amount. Research group of myomectomy cases had longer operation time and late return of bowel functions.  There was no significant difference between two groups for their duration of hospitalization interval.

Conclusion: There is no significant differences between patients who myomectomy during C/S and the control groups, except the operation time and later return of bowel functions. It was concluded that myomectomy during C/S would not cause any complications when if the patients are well assessed and the operation is carried on by an experienced surgeon. Extensive prospective studies with control groups are necessary for better assessment.

References

  • Baird DD, Dunson DB, Hill MC, Cousins D, Schectman JM. High cumulative incidence of uterine leiomyoma in black and white women: ultrasound evidence. Am J Obstet Gynecol 2003;188(1):100–7.
  • Laughlin SK, Baird DD, Savitz DA, Herring AH, Hartmann KE. Prevalence of uterine leiomyomas in the first trimester of pregnancy: an ultrasound-screening study. Obstet Gynecol 2009;113(3):630–5.
  • Qidwai GI, Caughey AB, Jacoby AF. Obstetric outcomes inwomenwith sonographically identified uterine leiomyomata. Obstet Gynecol 2006;107(2 Pt 1):376–82
  • Coleman-Cowger VH, Erickson K, Spong CY, Portnoy B, Croswell J, Schulkin J.Current practice of cesarean delivery on maternal request following the 2006state-of-the-science conference. J Reprod Med 2010;55(1–2):25–30
  • Baird DT, Collins J, Egozcue J, Evers LH, Gianaroli L, Leridon H, et al. Fertility and ageing. Hum Reprod Update 2005;11(3):261–76.
  • Leader A. Pregnancy and motherhood: The biological clock. Sex Reprod Menopause 2006;4(1):3–6.
  • Phelan JP. Myomas and pregnancy. Obstet Gynecol Clin North Am1995;22:801-5
  • Burton, C.A., D.A. Grimes & C.M. March. 1989. Surgical management of leiomyoma during pregnancy. Obstet. Gynecol. 74: 707–709
  • Lois, D. K. Zikopoulos & e. paraskevaidis. 1994. Surgical management of leiomyomata during pregnancy. Int. J. Obstet. Gynecol. 44: 71–72
  • Kwawukume EY. Caesarean myomectomy. Afr J Reprod Health 2002;6(3):38–43.
  • Roman AS, Tabsh KM. Myomectomy at time of cesarean delivery: a retrospective cohort study. BMC Pregnancy Childbirth 2004;4(1):14.
  • Sapmaz E, Celik H, Altungul A. Bilateral ascending uterine artery ligation vs. tourniquet use for hemostasis in cesarean myomectomy: a comparison. J Reprod Med. 2003;48:950–954.
  • Febo G, Tessarolo M, Leo L, Arduino S, Wierdis T, Lanza L. Surgical management of leiomyomata in pregnancy. Clin Exp Obstet Gynecol 1997;24(2):76–8.
  • Laughlin SK, Baird DD, Savitz DA, Herring AH, Hartmann KE. Prevalence of uterine leiomyomas in the first trimester of pregnancy: an ultrasound-screening study. Obstet Gynecol 2009;113(3):630-5.
  • Cooper NP, Okolo S. Fibroids in pregnancy common but poorly understood. Obstet Gynecol Surv 2005;60(2):132-8.
  • Gümüşburun T, Eyiceoğlu K, Boudnaon T, Göçkceoğlu MA, Topdağı İ. Myom ve gebelik. Atatürk Üniversitesi Tıp Fakültesi 1988;20(1): 95-9.
  • Song D, Zhang W, Chanes MC, Guo J. Myomectomy during cesarean delivery. Int J Gynaecol Obstet 2013;121(3):208-13.
  • Hasan F, Arumıgam K, Sivanesaratnam V. Uterine leiomyomata in pregnancy. Int J Gynecol Obstet 1990; 34:45-8.
  • Davis JL, Ray-Mazumder S, Hobel CJ, Baley K, Sassoon D. Uterine leiomyomas in pregnancy: a prospective study. Obstet Gynecol 1990;75(1):41-4
  • Lee JH, Cho DH. Myomectomy using purse-string suture during cesarean section. Arch Gynecol Obstet 2011;283(Suppl 1):35-7.
  • Song D, Zhang W, Chanes MC, Guo J. Myomectomy during cesarean delivery. Int J Gynaecol Obstet 2013;121(3):208-13
  • Tinelli A, Malvasi A, Mynbaev OA, Barbera A, Perrone E, Guido M, et al. The surgical outcome of intracapsular cesarean myomectomy: a match control study. J Matern Fetal Neonatal Med. 2014;27:66–71
  • Incebiyik A, Hilali NG, Camuzcuoglu A, Vural M, Camuzcuoglu H. Myomectomy during caesarean: a retrospective evaluation of 16 cases. Arch Gynecol Obstet 2014;289(3):569-73.
  • 24 )Ma CP, Juan YC, Wang ID, Chen CH, Liu WM, Jeng CJ. A huge leiomyoma subjected to a myomectomy during a cesarean section. Taiwan J Obstet Gynecol 2010;49 (2):220-1.
  • Roman AS, Tabsh KM. Myomectomy at time of cesarean delivery: a retrospective cohort study. BMC Pregnancy Childbirth 2004;4(1): 14.
  • Kwawukume EY. Myomectomy during cesarean section. Int J Gynaecol Obstet 2002; 76(2):183-4.
  • Park BJ, Kim YW. Safety of cesarean myo-mectomy. J Obstet Gynaecol Res 2009;35(5): 906-11.
  • Kwon D H, Song Ji E, Yoon K R, Lee K Y The safety of cesarean myomectomy in women with large myomas. Obstet Gynecol Science Sep 2014; 57(5): 367–372
  • Ortac F, Güngör M, Sönmezer M. Myomectomy during cesarean section. Int J Gynecol Obstet 1999;67(3):189-90.
  • Li H, Du J, Jin L, Shi Z, Liu M. Myomectomy during cesarean section. Acta Obstet Gynecol Scand 2009;88(2):183-6.

Sezeryan sırasında myomektomi yapılan olguların değerlendirilmesi

Year 2015, Volume: 46 Issue: 3, 95 - 99, 16.03.2015

Abstract

Amaç: Sezeryan sırasında myomektomi yapılan olguların literatür eşliğinde intraoperatif ve postoperatif risk ve komplikasyonlarını değerlendirerek bu olgulara yaklaşımı öngörebilmeyi amaçladık.

Gereç ve Yöntemler: Kliniğimizde eylül 2010- ocak 2014 yılları arasında çeşitli endikasyonlar ile sezeryan yapılan ve sezeryan sırasında myomektomi gerçekleştirilen 31 olgu ile sadece sezaryan yapılan 75 olgu retrospektif olarak değerlendirildi. Hastaların demografik özellikleri, myom sayı ve lokalizasyonu, myom boyutu ve histopatolojik sonuçları kaydedildi.

Preoperatif ve postoperatif hemoglobin(Hb) ve Hematokrit(Hct) değişimi, operasyon süresi hastanede kalış süresi, barsak fonksiyonlarının geri dönüş süresi, postoperatif ateş (>38C) kan transfüzyon ihtiyacı, kanama miktarı(mililitre), peroperatif ya da postoperatif histerektomiye gidiş, ek cerrahi girişim ihtiyacı açısından gruplar değerlendirildi.

Bulgular: İki grup arasında demografik özellikler (yaş, gravida, parite, gebelik haftası, geçirilmiş sezeryan öyküsü ) açısından anlamlı farklılık izlenmedi. Her iki grubun preoperatif Hb ve Hct değerleri arasında istatistiksel olarak anlamlı farklılık bulunmadı. Post operatif Hb ve Hct değerleri arasında iki grup arasında istatiksel fark izlenmedi.  İki grup arasında peroperatif kanama miktarı açısından fark izlenmedi. Myomektomi yapılan grupta operasyon süresi ve barsak fonksiyonlarının geri dönme süresi daha uzun bulundu. Hastanede kalış süreleri açısından iki grup arasında anlamlı farklılık izlenmedi.

Sonuç; Sezeryan esnasında myomektomi yapılan hastalarda ameliyat süresi ve barsak foksiyonlarının geri geliş süresi uzaması dışında kontrol gurubu arasında fark saptanmamıştır. Sezeryan esnasında myomektomi yapmak iyi değerlendirilmiş hastalarda ve deneyimli cerrahlarca uygulandığında ek bir komplikasyona yol açmadığı izlenmekte olup, konu ile ilgili daha fazla sayıda prospektif kontrol gruplu çalışmalara ihtiyaç vardır.

References

  • Baird DD, Dunson DB, Hill MC, Cousins D, Schectman JM. High cumulative incidence of uterine leiomyoma in black and white women: ultrasound evidence. Am J Obstet Gynecol 2003;188(1):100–7.
  • Laughlin SK, Baird DD, Savitz DA, Herring AH, Hartmann KE. Prevalence of uterine leiomyomas in the first trimester of pregnancy: an ultrasound-screening study. Obstet Gynecol 2009;113(3):630–5.
  • Qidwai GI, Caughey AB, Jacoby AF. Obstetric outcomes inwomenwith sonographically identified uterine leiomyomata. Obstet Gynecol 2006;107(2 Pt 1):376–82
  • Coleman-Cowger VH, Erickson K, Spong CY, Portnoy B, Croswell J, Schulkin J.Current practice of cesarean delivery on maternal request following the 2006state-of-the-science conference. J Reprod Med 2010;55(1–2):25–30
  • Baird DT, Collins J, Egozcue J, Evers LH, Gianaroli L, Leridon H, et al. Fertility and ageing. Hum Reprod Update 2005;11(3):261–76.
  • Leader A. Pregnancy and motherhood: The biological clock. Sex Reprod Menopause 2006;4(1):3–6.
  • Phelan JP. Myomas and pregnancy. Obstet Gynecol Clin North Am1995;22:801-5
  • Burton, C.A., D.A. Grimes & C.M. March. 1989. Surgical management of leiomyoma during pregnancy. Obstet. Gynecol. 74: 707–709
  • Lois, D. K. Zikopoulos & e. paraskevaidis. 1994. Surgical management of leiomyomata during pregnancy. Int. J. Obstet. Gynecol. 44: 71–72
  • Kwawukume EY. Caesarean myomectomy. Afr J Reprod Health 2002;6(3):38–43.
  • Roman AS, Tabsh KM. Myomectomy at time of cesarean delivery: a retrospective cohort study. BMC Pregnancy Childbirth 2004;4(1):14.
  • Sapmaz E, Celik H, Altungul A. Bilateral ascending uterine artery ligation vs. tourniquet use for hemostasis in cesarean myomectomy: a comparison. J Reprod Med. 2003;48:950–954.
  • Febo G, Tessarolo M, Leo L, Arduino S, Wierdis T, Lanza L. Surgical management of leiomyomata in pregnancy. Clin Exp Obstet Gynecol 1997;24(2):76–8.
  • Laughlin SK, Baird DD, Savitz DA, Herring AH, Hartmann KE. Prevalence of uterine leiomyomas in the first trimester of pregnancy: an ultrasound-screening study. Obstet Gynecol 2009;113(3):630-5.
  • Cooper NP, Okolo S. Fibroids in pregnancy common but poorly understood. Obstet Gynecol Surv 2005;60(2):132-8.
  • Gümüşburun T, Eyiceoğlu K, Boudnaon T, Göçkceoğlu MA, Topdağı İ. Myom ve gebelik. Atatürk Üniversitesi Tıp Fakültesi 1988;20(1): 95-9.
  • Song D, Zhang W, Chanes MC, Guo J. Myomectomy during cesarean delivery. Int J Gynaecol Obstet 2013;121(3):208-13.
  • Hasan F, Arumıgam K, Sivanesaratnam V. Uterine leiomyomata in pregnancy. Int J Gynecol Obstet 1990; 34:45-8.
  • Davis JL, Ray-Mazumder S, Hobel CJ, Baley K, Sassoon D. Uterine leiomyomas in pregnancy: a prospective study. Obstet Gynecol 1990;75(1):41-4
  • Lee JH, Cho DH. Myomectomy using purse-string suture during cesarean section. Arch Gynecol Obstet 2011;283(Suppl 1):35-7.
  • Song D, Zhang W, Chanes MC, Guo J. Myomectomy during cesarean delivery. Int J Gynaecol Obstet 2013;121(3):208-13
  • Tinelli A, Malvasi A, Mynbaev OA, Barbera A, Perrone E, Guido M, et al. The surgical outcome of intracapsular cesarean myomectomy: a match control study. J Matern Fetal Neonatal Med. 2014;27:66–71
  • Incebiyik A, Hilali NG, Camuzcuoglu A, Vural M, Camuzcuoglu H. Myomectomy during caesarean: a retrospective evaluation of 16 cases. Arch Gynecol Obstet 2014;289(3):569-73.
  • 24 )Ma CP, Juan YC, Wang ID, Chen CH, Liu WM, Jeng CJ. A huge leiomyoma subjected to a myomectomy during a cesarean section. Taiwan J Obstet Gynecol 2010;49 (2):220-1.
  • Roman AS, Tabsh KM. Myomectomy at time of cesarean delivery: a retrospective cohort study. BMC Pregnancy Childbirth 2004;4(1): 14.
  • Kwawukume EY. Myomectomy during cesarean section. Int J Gynaecol Obstet 2002; 76(2):183-4.
  • Park BJ, Kim YW. Safety of cesarean myo-mectomy. J Obstet Gynaecol Res 2009;35(5): 906-11.
  • Kwon D H, Song Ji E, Yoon K R, Lee K Y The safety of cesarean myomectomy in women with large myomas. Obstet Gynecol Science Sep 2014; 57(5): 367–372
  • Ortac F, Güngör M, Sönmezer M. Myomectomy during cesarean section. Int J Gynecol Obstet 1999;67(3):189-90.
  • Li H, Du J, Jin L, Shi Z, Liu M. Myomectomy during cesarean section. Acta Obstet Gynecol Scand 2009;88(2):183-6.
There are 30 citations in total.

Details

Primary Language Turkish
Journal Section OBSTETRICS AND GYNECOLOGY
Authors

Tülay Şahandar This is me

Meryem Eken

Emin Dönmez

Ebru Çöğendez

Taylan Şenol

Mustafa Eroğlu

Publication Date March 16, 2015
Published in Issue Year 2015 Volume: 46 Issue: 3

Cite

APA Şahandar, T., Eken, M., Dönmez, E., Çöğendez, E., et al. (2015). Sezeryan sırasında myomektomi yapılan olguların değerlendirilmesi. Zeynep Kamil Tıp Bülteni, 46(3), 95-99. https://doi.org/10.16948/zktb.03375
AMA Şahandar T, Eken M, Dönmez E, Çöğendez E, Şenol T, Eroğlu M. Sezeryan sırasında myomektomi yapılan olguların değerlendirilmesi. Zeynep Kamil Tıp Bülteni. October 2015;46(3):95-99. doi:10.16948/zktb.03375
Chicago Şahandar, Tülay, Meryem Eken, Emin Dönmez, Ebru Çöğendez, Taylan Şenol, and Mustafa Eroğlu. “Sezeryan sırasında Myomektomi yapılan olguların değerlendirilmesi”. Zeynep Kamil Tıp Bülteni 46, no. 3 (October 2015): 95-99. https://doi.org/10.16948/zktb.03375.
EndNote Şahandar T, Eken M, Dönmez E, Çöğendez E, Şenol T, Eroğlu M (October 1, 2015) Sezeryan sırasında myomektomi yapılan olguların değerlendirilmesi. Zeynep Kamil Tıp Bülteni 46 3 95–99.
IEEE T. Şahandar, M. Eken, E. Dönmez, E. Çöğendez, T. Şenol, and M. Eroğlu, “Sezeryan sırasında myomektomi yapılan olguların değerlendirilmesi”, Zeynep Kamil Tıp Bülteni, vol. 46, no. 3, pp. 95–99, 2015, doi: 10.16948/zktb.03375.
ISNAD Şahandar, Tülay et al. “Sezeryan sırasında Myomektomi yapılan olguların değerlendirilmesi”. Zeynep Kamil Tıp Bülteni 46/3 (October 2015), 95-99. https://doi.org/10.16948/zktb.03375.
JAMA Şahandar T, Eken M, Dönmez E, Çöğendez E, Şenol T, Eroğlu M. Sezeryan sırasında myomektomi yapılan olguların değerlendirilmesi. Zeynep Kamil Tıp Bülteni. 2015;46:95–99.
MLA Şahandar, Tülay et al. “Sezeryan sırasında Myomektomi yapılan olguların değerlendirilmesi”. Zeynep Kamil Tıp Bülteni, vol. 46, no. 3, 2015, pp. 95-99, doi:10.16948/zktb.03375.
Vancouver Şahandar T, Eken M, Dönmez E, Çöğendez E, Şenol T, Eroğlu M. Sezeryan sırasında myomektomi yapılan olguların değerlendirilmesi. Zeynep Kamil Tıp Bülteni. 2015;46(3):95-9.