Amaç: HELLP sendromu, maternal ve fetal iyilik durumunun hızlı şekilde bozulmasına neden olan, multisistemik bir hastalıktır Bu çalışmada, kliniğimizde HELLP sendromu tanısı konulan hastaların maternal ve fetal sonuçlarını analiz etmeyi amaçladık.
Yöntem: Bu çalışmada, kliniğimizde Ocak 2005 ile Aralık 2010 tarihleri arasında HELLP sendromu tanısı konulan 155 hastanın, hastane bilgisayar sistemindeki kayıtları geriye dönük olarak değerlendirildi. Hastaların demografik özellikleri, maternal ve perinatal sonuçlar, laboratuar parametreleri analiz edildi.
Bulgular: Hastaların yaş ortalaması 29,8 ± 6,9, ortalama gebelik haftası 31,4 ± 4,2 hafta, ortalama fetal ağırlık 1672,72 ± 726 gr olarak tespit edildi. Hastaların %61’ i multigravida, %39’u primigravida idi. En çok karşılaşılan maternal komplikasyonlar; 58 hastada (%37.4) transfüzyon ihtiyacı, 26 hastada (%16.8) akut böbrek yetmezliği, 11 hastada (%7.1) pulmoner ödem, 16 hastada (%10.3 ) DIC, 14 hastada (%9,1) dekolman plasenta, 10 hastada (%6.5) intrakranial kanama, 21 hastada (%13.5) mekanik ventilatör ihtiyacı idi. Prematürite oranı ise %83.4 olarak tespit edildi. 9 hastada (%12) perinatal mortalite gelişti.
Sonuç: HELLP sendromu maternal-fetal mortalite ve morbiditeyi artırmaktadır. Erken teşhis ve uygun tedavi HELLP sendromunun prognozunu belirlemede önemlidir.
Objective: HELLP syndrome is a
multisystem disorder which causes rapid deterioration of maternal and fetal
well-being. In this study, we aimed to investigate clinical and labaratory
parameters that influencing maternal and perinatal outcomes in addition to
relatonship between maternal and perinatal morbidity and mortalitiy in patients
which had been diagnosed as HELLP syndrome.
Material andMethod: In this study, the
hospital's computer system records of 155 patients diagnosed with HELLP
syndrome in our clinic between January 2005 and December 2010 were reviewed
retrospectively.The demographic characteristics of the patients, maternal and
perinatal outcomes and laboratory parameters were analyzed.
Results: The average age of the patients was 29,8 ±
6,9 year, the mean gestational age was 31,4 ± 4,2 week, the mean fetal birth weight was 1672,72±726 gr. Sixty-one percent of
patients were multigravida while 39% of
patients were primipar. The most common maternal complications were the
transfusion requirement in 58 patients (37,4%). We
found significant differences between patients who developed at least one
complications and no maternal complication with regard to AST, LDH, creatinine,
thrombocyte, and total bilirubine levels. Prematurity
rate was detected as 83,4%. Maternal mortality was occurred in 12 patients (7,7
%).Perinatal mortality was occurred in 9 patients (12 %).
Conclusion: HELLP syndrome increases
maternal-fetal morbidity and mortality. Early diagnosis and appropriate
treatment are important in determining the prognosis of HELLP syndrome.
Primary Language | Turkish |
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Subjects | Health Care Administration |
Journal Section | OBSTETRICS AND GYNECOLOGY |
Authors | |
Publication Date | December 27, 2016 |
Published in Issue | Year 2016 Volume: 47 Issue: 4 |