Objective: Rheumatoid heart disease (RHD) is an important
and preventable cause of cardiovascular disease in developing
countries. The aim of this study was to investigate the mean
platelet volume (MPV) and platelet distribution width (PDW)
in RHD.
Material and Methods: This study was carried out in Kayseri
Health Sciences University, Department of Pediatric Cardiology, with 135 children with RHD who were retrospectively
observed between February 2000 and February 2017 for seven
years and 40 healthy children with similar age and sex.
Results: The mean age of the 135 patients enrolled in the study
was 12,43 ± 3,11 years, 70 were males (51,8%) and 65 were
females (48,2%). The mean age of the control group was 12,96
± 2,55 years, 21,21 male (52,5%) and 19 female (47,5%). MPV
values of the patients were significantly lower in the RHD
group (9,43 ± 1,31 and 10,21 ± 1,25, p: 0,003).
Conversely, the PDW levels were significantly higher in the
RHD group (15,70 (15,40-16,00) and 12,25 (10,40-14,30), p:
0,001). When MPV / PDW ratio was examined, it was found to
be significantly lower in the RHD group (0,61 (0,55-0,71) and
0,87 (0,79-0,93), p: 0,001).
Conclusion: MPV values were lower and PDW values were higher when compared to controls in RHD process.
Primary Language | Turkish |
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Subjects | Health Care Administration |
Journal Section | Original Research |
Authors | |
Publication Date | March 5, 2018 |
Published in Issue | Year 2018 Volume: 49 Issue: 1 |