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EARLY ONSET HELLP SYNDROME WITH SYSTEMİC LUPUS ERYTEMATOSUS AND ACUTE CHOLECYSTİTİS ATTACK AT 17TH WEEK OF GESTATİON

Year 2020, Volume 51, Issue 1, 46 - 48, 15.01.2020
https://doi.org/10.16948/zktipb.492975

Abstract

Hellp syndrome is an atypic, severe and life threatening form of preeclapmsia, which is usually associated with hemolysis, elevated liver enzymes and low platelet count. Also it is very important because it causes significantly maternal and perinatal mortality. It is known that hellp syndrome almost always occurs after 20 weeks of gestation. But in the presence of some accompanying diseases, hellp syndrome or severe preeclampsia can occur at earlier gestational weeks. This may also lead to diagnostic difficulties. In this case, we described the diagnosis and recovery period of a systemic lupus erytematosus (SLE) patient who developed hellp syndrome at 17 weeks of gestation. Our experience takes attention that detection of hellp syndome accompanying diseases like systemic lupus erytematosus or acute cholecystitis can be difficult and it can occur distinctly at earlier weeks of gestation. Also the differential diagnosis is very important in such cases, because many diseases can mimic hellp syndrome.

References

  • 1) Sibai BM. Diagnosis, controversies, and management of the syndrome of hemolysis, elevated liver enzymes, and low platelet count. Obstet Gynecol. 2004;103(5 Pt 1):981.
  • 2) Dusse LM, Alpoim PN, Silva JT, Rios DR, Brandão AH, Cabral AC. Revisiting HELLP syndrome. Clin Chim Acta. 2015; 451:117.
  • 3) Stefos T, Plachouras N, Mari G, Cosmi E, Lolis D. A case of partial mole and atypical type I triploidy associated with severe HELLP syndrome at 18 weeks' gestation. Ultrasound in Obstetrics and Gynecology. 2002; Volume 20, Issue 4
  • 4) Sibai BM, Ramadan MK, Usta I, Salama M, Mercer BM, Friedman SA. Maternal morbidity and mortality in 442 pregnancies with hemolysis, elevated liver enzymes, and low platelets (HELLP syndrome). Am J Obstet Gynecol. 1993;169(4):1000.
  • 5) Oostwaard MF, Ferden L, Laat MW, Duvekot JJ, Erwich JJHM, Bloemenkamp KWM, Bolte AC, Bosma JPF, Koenen SV, Kornelisse RF, Rethans B, Heimel Runnard P, Scheepers HCJ, Ganzevoort W, Mol BWJ, Groot CJ, Gaugler-Seden IPM. Maternal and neonatal outcomes in women with severe early onset pre‐eclampsia before 26 weeks of gestation, a case series. BJOG: An International Journal of Obstetrics & Gynaecology. Volume 124, Issue 9.
  • 6) Rahman TM, Wendon J. “Severe hepatic dysfunction in pregnancy,” Monthly Journal of the Association of Physicians. 2002; vol. 95, no. 6, pp. 343–357.
  • 7) Wada Y, Sakamaki Y, Kobayashi D, Ajiro J, Moro H, Murakami S, Ooki I, Kikuchi A, Takakuwa K, Tanaka K, Sato T, Nakano M, Narita I. HELLP syndrome, multiple liver infarctions, and intrauterine fetal death in a patient with systemic lupus erythematosus and antiphospholipid syndrome. Intern Med. 2009;48(17):1555-8. Epub 2009 Sep 1.
  • 8) S. Appenzeller, F. H. Souza, A. Wagner Silvia de Souza, Y. Shoenfeld, and J. F. de Carvalho, “HELLP syndrome and its relationship with antiphosphplipid syndrome and antiphospholipid antibodies,” Seminars in Arthritis and Rheumatism. 2011; vol. 41, pp. 517–523.
  • 9) Suzumori N, Obayashi S, Kumagai K, Goto S, Yoshida A, Sugiura-Ogasawara M. Case Rep Med. A Case of Microangiopathic Antiphospholipid-Associated Syndromes during Pregnancy: Review of the Literature. 2012; 2012:827543. doi: 10.1155/2012/827543. Epub 2012 Jun 28.
  • 10) Haram K, Trovik J, Sandset PM, Hordnes K. Severe syndrome of hemolysis, elevated liver enzymes and low platelets (HELLP) in the 18th week of pregnancy associated with the antiphospholipid–antibody syndrome. Acta Obstetricia et Gynecologica Scandinavica.2003; Volume 82, Issue 7 .

17. gebelik haftasında akut kolesistit atağı ve sistemik lupus eritematozus ile birlikte görülen erken başlangıçlı hellp sendromu

Year 2020, Volume 51, Issue 1, 46 - 48, 15.01.2020
https://doi.org/10.16948/zktipb.492975

Abstract

Hellp sendromu, preeklampsinin atipik, şiddetli ve hayatı tehdit eden bir formu olup genellikle hemoliz, yüksek karaciğer enzimleri ve düşük platelet düzeyleri ile ilişkilidir. Ayrıca, belirgin maternal ve perinatal mortaliteye de neden olduğundan önemi büyüktür. Hellp sendromunun hemen her zaman gebeliğin 20. haftadan önce meydana geldiği bilinmektedir. Fakat bazı eşlik eden hastalıkların varlığında hellp sendromu veya şiddetli preeklampsi daha erken gebelik haftalarında da görülebilir. Bu durum aynı zamanda tanısal zorluğa da neden olur. Biz bu olguda, 17. Gebelik haftasında hellp sendromu gelişen bir sistemik lupus eritematozus (SLE) hastasının tanı ve tedavi periodunu anlattık. Çalışmamız; hellp sendromunun SLE ya da akut kolesistit gibi eşlik eden hastalıklar varlığında tespit edilmesinin zorluğuna ve şaşırtıcı olarak erken gebelik haftalarında meydana gelebilmesine dikkat çekmektedir. Aynı zamanda, böyle olgularda, birçok hastalık hellp sendromunu taklit edebileceğinden ayırıcı tanı da çok önemlidir.

References

  • 1) Sibai BM. Diagnosis, controversies, and management of the syndrome of hemolysis, elevated liver enzymes, and low platelet count. Obstet Gynecol. 2004;103(5 Pt 1):981.
  • 2) Dusse LM, Alpoim PN, Silva JT, Rios DR, Brandão AH, Cabral AC. Revisiting HELLP syndrome. Clin Chim Acta. 2015; 451:117.
  • 3) Stefos T, Plachouras N, Mari G, Cosmi E, Lolis D. A case of partial mole and atypical type I triploidy associated with severe HELLP syndrome at 18 weeks' gestation. Ultrasound in Obstetrics and Gynecology. 2002; Volume 20, Issue 4
  • 4) Sibai BM, Ramadan MK, Usta I, Salama M, Mercer BM, Friedman SA. Maternal morbidity and mortality in 442 pregnancies with hemolysis, elevated liver enzymes, and low platelets (HELLP syndrome). Am J Obstet Gynecol. 1993;169(4):1000.
  • 5) Oostwaard MF, Ferden L, Laat MW, Duvekot JJ, Erwich JJHM, Bloemenkamp KWM, Bolte AC, Bosma JPF, Koenen SV, Kornelisse RF, Rethans B, Heimel Runnard P, Scheepers HCJ, Ganzevoort W, Mol BWJ, Groot CJ, Gaugler-Seden IPM. Maternal and neonatal outcomes in women with severe early onset pre‐eclampsia before 26 weeks of gestation, a case series. BJOG: An International Journal of Obstetrics & Gynaecology. Volume 124, Issue 9.
  • 6) Rahman TM, Wendon J. “Severe hepatic dysfunction in pregnancy,” Monthly Journal of the Association of Physicians. 2002; vol. 95, no. 6, pp. 343–357.
  • 7) Wada Y, Sakamaki Y, Kobayashi D, Ajiro J, Moro H, Murakami S, Ooki I, Kikuchi A, Takakuwa K, Tanaka K, Sato T, Nakano M, Narita I. HELLP syndrome, multiple liver infarctions, and intrauterine fetal death in a patient with systemic lupus erythematosus and antiphospholipid syndrome. Intern Med. 2009;48(17):1555-8. Epub 2009 Sep 1.
  • 8) S. Appenzeller, F. H. Souza, A. Wagner Silvia de Souza, Y. Shoenfeld, and J. F. de Carvalho, “HELLP syndrome and its relationship with antiphosphplipid syndrome and antiphospholipid antibodies,” Seminars in Arthritis and Rheumatism. 2011; vol. 41, pp. 517–523.
  • 9) Suzumori N, Obayashi S, Kumagai K, Goto S, Yoshida A, Sugiura-Ogasawara M. Case Rep Med. A Case of Microangiopathic Antiphospholipid-Associated Syndromes during Pregnancy: Review of the Literature. 2012; 2012:827543. doi: 10.1155/2012/827543. Epub 2012 Jun 28.
  • 10) Haram K, Trovik J, Sandset PM, Hordnes K. Severe syndrome of hemolysis, elevated liver enzymes and low platelets (HELLP) in the 18th week of pregnancy associated with the antiphospholipid–antibody syndrome. Acta Obstetricia et Gynecologica Scandinavica.2003; Volume 82, Issue 7 .

Details

Primary Language English
Subjects Health Care Sciences and Services
Journal Section Case Report
Authors

Gamze Nur CİMİLLİ ŞENOCAK> (Primary Author)
atatürk üniversitesi
0000-0002-6750-9210
Türkiye

Publication Date January 15, 2020
Published in Issue Year 2020, Volume 51, Issue 1

Cite

Bibtex @case report { zktipb492975, journal = {Zeynep Kamil Tıp Bülteni}, issn = {1300-7971}, eissn = {2148-4864}, address = {}, publisher = {Zeynep Kamil Kadın ve Çocuk Hastalıkları EAH}, year = {2020}, volume = {51}, number = {1}, pages = {46 - 48}, doi = {10.16948/zktipb.492975}, title = {EARLY ONSET HELLP SYNDROME WITH SYSTEMİC LUPUS ERYTEMATOSUS AND ACUTE CHOLECYSTİTİS ATTACK AT 17TH WEEK OF GESTATİON}, key = {cite}, author = {Cimilli Şenocak, Gamze Nur} }
APA Cimilli Şenocak, G. N. (2020). EARLY ONSET HELLP SYNDROME WITH SYSTEMİC LUPUS ERYTEMATOSUS AND ACUTE CHOLECYSTİTİS ATTACK AT 17TH WEEK OF GESTATİON . Zeynep Kamil Tıp Bülteni , 51 (1) , 46-48 . DOI: 10.16948/zktipb.492975
MLA Cimilli Şenocak, G. N. "EARLY ONSET HELLP SYNDROME WITH SYSTEMİC LUPUS ERYTEMATOSUS AND ACUTE CHOLECYSTİTİS ATTACK AT 17TH WEEK OF GESTATİON" . Zeynep Kamil Tıp Bülteni 51 (2020 ): 46-48 <https://dergipark.org.tr/en/pub/zktipb/issue/52318/492975>
Chicago Cimilli Şenocak, G. N. "EARLY ONSET HELLP SYNDROME WITH SYSTEMİC LUPUS ERYTEMATOSUS AND ACUTE CHOLECYSTİTİS ATTACK AT 17TH WEEK OF GESTATİON". Zeynep Kamil Tıp Bülteni 51 (2020 ): 46-48
RIS TY - JOUR T1 - EARLY ONSET HELLP SYNDROME WITH SYSTEMİC LUPUS ERYTEMATOSUS AND ACUTE CHOLECYSTİTİS ATTACK AT 17TH WEEK OF GESTATİON AU - Gamze Nur Cimilli Şenocak Y1 - 2020 PY - 2020 N1 - doi: 10.16948/zktipb.492975 DO - 10.16948/zktipb.492975 T2 - Zeynep Kamil Tıp Bülteni JF - Journal JO - JOR SP - 46 EP - 48 VL - 51 IS - 1 SN - 1300-7971-2148-4864 M3 - doi: 10.16948/zktipb.492975 UR - https://doi.org/10.16948/zktipb.492975 Y2 - 2018 ER -
EndNote %0 Medical Bulletin of Zeynep Kamil EARLY ONSET HELLP SYNDROME WITH SYSTEMİC LUPUS ERYTEMATOSUS AND ACUTE CHOLECYSTİTİS ATTACK AT 17TH WEEK OF GESTATİON %A Gamze Nur Cimilli Şenocak %T EARLY ONSET HELLP SYNDROME WITH SYSTEMİC LUPUS ERYTEMATOSUS AND ACUTE CHOLECYSTİTİS ATTACK AT 17TH WEEK OF GESTATİON %D 2020 %J Zeynep Kamil Tıp Bülteni %P 1300-7971-2148-4864 %V 51 %N 1 %R doi: 10.16948/zktipb.492975 %U 10.16948/zktipb.492975
ISNAD Cimilli Şenocak, Gamze Nur . "EARLY ONSET HELLP SYNDROME WITH SYSTEMİC LUPUS ERYTEMATOSUS AND ACUTE CHOLECYSTİTİS ATTACK AT 17TH WEEK OF GESTATİON". Zeynep Kamil Tıp Bülteni 51 / 1 (January 2020): 46-48 . https://doi.org/10.16948/zktipb.492975
AMA Cimilli Şenocak G. N. EARLY ONSET HELLP SYNDROME WITH SYSTEMİC LUPUS ERYTEMATOSUS AND ACUTE CHOLECYSTİTİS ATTACK AT 17TH WEEK OF GESTATİON. Zeynep Kamil Tıp Bülteni. 2020; 51(1): 46-48.
Vancouver Cimilli Şenocak G. N. EARLY ONSET HELLP SYNDROME WITH SYSTEMİC LUPUS ERYTEMATOSUS AND ACUTE CHOLECYSTİTİS ATTACK AT 17TH WEEK OF GESTATİON. Zeynep Kamil Tıp Bülteni. 2020; 51(1): 46-48.
IEEE G. N. Cimilli Şenocak , "EARLY ONSET HELLP SYNDROME WITH SYSTEMİC LUPUS ERYTEMATOSUS AND ACUTE CHOLECYSTİTİS ATTACK AT 17TH WEEK OF GESTATİON", Zeynep Kamil Tıp Bülteni, vol. 51, no. 1, pp. 46-48, Jan. 2020, doi:10.16948/zktipb.492975