Tekiz gebeliklerde birinci trimester intrakranial translusensi nomogramı

Year 2020, Volume: 51 Issue: 1, 5 - 8, 15.01.2020

Fatih Şanlıkan Resul Arisoy Koray Özbay Altuğ Semiz

https://doi.org/10.16948/zktipb.685282

Abstract

Tekiz gebeliklerde birinci trimester intrakranial translusensi nomogramı
Özet
Amaç:11-14. gebelik haftaları için intrakranial translusensi (IT) nomogramı oluşturulması ve IT ölçümlerinin gebelik günleri, baş popo mesafesi ve bipariyatel çap ile olan ilişkisinin değerlendirilmesi.
Gereçler ve Yöntem: Kliniğimize başvuran birinci trimester’deki 119 tekiz gebe çalışmaya dâhil edildi, bu gebelerde fetüslerin IT genişliği değerlendirilip gebelik günü, b aş popo mesafesi (CRL) ve bipariyatel çap (BPD)ile olan ilişkisi araştırıldı. Yapısal veya kromozomal anomali saptanan fetüsler ve çoğul gebelikler çalışma dışı bırakıldı.
Bulgular: Çalışmamızda ortalama gebelik günü 86,6 ± 4,9, CRL 61,6 ± 7,2 mm, BPD 20,7 ± 2,3 mm, IT genişliği 1,7 ± 0,3 mm olarak tespit edildi. 11-14. gebelik haftaları için gebelik günlerine göre IT nomogramı oluşturuldu. Lineer regresyon analizinde IT ile gebelik günü, CRL ve BPD arasında zayıf pozitif korelasyon saptandı (sırasıyla r=0.30, r2=0,0899, r2 =0,0815). IT genişliğinin 50.persentil değeri 11 hafta 0-6 gün, 12 hafta 0-6 gün ve 13 hafta 0-6 gün için sırasıyla 1,5 mm, 1,7 mm ve 1,8 mm olarak saptandı.
Sonuç: Birinci trimesterde nuchal tranlusensi ölçümleri yapılırken eş zamanlı olarak kolaylıkla ölçülebilen IT, santral sinir sistemi anomalilerinin saptanmasında faydalı olabilen bir ölçümdür. Çalışmamızın sonuçları literatürü destekleyecek şekilde, IT’nin ilerleyen gebelik haftalarıyla beraber lineer olarak arttığını ve gebelik günleri, CRL ve BPD ile korele olduğunu göstermiştir. Elde ettiğimiz IT nomogramı kendi popülasyonumuzun değerlendirilmesinde faydalı olabilir.
Anahtar Kelimeler: İntrakranial translusensi, birinci trimester, nomogram

First trimester intracranial translucency nomogram in singleton pregnancies
Abstract
Objective: Our aim was to create an intracranial translucency (IT) nomogram for the 11-14 weeks of gestation and to evaluate the relationships between IT measurements and gestational days, crown rump length and biparietal diameter.
Material and Methods: 119 singleton pregnant women who applied to our clinic in the first trimester were included in the study. The IT of the fetuses were evaluated and the relationship between IT measurements and gestational day, crown rump length (CRL) and biparietal diameter (BPD) was investigated.
Results: We determined the mean values for gestational day, CRL, BPD and IT as 86.6 ± 4.9 days, 61.6 ± 7.2 mm, 20.7 ± 2.3 mm1.7 ± 0.3 mm, respectively. After then an IT nomogram was formed according to pregnancy days for the11-14gestational weeks. Linear regression analysis revealed a weak positive correlation between IT and gestational day, CRL and BPD (r= 0.30, r2= 0.0899, r2= 0.0815, respectively).The 50th percentile value of IT was determined as 1.5 mm, 1.7 mm and 1.8 mm for 11 weeks 0-6 days, 12 weeks 0-6 days and 13 weeks 0-6 days, respectively.
Conclusion: IT can be easily measured simultaneously while performing nuchal translucency measurements in the first trimester, which can be useful in detecting central nervous system anomalies. The results of our study showed that IT increased linearly with advancing gestational weeks and correlated with gestational days, CRL and BPD, in accordance with the literature. The IT nomogram we obtained can be useful in evaluating our own population.
Keywords: Intracranial translucency, first trimester, nomogram

Keywords

İntrakranial translusensi, birinci trimester, nomogram

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