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İÇSULARDA SİYANOBAKTERİ ARTIŞLARI VE OLUŞTURDUĞU RİSKLER

Year 2019, Issue: 367, 25 - 35, 26.09.2019
https://doi.org/10.33724/zm.562579

Abstract

Siyanobakterilerin
aşırı çoğalmaları sıklığı giderek artan ve tüm su kaynaklarını tehdit eden önemli
bir sorundur. Su kütlelerinde organik kirlenme sonucu oluşan ötrofikasyon göl
ve baraj göllerinin su kalitesinin bozulmasına ve siyanobakteriyel artışların
oluşumuna ortam hazırlamaktadır. İnsanlarda çeşitli hastalıklara, kuş ve sucul
canlılarda ölümlere sebep olan toksin üreticisi 40 farklı siyanobakteri türü
bilinmektedir. Bu toksinler etkilerine göre hepatotoksin, nörotoksin ve
dermatotoksinler olarak ayrılmaktadır. Bu derlemede, siyanobakterilerin aşırı
artışları ve içsularda oluşturduğu riskler tartışılacaktır.

References

  • 1- Weis Y.H., C.Y. Pang., 2010. The Role of Mitocondria in human aging process. Biotech International, 17: 8-13. Wiese, M., D’Agostino, P.M., Mihali, T. K., Moffitt, M. C. And Neilan, B. A., Neurotoxic Alkaloids: Saxitoxin and Its Analogs, Marine Drugs, 8: 2185- 2211.
  • 2- Hitzfeld, B., Lampert, C., Späth, N., Mountfort, D., Kaspar, H., Dietrich, D., 2000. Toxin production in cyanobacterial mats from ponds on the McMurdo Ice Shelf, Antarctica. Toxicon, (38), 1731-1748.
  • 3- Reynolds C.S., and Walsby A.E., 1975. Water Blooms. Biol Rev 50 437-481.
  • 4- Carmicheal, W.W., 1992. Cyanobacteria secondary metabolites—the cyanotoxins, Journal of Applied Bacteriology, 72,445–459.
  • 5- Carmicheal, W.W., 1994. The toxins of cyanobacteria, Scientific American, 270, 78–86.
  • 6- Falconer, I.R., Hardy, S.J., Humpage, A.R., Froscio, S M., Tozer, G.J., Hawkins, P.R., 1999. Hepatic and renal toxicity of the blue-green alga (cyanobacterium) Cylindrospermopsis raciborskii in male Swiss Albino mice. J. Environ. Toxicol. Water Qual., (14), 1.
  • 7- Madigan, T.M., Martinko, J. M., Stahl, D. A., Clark, D. P., 2012. Brock biology of microorganisms. Thirteen edition.
  • 8- Chorus, I., and Bartram, J., 1999. Toxic cyanobacteria in water: A guide to their public health consequences, monitoring and management. E & FN Spon, London, WHO, p. 400. Geneva.
  • 9- Mur, L.R., O.M.Skulberg, et al., 1999. Cyanobacteria in the environment. Toxic Cyanobacteria in Water: A Guide to Their Public Health Consequences, Monitoring ans Management. I. Chorus and J.Bartram, eds. London, E and FN Spon (on behalf of WHO):15-40.
  • 10- Whitton, B. A., 2000. Soils and rice-fields. In Whitton, B.A., Potts M. (eds), The Ecology of Cyanobacteria, Kluwer Academic, Dordrecht, pp. 233–255.
  • 11- Duy, T.N., Lam, P.K.S., Shaw, G.R., Connel, D.W., 2000. Toxicology and risk assessment of freshwater cyanobacterial (blue-green algal) toxins in water’. Rev Environ Contam Toxicol, 163, 113-186.
  • 12- Nichols, J.M., Adams, D.J., Carr, N.G., Whitton, B.A., 1982. Akinetes, The Biology Of Cyanobacteria, Blackwell Scientific Publications, Oxford, 378-412.
  • 13- Walsby, A.E., 1987. Mechanisms of buoyancy regulation by planktonic Cyanobacteria with gas vesicles. In: P. Fay and C. Van Baalen (eds) The Cyanobacteria. Elsevier, Amsterdam, 377-414.
  • 14- Güner, H. ve Aysel, V., 2006. Tohumsuz Bitkiler Sistematiği, Cilt 1 (Algler), Ege Üniversitesi Fen Fakültesi Yayınları, Altıncı Baskı, 245s.
  • 15- Chorus, I., 2001. ‘’Cyanotoxins: occurrence, causes, consequence’’, Springer, Heidelberg, Germany.
  • 16- NRA, 1990. Toxic Blue Green Algae. Water Quality Series No.2 National Rivers Authority, pp. 125. London.
  • 17- Carmichael, W.W., Falconer, I.R., 1993. Diseases Related to Freshwater Blue Green Algal Toksins ve Control Measures. In Algal Toksins in Seefood ve Drinking Water Falconer, I.R. (ed) London Academic Press.
  • 18- Codd, G.A., Azevedo, S.M.F.O., Bagchi, S.N., Burch, M.D., Carmichael, W.W., Harding, W.R., Kaya, K. and Utkilen, H.C., 2005. Cyanonet A Global Network for Cyanobacterial Bloom and Toxin Risk Management. The International Hydrological Programme (IHP) of the United Nations Educational, Scientific and Cultural Organization (UNESCO), p. 141. France.
  • 19- Negri, A.P., Jones, G.J., Hindmarsh, M., 1995. Sheep mortality associated with paralytic shellfish poisons from the cyanobacterium Anabaena circinalis, Toxicon, 33:1321-1329.
  • 20- Falconer, I.R., 2001. Toxic Cyanobacteria Bloom Problems in Australian Water: Risks and impacts on Human Health, Phycologia, 40, 228-233.
  • 21- Svircˇev, Z., Baltic´ , V., Miladinov-Mikov, M., Sajenkovic´, D., 2011. Cyanobacterial blooms in Serbia epidemiological studies and health risk assessment, In: 16th Academy of Studenica – International Scientific Conference Cyanobacteria and human health. Novi Sad. Abstract Book, p. 34.
  • 22- Eriksson, J.E., Hagerstrand, H., Isomaa, B., 1987. Cell selective cytotoxicity of a peptide toxin from the cyanobacterium Microcystis aeruginosa, Biochim Biophys Acta, 930(2), 304-310.
  • 23- Runnegar, M., Berndt, N.; Kaplowitz, N., 1995a. Mikrosistin uptake and inhibition of protein phosphatases: effects of chemoprotectants and self-inhibition in relation to known hepatic transporters, Toxicol. App. Pharmacol., 134, 264-72.
  • 24- Fujiki, H., Suganuma, M., 1993. Tumor promotion by inhibitors of protein phosphatases 1 and 2A: the okadaic acid class of compounds. Adv. Cancer Res., (61), 143-194.
  • 25- Harada, K-I., 1996. Chemistry and Detection of Mikrosistins, In: Toxic Microcystis, (M.F. Watanabe, K-I. Harada, W.W. Carmichael and H. Fujiki eds) Chemical Rubber Company (CRC) Press, pp. 103-148. Boca Raton, Florida.
  • 26- Metcalf, J.S., Keneth, A.B., Plugmacher, S., Codd, G.A., 2000. Immunocrossreactivity ve Toxicity assesment of Conjugation Products of the Cyanobacterial toxin, Mikrosistin-LR. FEMS Microbiology Letters, (189), 155-158.
  • 27- Hoeger, S.J., Dietrich, D.R., Hitzfeld, B.C., 2002. Effect of Ozonation on the Removal of Cyanobacterial Toxins during Drinking Water Treatment Environ Health Perspect, (110), 1127–1132.
  • 28- Kellmann, R., Neilan, B. A., 2007, Biochemical characterization of paralytic shellfish toxin biosynthesis in vitro. J. Phycol., 43,497–508.
  • 29- Hawkins, P.R., Chverasena, N.R., Jones, G.J., Humpage, A.R., Falconer, I.R., 1997. Isolation ve toxicity of Cylindrospermopsis raciborskii from an ornamental lake. Toxicon, 35, (3), 341-346.
  • 30- Kiss, T., Vehovszky, A., Hiripi, L., Kovacs, A., Voros, L., 2002. Membrane effects of toxins isolated from a cyanobacterium, Cylindrospermopsis raciborskii, on identified molluscan neurones, Comp. Biochem. Physiol. Part C, 131,167–176.
  • 31- Aykulu, G., Obalı, O., 1981. Phytoplankton biomass in the Kurtboğazı Dam Lake. Communications de la Faculté des sciences de l'Université d'Ankara: Botanique, Serie C2, 24:29-45.
  • 32- Obalı, O., 1984. Mogan gölü fitoplanktonunun mevsimsel değişimi. Doğa Bilim Dergisi, 8(1): 91–104.
  • 33- Cirik, S., Cirik, Ş., 1989. Gölcük'ün (Bozdağ/İzmir) Planktonik Algleri. İ.Ü. Su Ürün.Derg., Cilt: 3, Sayı 1-2: 131-150, İstanbul.
  • 34- Aykulu, G., Doğan, K., Hasırcı, S., 1999. Phytoplankton communities of the lakes Taşkısığı and Poyrazlar (Adapazarı, Turkey). İstanbul Üniversitesi Su Ürünleri Dergisi, Özel Sayı, 157 - 184.
  • 35- Albay, M., Akçaalan, R., Aykulu, G., Tüfekçi, H., Beattie, K.A., Codd, G.A., 2003. Occurence of toxic cyanobacteria before and after copper sulphate treatment in a water reservior, İstanbul, Turkey, Algological Studies 109,67-68.
  • 36- Albay, M., Akçaalan, R., Köker, L., Gurevin, C., 2014. Planktothrix rubescens: A perennial presence and toxicity in Lake Sapanca. Turkish Journal of Botany, 38:782-789.
  • 37- Albay, M., Matthiensen, A., Cood, G., 2005. Occurrence of toxic blue-green algae in the Kucukcekmece Lagoon (Istanbul, Turkey). Environmental Toxicology 20(3):277-84.
  • 38- Demir, N., 2007. Changes in the phytoplankton community of a coastal, hyposaline lake in western Anatolia, Turkey. Limnology, 8:337–342.
  • 39- Kızılkaya, I,T., Demirel, Z., Kesici, K., Kesici, E., Sukatar, A., 2016. Morphological, Molecular and Toxicologial Characterization of Nodularia spumigena Mertens in Jungens (1822) from Brackishwater Lake Bafa (Turkey). Sinop Uni. J. Nat. Sci. 1(1): 39-52.
  • 40- Akçaalan, R., Köker, L., Oğuz, A., Albay, M., 2014. First Report of Cylindrospermopsin Production by Two Cyanobacteria (Dolichospermum mendotae and Chrysosporum ovalisporum) in Lake Iznik, Turkey. Toxins 6(11):3173-3186.
  • 41- Albay, M., Akçaalan, R., Köker, L., 2016. Do Eutrophic Waters Prompt to Toxic Cyanobacteria in Turkish Black Sea Coast?. Journal of environmental protection and ecology 17(2):584-592.
  • 42- Köker, L., Akçaalan, R., Albay, M., Neilan, B., 2017. Molecular detection of hepatotoxic cyanobacteria in inland water bodies of the Marmara Region, Turkey. Advances in Oceanography and Limnology,8(1).
  • 43- Yılmaz, M., Foss, A,J., Miles, C,O., Özen, M., Balcı, M., Demir, N., Beach, D.G. Hing, 2018. Diversity of Microcystins in a Microcystis aeruginosa Isolate from Lake Uluabat. 13th International Symposium on Fisheries and Aquatic Sciences Proceding Book ISBN: 978-605-68894-0-0 Publication of e-book date: 17.12.2018.
  • 44- Koker, L., Akçaalan, A., Oguz, A., Gaygusuz, O., Gurevin, C., Akat Kose, C., Gucver, S., Karaaslan,Y., Erturk, A., Albay, M., Kınacı, C., 2017. Distribution of Toxic Cyanobacteria and Cyanotoxins in Turkish Waterbodies. Journal of Environmental Protection and Ecology 18, 425-432.
  • 45- Tisdale, E.S., 1931. Epidemic of intestinal disorders in Charleston, W. VA., Occurring simultaneously with unprecedented water supply conditions. American Journal of Public Health, (21), 198-200.
  • 46- Zilberg, B., 1966. Gastroenteritis in Salisbury European children-a five-year study. The Central African Journal of Medicine, (12), 164-168.
  • 47- Botes, D.P., Tuinman, A.A., Wessels, P.L., Viljoen, C.C., Kruger, H., Williams, D.H. Santikarn, S., 1984. The Structure of Cyanoginosin-LA, A Cyclic Heptapeptide Toxin From The Cyanobacterium Microcystis Aeruginosa. J. Chem. Soc., Perkin Transactions, (1), 2311-2318.
  • 48- Teixera, M.G.L.C., Costa, M.C.N., Carvalho, V.L.P., Pereira, M.S., Hage, E., 1993. Gastroenteritis epidemic in the area of the Itaparica Dam, Bahia, Brazil. Bulletin of the Pan American Health Organization, (27), 244-253.
  • 49- Byth, S., 1980. Palm Island mystery disease, Med. J. Aust., 2,40-42.
  • 50- Pouria, S.A., Barbosa, J., Cavalcanti, R.L., Barreto, V.T.S., Ward, C.J., Preiser, W., Poon, G.K., Neild, G.H., Codd, G.A., 1998. Fatal Mikrosistin intoxication in haemodialysis unit in Caruaru, Brazil. The Lancet, 352: 21-25.

CYANOBACTERIAL BLOOMS AND THEIR RISKS IN FRESHWATERS

Year 2019, Issue: 367, 25 - 35, 26.09.2019
https://doi.org/10.33724/zm.562579

Abstract

Cyanobacterial blooms are increasing frequency and threatening water
sources worldwide. Eutrophication caused by organic pollution in water bodies provides
an environment for the deterioration of water quality and the formation of cyanobacterial
increases in lakes and reservoirs. 40 species of cyanobacteria are known as
producers of some toxins responsible for a wide array of health problems,
dangerous for aquatic organisms and responsible for bird kills. These toxins
are divided as hepatotoxin, neurotoxin and dermatotoxins according to their
effects. In this review, cyanobacterial blooms and risks in inland waters will
be discussed.

References

  • 1- Weis Y.H., C.Y. Pang., 2010. The Role of Mitocondria in human aging process. Biotech International, 17: 8-13. Wiese, M., D’Agostino, P.M., Mihali, T. K., Moffitt, M. C. And Neilan, B. A., Neurotoxic Alkaloids: Saxitoxin and Its Analogs, Marine Drugs, 8: 2185- 2211.
  • 2- Hitzfeld, B., Lampert, C., Späth, N., Mountfort, D., Kaspar, H., Dietrich, D., 2000. Toxin production in cyanobacterial mats from ponds on the McMurdo Ice Shelf, Antarctica. Toxicon, (38), 1731-1748.
  • 3- Reynolds C.S., and Walsby A.E., 1975. Water Blooms. Biol Rev 50 437-481.
  • 4- Carmicheal, W.W., 1992. Cyanobacteria secondary metabolites—the cyanotoxins, Journal of Applied Bacteriology, 72,445–459.
  • 5- Carmicheal, W.W., 1994. The toxins of cyanobacteria, Scientific American, 270, 78–86.
  • 6- Falconer, I.R., Hardy, S.J., Humpage, A.R., Froscio, S M., Tozer, G.J., Hawkins, P.R., 1999. Hepatic and renal toxicity of the blue-green alga (cyanobacterium) Cylindrospermopsis raciborskii in male Swiss Albino mice. J. Environ. Toxicol. Water Qual., (14), 1.
  • 7- Madigan, T.M., Martinko, J. M., Stahl, D. A., Clark, D. P., 2012. Brock biology of microorganisms. Thirteen edition.
  • 8- Chorus, I., and Bartram, J., 1999. Toxic cyanobacteria in water: A guide to their public health consequences, monitoring and management. E & FN Spon, London, WHO, p. 400. Geneva.
  • 9- Mur, L.R., O.M.Skulberg, et al., 1999. Cyanobacteria in the environment. Toxic Cyanobacteria in Water: A Guide to Their Public Health Consequences, Monitoring ans Management. I. Chorus and J.Bartram, eds. London, E and FN Spon (on behalf of WHO):15-40.
  • 10- Whitton, B. A., 2000. Soils and rice-fields. In Whitton, B.A., Potts M. (eds), The Ecology of Cyanobacteria, Kluwer Academic, Dordrecht, pp. 233–255.
  • 11- Duy, T.N., Lam, P.K.S., Shaw, G.R., Connel, D.W., 2000. Toxicology and risk assessment of freshwater cyanobacterial (blue-green algal) toxins in water’. Rev Environ Contam Toxicol, 163, 113-186.
  • 12- Nichols, J.M., Adams, D.J., Carr, N.G., Whitton, B.A., 1982. Akinetes, The Biology Of Cyanobacteria, Blackwell Scientific Publications, Oxford, 378-412.
  • 13- Walsby, A.E., 1987. Mechanisms of buoyancy regulation by planktonic Cyanobacteria with gas vesicles. In: P. Fay and C. Van Baalen (eds) The Cyanobacteria. Elsevier, Amsterdam, 377-414.
  • 14- Güner, H. ve Aysel, V., 2006. Tohumsuz Bitkiler Sistematiği, Cilt 1 (Algler), Ege Üniversitesi Fen Fakültesi Yayınları, Altıncı Baskı, 245s.
  • 15- Chorus, I., 2001. ‘’Cyanotoxins: occurrence, causes, consequence’’, Springer, Heidelberg, Germany.
  • 16- NRA, 1990. Toxic Blue Green Algae. Water Quality Series No.2 National Rivers Authority, pp. 125. London.
  • 17- Carmichael, W.W., Falconer, I.R., 1993. Diseases Related to Freshwater Blue Green Algal Toksins ve Control Measures. In Algal Toksins in Seefood ve Drinking Water Falconer, I.R. (ed) London Academic Press.
  • 18- Codd, G.A., Azevedo, S.M.F.O., Bagchi, S.N., Burch, M.D., Carmichael, W.W., Harding, W.R., Kaya, K. and Utkilen, H.C., 2005. Cyanonet A Global Network for Cyanobacterial Bloom and Toxin Risk Management. The International Hydrological Programme (IHP) of the United Nations Educational, Scientific and Cultural Organization (UNESCO), p. 141. France.
  • 19- Negri, A.P., Jones, G.J., Hindmarsh, M., 1995. Sheep mortality associated with paralytic shellfish poisons from the cyanobacterium Anabaena circinalis, Toxicon, 33:1321-1329.
  • 20- Falconer, I.R., 2001. Toxic Cyanobacteria Bloom Problems in Australian Water: Risks and impacts on Human Health, Phycologia, 40, 228-233.
  • 21- Svircˇev, Z., Baltic´ , V., Miladinov-Mikov, M., Sajenkovic´, D., 2011. Cyanobacterial blooms in Serbia epidemiological studies and health risk assessment, In: 16th Academy of Studenica – International Scientific Conference Cyanobacteria and human health. Novi Sad. Abstract Book, p. 34.
  • 22- Eriksson, J.E., Hagerstrand, H., Isomaa, B., 1987. Cell selective cytotoxicity of a peptide toxin from the cyanobacterium Microcystis aeruginosa, Biochim Biophys Acta, 930(2), 304-310.
  • 23- Runnegar, M., Berndt, N.; Kaplowitz, N., 1995a. Mikrosistin uptake and inhibition of protein phosphatases: effects of chemoprotectants and self-inhibition in relation to known hepatic transporters, Toxicol. App. Pharmacol., 134, 264-72.
  • 24- Fujiki, H., Suganuma, M., 1993. Tumor promotion by inhibitors of protein phosphatases 1 and 2A: the okadaic acid class of compounds. Adv. Cancer Res., (61), 143-194.
  • 25- Harada, K-I., 1996. Chemistry and Detection of Mikrosistins, In: Toxic Microcystis, (M.F. Watanabe, K-I. Harada, W.W. Carmichael and H. Fujiki eds) Chemical Rubber Company (CRC) Press, pp. 103-148. Boca Raton, Florida.
  • 26- Metcalf, J.S., Keneth, A.B., Plugmacher, S., Codd, G.A., 2000. Immunocrossreactivity ve Toxicity assesment of Conjugation Products of the Cyanobacterial toxin, Mikrosistin-LR. FEMS Microbiology Letters, (189), 155-158.
  • 27- Hoeger, S.J., Dietrich, D.R., Hitzfeld, B.C., 2002. Effect of Ozonation on the Removal of Cyanobacterial Toxins during Drinking Water Treatment Environ Health Perspect, (110), 1127–1132.
  • 28- Kellmann, R., Neilan, B. A., 2007, Biochemical characterization of paralytic shellfish toxin biosynthesis in vitro. J. Phycol., 43,497–508.
  • 29- Hawkins, P.R., Chverasena, N.R., Jones, G.J., Humpage, A.R., Falconer, I.R., 1997. Isolation ve toxicity of Cylindrospermopsis raciborskii from an ornamental lake. Toxicon, 35, (3), 341-346.
  • 30- Kiss, T., Vehovszky, A., Hiripi, L., Kovacs, A., Voros, L., 2002. Membrane effects of toxins isolated from a cyanobacterium, Cylindrospermopsis raciborskii, on identified molluscan neurones, Comp. Biochem. Physiol. Part C, 131,167–176.
  • 31- Aykulu, G., Obalı, O., 1981. Phytoplankton biomass in the Kurtboğazı Dam Lake. Communications de la Faculté des sciences de l'Université d'Ankara: Botanique, Serie C2, 24:29-45.
  • 32- Obalı, O., 1984. Mogan gölü fitoplanktonunun mevsimsel değişimi. Doğa Bilim Dergisi, 8(1): 91–104.
  • 33- Cirik, S., Cirik, Ş., 1989. Gölcük'ün (Bozdağ/İzmir) Planktonik Algleri. İ.Ü. Su Ürün.Derg., Cilt: 3, Sayı 1-2: 131-150, İstanbul.
  • 34- Aykulu, G., Doğan, K., Hasırcı, S., 1999. Phytoplankton communities of the lakes Taşkısığı and Poyrazlar (Adapazarı, Turkey). İstanbul Üniversitesi Su Ürünleri Dergisi, Özel Sayı, 157 - 184.
  • 35- Albay, M., Akçaalan, R., Aykulu, G., Tüfekçi, H., Beattie, K.A., Codd, G.A., 2003. Occurence of toxic cyanobacteria before and after copper sulphate treatment in a water reservior, İstanbul, Turkey, Algological Studies 109,67-68.
  • 36- Albay, M., Akçaalan, R., Köker, L., Gurevin, C., 2014. Planktothrix rubescens: A perennial presence and toxicity in Lake Sapanca. Turkish Journal of Botany, 38:782-789.
  • 37- Albay, M., Matthiensen, A., Cood, G., 2005. Occurrence of toxic blue-green algae in the Kucukcekmece Lagoon (Istanbul, Turkey). Environmental Toxicology 20(3):277-84.
  • 38- Demir, N., 2007. Changes in the phytoplankton community of a coastal, hyposaline lake in western Anatolia, Turkey. Limnology, 8:337–342.
  • 39- Kızılkaya, I,T., Demirel, Z., Kesici, K., Kesici, E., Sukatar, A., 2016. Morphological, Molecular and Toxicologial Characterization of Nodularia spumigena Mertens in Jungens (1822) from Brackishwater Lake Bafa (Turkey). Sinop Uni. J. Nat. Sci. 1(1): 39-52.
  • 40- Akçaalan, R., Köker, L., Oğuz, A., Albay, M., 2014. First Report of Cylindrospermopsin Production by Two Cyanobacteria (Dolichospermum mendotae and Chrysosporum ovalisporum) in Lake Iznik, Turkey. Toxins 6(11):3173-3186.
  • 41- Albay, M., Akçaalan, R., Köker, L., 2016. Do Eutrophic Waters Prompt to Toxic Cyanobacteria in Turkish Black Sea Coast?. Journal of environmental protection and ecology 17(2):584-592.
  • 42- Köker, L., Akçaalan, R., Albay, M., Neilan, B., 2017. Molecular detection of hepatotoxic cyanobacteria in inland water bodies of the Marmara Region, Turkey. Advances in Oceanography and Limnology,8(1).
  • 43- Yılmaz, M., Foss, A,J., Miles, C,O., Özen, M., Balcı, M., Demir, N., Beach, D.G. Hing, 2018. Diversity of Microcystins in a Microcystis aeruginosa Isolate from Lake Uluabat. 13th International Symposium on Fisheries and Aquatic Sciences Proceding Book ISBN: 978-605-68894-0-0 Publication of e-book date: 17.12.2018.
  • 44- Koker, L., Akçaalan, A., Oguz, A., Gaygusuz, O., Gurevin, C., Akat Kose, C., Gucver, S., Karaaslan,Y., Erturk, A., Albay, M., Kınacı, C., 2017. Distribution of Toxic Cyanobacteria and Cyanotoxins in Turkish Waterbodies. Journal of Environmental Protection and Ecology 18, 425-432.
  • 45- Tisdale, E.S., 1931. Epidemic of intestinal disorders in Charleston, W. VA., Occurring simultaneously with unprecedented water supply conditions. American Journal of Public Health, (21), 198-200.
  • 46- Zilberg, B., 1966. Gastroenteritis in Salisbury European children-a five-year study. The Central African Journal of Medicine, (12), 164-168.
  • 47- Botes, D.P., Tuinman, A.A., Wessels, P.L., Viljoen, C.C., Kruger, H., Williams, D.H. Santikarn, S., 1984. The Structure of Cyanoginosin-LA, A Cyclic Heptapeptide Toxin From The Cyanobacterium Microcystis Aeruginosa. J. Chem. Soc., Perkin Transactions, (1), 2311-2318.
  • 48- Teixera, M.G.L.C., Costa, M.C.N., Carvalho, V.L.P., Pereira, M.S., Hage, E., 1993. Gastroenteritis epidemic in the area of the Itaparica Dam, Bahia, Brazil. Bulletin of the Pan American Health Organization, (27), 244-253.
  • 49- Byth, S., 1980. Palm Island mystery disease, Med. J. Aust., 2,40-42.
  • 50- Pouria, S.A., Barbosa, J., Cavalcanti, R.L., Barreto, V.T.S., Ward, C.J., Preiser, W., Poon, G.K., Neild, G.H., Codd, G.A., 1998. Fatal Mikrosistin intoxication in haemodialysis unit in Caruaru, Brazil. The Lancet, 352: 21-25.
There are 50 citations in total.

Details

Primary Language Turkish
Subjects Hydrobiology
Journal Section Makaleler
Authors

Hacer Merve Koca 0000-0002-2538-9388

Ayşe Nilsun Demir 0000-0002-3895-7655

Mehmet Tahir Alp 0000-0003-2639-4549

Publication Date September 26, 2019
Submission Date May 9, 2019
Acceptance Date July 8, 2019
Published in Issue Year 2019 Issue: 367

Cite

APA Koca, H. M., Demir, A. N., & Alp, M. T. (2019). İÇSULARDA SİYANOBAKTERİ ARTIŞLARI VE OLUŞTURDUĞU RİSKLER. Ziraat Mühendisliği(367), 25-35. https://doi.org/10.33724/zm.562579