Year 2017, Volume 2, Issue 3, Pages 211 - 222 2017-12-31

GİNSENGİN ÖZELLİKLERİ ve SAĞLIK ÜZERİNE ETKİLERİ

Aysun Taşdemir [1] , Ayşe Merve Yaman [2]

384 2934

Ginseng uzak doğu ülkelerinde tıpta kullanılan bir bitkidir. Tüm şifalı bitkiler arasında strese karşı en etkili direnç arttırıcı bitki olduğu düşünülmektedir. Dünya çapında en çok satılan doğal ürünler listesinde yerini almıştır. Bu yüzden tüketimi gittikçe artmaktadır. Günümüzde tabletleri de yapılan ginseng özlü gıda takviyeleri Kore ya da Asya Ginsengi, Sibirya Ginsengi ve Amerikan Ginsengi gibi pek çok tanınmış bitki türlerinin köklerinden yapılmaktadır. Ginseng'in, stres ve yaşlanmaya karşı direnci arttıran dolayısıyla yaşam kalitesini arttıran bir tonik veya adaptojenik madde olduğu gösterilmiştir. Ginseng'in genel olarak insanlardaki fiziksel ve zihinsel kapasiteyi arttırdığı, yorgunluğu azalttığı ve fiziksel dayanıklılığı arttırdığı bilinmektedir. Ginsengin içinde bulunan ginsenozidlerin, ginsengin oluşturduğu etkilerin çoğuna sebep olduğu düşünülmektedir.

Ginseng; Ginsenozid
  • Attele, A., & Yuan, C. (1999). Ginseng pharmacology: multiple constituents and multiple actions. Biochemical Pharmacology, 58(11), 1685-1693.
  • Bahrke, M., & Morgan, W. (1994). Evaluation of the ergogenic properties of ginseng. Sports Medicine, 18(4), 229-248.
  • Bahrke, M., & Morgan, W. (2000). Evaluation of the ergogenic properties of ginseng: an update. Sports Medicine, 29(2), 113-133.
  • Baytop, T. (1999). Türkiye'de Bitkiler İle Tedavi Geçmişte ve Bugün. İstanbul: Nobel Tıp Kitabevi.
  • Block, K., & Mead, M. (2003). Immune system effects of echinacea, ginseng and astragalus: a review. İntegrative Canser Therapies, 2(3), 247-267.
  • Bruce, A., Ekblom, B., & Nilsson, I. (1985). The effect of vitamin and mineral supplements and health foods on physical endurance and performance. Proceedings of the Nutrition Society, 44(2), 283-295.
  • Byun, B., Shin, I., Yoon, Y., Kim, S., & Joe, C. (1997). Modulation of protein kinase C activity in NIH 3T3 cells byplant glycosides from Panax ginseng. Planta Medica, 63(5), 389-392.
  • Court, W. (1975). Ginseng a chinese folk medicine of current interest. The Pharmaceutical Journal, 214, 180-181.
  • Demirezer, Ö. (2011). FFD Monologları Tedavide Kullanılan Bitkiler. Ankara: Akademisyen Kitabevi.
  • Dowling, E., Redondo, D., Branch, J., Jones, S., Mcnabb, G., & Williams, M. (1996). Effect of eleutherococcus senticosus on submaximal and exercise performance. Medicine and Science in Sports and Exercise Journal, 28(4), 482-489.
  • Ernst, E. (2002). The risk-benefit profile of commonly used herbal therapies: Ginkgo, St. John's Wort, Ginseng, Echinacea, Saw Palmetto and Kava. Annals of İnternal Medicine, 136(1), 42-53.
  • Fulder, S. (1981). Ginseng and the hypothalamic-pituitary control of stress. The Americal Journal of Chinese Medicine, 9(2), 112-118.
  • Goldstein , B. (1975). Ginseng its history, dispersion and folk tradition. The American Journal of Chinese Medicine, 3(3), 223-234.
  • Himi, T., Saito, H., & Nishiyama, N. (1989). Effects of ginseng saponins on the survival of cerebral cortex neurons in cell cultures. Chemical and Pharmaceutical Bulletin, 37(2), 481-484.
  • Huang, Q., Wang, T., Yang, L., & Wang, H. (2017). Ginsenoside Rb2 Alleviates Hepatic Lipid Accumulation by Restoring Autophagy Via İnduction of Sirt1 and Activation of AMPK. İnternational Journal of Moleculer Sciences, 18(5), 1063-1078.
  • Jenkins, R., & Goldfarb, A. (1993). İntroduction oxidant stress aging and exercise. Medicine and Science in Sports and Exercise, 25(2), 210-212.
  • Johnny, L., Joseph, W. K., & LuGuang, L. (2016). Effets of ginseng and its four purufied ginsenosides (Rb2,Re,Rg) on human pancreatic islet beta cell invitro. European Journal of Pharmaceutical and Medical Research, 3(1), 110-119.
  • Kennedy, D. O., Scholey, A. B., & Wesnes, K. A. (2002). Modulation of cognition and mood following administration of single doses of Ginkgo Biloba, ginseng and a ginkgo/ginseng combunation to healthy young adults. Physiology and Behavior Journal, 75(5), 739-751.
  • Kiefer, D., & Pantuso, T. (2003). Panax ginseng. American Academy of Family Physicans, 68(8), 1539-1542.
  • Kim, S. J., & Ak, K. (2015). Anti-breast canser activity of fine black ginseng (Panax ginseng meyer) and ginsenoside Rg5. Journal of Ginseng Research, 39(2), 125-134. Liberti, L. E., & Der, M. A. (1978). Evaluation of commercial ginseng products. Journal of Pharmaceutical Sciences, 67(10), 1487-1489.
  • Liu, C., & Xiao, P. (1992). Recent advances on ginseng research in Chine. Journal of Ethnopharmacology, 36(1), 27-38.
  • Ma, G. D., Chiu, C. H., Hsu, Y. J., Hou, C. W., Chen, Y. M., & Huang, C. C. (2017). Changbai mountain ginseng (Panax ginseng C.A. Mey) extract supplementation improves exercise performance and energy utilizationand decreases fatigue-associated parameters. Molecules, 22(2), 237-250.
  • Mahady, G. B., Gyllenhall, C., Fong, H. H., & Farnsworth, N. R. (2000). Ginsengs, a review of safety efficacy. Nutrition in Clinical Care, 3(2), 90-101.
  • McNaughton, L., Egan, G., & Caelli, G. A. (1988). Comparison of Chinese and Russian ginseng as ergogenic aids to improve various facets of physical fitness. İnternational Journal of Clinical Nutrition, 19(1), 32-35.
  • Murphy, L. L., & Lee, T. J. F. (2002). Ginseng, sex behavior, and nitric oxide. Annals of the New York Academy of Sciences, 962(1), 372-377.
  • Nocerino, E., Amato, M., & Izzo, A. A. (2000). The aphrodisiac and adaptogenic properties of ginseng. Fitoterapia, 71(1), 1-5.
  • O'Hara, M., Kiefer, D., Farrell, K., & Kemper, K. (1998). A review of 12 commonly used medicinal herbs. Archives of Family Medicine, 7(6), 523.
  • Paik, D. J., & Lee, C. H. (2015). Review of cases of patient risk associated with ginseng abuse and misuse. Journal of ginseng research, 39(2), 89-93.
  • Phillipson, J. D., & Anderson, L. A. (1984). Ginseng-quality safety and efficacy. The Pharmaceutical Journal, 232, 161-165.
  • (Scaglione, F., Cattaneo, G., Alessandria, M., & Cogo, R. (1996). Efficacy and safety of the standardised Ginseng extract G115 for potentiating vaccination against common cold and/or influenza syndrome. Drugs Under Experımental and Clinical Research, 22(6), 338-338.
  • Scaglione, F., Ferrara, F., Dugnani, S., Falchi, M., Santoro, G., & Fraschini, F. (1990). Immunomodulatoryeffects of two extracts of panax ginseng C.A. Meyer. Drugs under experimental and clinical research, 16(10), 537-542.
  • Scaglione, F., Weiser, K., & Alessandria, M. (2001). Effects of the standardised ginseng extract G115® in patients with chronic bronchitis. Clinical Drug İnvestigation, 21(1), 41-45.
  • Sezik, E., Yeşilada, E., & Demirezer, Ö. (2004). Hızlandırılmış Fitoterapi Meslek İçi Eğitim Programı Ders Notları, Ankara: Türk Eczacılar Birliği Eczacılık Akademisi.
  • Shin, H. Y., Jeong, H. J., An, H. J., Hong, S. H., Um, J. Y., Shin, T. Y., Kuson, S. J., Jee, S. Y., Seo, B.II, Shin, S. S.,Yang, D.C., & Kim, H. M. (2006). The effect of panax ginseng on fonced immobility time ve immunefunction in mice, Indian Journal of Medical Research, 124(2), 199-206.
  • Shishtar, E., Sievenpiper, J. L., Djedovic, V., Cozma, A. I., Ha, V., Jayalath, V. H., Jenkins, D. J., Meija, S. B., De Souza, R. J., Jovanovski, E., & Vuksan, V. (2014). The effect of ginseng (the genus panax) on glycemic control: a systematic review and meta-analysis of randomized controlled clinical trials. Plos One, 9 (9), 1-11.
  • Siegel, R. K. (1979). Ginseng abuse syndrome, problems with the panacea. Jama, 241(15), 1614–1615.
  • Song, X., Wu, H., Yin, Z., Lian, M., & Yin, C. (2017). Endophytic Bacteria Isolated from Panax ginseng Improves Ginsenoside Accumulation in Adventitious Ginseng Root Culture. Molecules, 22(6), 837-849.
  • Tanker, N., Koyuncu, M., & Coşkun, M. (2007). Farmasotik Botanik, Ankara: Ankara Üniversitesi Eczacılık Fakültesi Yayınları.
  • Vonardenne, V. M., & Klemm, W. (1987). Measurements of the Increase in the difference between thearterial and venous Hb-O2 saturation obtained with daily administration of 200 mgstandardized ginseng extract G115 for Four weeks. Panminerva, 29(2), 143–150.
  • Yang, L., Qing, T. Y., Ya-Zhong, G., Wen-Song, Z., Yong, F., Chung-Wah, M., Qun, L., & Lian-Wen, Q. (2016) Distinct urine metabolome after Asian ginseng and American ginseng intervention based on GC-MS metabolomics approach. Scientific Reports, 6 (39045), 1-11.
  • Wang, W., Shen, H., Xie, J. J., Ling, J., & Lu, H. (2015). Neuroprotective effect of ginseng against spinal cord injury induced oxidative stress and inflammatory responses. International Journal of Clinical and Experimental Medicine, 8(3), 514-521.
  • Wen, T. C., Yoshimura, H., Matsuda, S., Lim, J. H., & Sakanaka, M. (1996). Ginseng root prevents learning disability and neuronal loss in gerbils with 5-minute forebrain ischemia. Acta neuropathologica, 91(1), 15-22.
  • World Health Organization. (1999). WHO Monographs on Selected Medicinal Plants. Geneva: World Health Organization.
  • Wilkie, A., & Cordess, C. (1994). Ginseng—a root just like a carrot?. Journal of the Royal Society of Medicine, 87(10), 594-595.
Subjects Social Sciences, Interdisciplinary
Journal Section reviews
Authors

Author: Aysun Taşdemir
Institution: KASTAMONU ÜNİVERSİTESİ
Country: Turkey


Author: Ayşe Merve Yaman
Country: Turkey


APA Taşdemir, A , Yaman, A . (2017). GİNSENGİN ÖZELLİKLERİ ve SAĞLIK ÜZERİNE ETKİLERİ. Sağlık Akademisi Kastamonu, 2 (3), 211-222. DOI: 10.25279/sak.321750