Öz
Sinoviyal sarkomlar artiküler tendonlardan ve eklem kapsüllerinden köken alan nadir malign tümörlerdir. Histolojik olarak sinoviyuma benzerlikleri nedeniyle sinoviyal sarkom olarak isimlendirilmelerine rağmen, nadiren sinoviyal yapı içerirler. Genellikler alt ekstremitede görülmekle birlikte nadir olarak toraks, abdomen, baş-boyun bölgesinde sinoviyal sarkom tespit edilen olgular bildirilmiştir. 60 yaşında erkek hasta boyun sol yarısında şişlik şikayeti ile hastanemize başvurdu. Çekilen bilgisayarlı tomografide sol parafaringeal boşluğu ve sol submandibular fossayı doldurup, farenk lümenine protrude yaklaşık 6,5x5 cm boyutunda kitle tespit edildi. Kitle düzgün sınırlı, ovoid şekilli ve çevre dokulara infiltrasyon göstermemekteydi. Cerrahi olarak total çıkarılan kitlenin histopatolojik tanısı sinovyal sarkom olarak belirlendi. Nadir görülmelerine rağmen sinoviyal sarkomlar Ewing sarkomu, rabdomiyosarkom ve diğer sarkomlarla birlikte kalsifikasyon içeren jukstaartiküler kitlelerin ayırıcı tanısında düşünülmelidir.
Anahtar Kelimeler
sinoviyal sarkom bilgisayarlı tomografi jugulodigastric boşluk boyun
Kaynakça
- Brennan MF, Antonescu CR, Moraco N, Singer S. Lessons learned from the study of 10,000 patients with soft tissue sarcoma. Annals of surgery. 2014;260(3):416-21.
- Brennan MF, Singer S, Maki RG. Sarcomas of the soft tissues and bone. In: Devita V, Hellman S, Rosenberg SJNYL. Cancer: principles and practice of oncology, 7th. 2005:1584.
- Kransdorf MJ. Malignant soft-tissue tumors in a large referral population: distribution of diagnoses by age, sex, and location. AJR American journal of roentgenology. 1995;164(1):129-34. (doi:10.2214/ajr.164.1.7998525).
- Koga C, Harada H, Kusukawa J, Kameyama TJOOE. Synovial sarcoma arising in the mandibular bone. 2005;41(3):45-8. (doi: 10.1016/j.ooe.2004.11.001).
- Jung JI, Kim HH, Park SH, Lee YS. Malignant ectopic thymoma in the neck: a case report. AJNR American journal of neuroradiology. 1999;20(9):1747-9.
- Kakimoto N, Gamoh S, Tamaki J, Kishino M, Murakami S, Furukawa S. CT and MR images of pleomorphic adenoma in major and minor salivary glands. European journal of radiology. 2009;69(3):464-72. (doi: 10.1016/j.ejrad.2007.11.021).
- Yao H, Lin H, Zhang P, Zhang T, Feng LJTC-GJoCO. CT and MRI findings of parotid Warthin’s tumors. 2011;10(10):596. (doi: 10.1007/s10330-011-0845-0).
- Gökaslan ÇO, Toprak U. Parafaringeal Bölge Radyolojisi. Turkiye Klinikleri Ear Nose and Throat-Special Topics. 2017;10(2):120-7.
- Som PM, Brandweine-Gensler MS. Lymph nodes of the neck. In: Som PM, Curtin HD. Head and Neck Imaging E-Book: Elsevier Health Sciences 5th; 2011:2287-378.
- Eilber FC, Dry SM. Diagnosis and management of synovial sarcoma. J Surg Oncol 2008;97:314-20. (doi: 10.1002/jso.20974).
- Murphey MD, Gibson MS, Jennings BT, Crespo-Rodríguez AM, Fanburg-Smith J, Gajewski DAJR. Imaging of synovial sarcoma with radiologic-pathologic correlation. 2006;26(5):1543-65. (doi: 10.1148/rg.265065084).
- Kransdorf MJ, Murphey MD. Imaging of soft tissue tumors. 2nd ed. Philadelphia: Lippincott William & Wilkins 2006.
- Nakanishi H, Araki N, Sawai Y, Kudawara I, Mano M, Ishiguro S, et al. Cystic synovial sarcomas: imaging features with clinical and histopathologic correlation. 2003;32(12):701-7. (doi: 10.1007/s00256-003-0690-5).
- Bakri A, Shinagare AB, Krajewski KM, Howard SA, Jagannathan JP, Hornick JL, et al. Synovial sarcoma: imaging features of common and uncommon primary sites, metastatic patterns, and treatment response. 2012;199(2):W208-W15. (doi: 10.2214/AJR.11.8039).
Öz
Synovial sarcomas are rare malignant neoplasms commonly arising from articular tendons and joint capsules. Despite being termed synovial sarcomas due to their histologic similarity to the synovium, they rarely involve a synovial structure. Although they mostly occur in lower extremities, rare cases originating from the thorax, abdomen, head, and neck have also been reported. A 60-year-old male patient was admitted to the hospital with a complaint of swelling in left side of the neck. CT revealed a mass of approximately 6.5x5 cm, occupying the left parapharyngeal space and left submandibular fossa and protruding into the pharynx lumen. The lesion was non-infiltrative, well circumscribed, and uniformly ovoid. The patient underwent surgery, and subsequent pathological examination confirmed the diagnosis of synovial sarcoma. Despite their rarity, synovial sarcomas should be considered, along with Ewing’s sarcoma, rhabdomyosarcoma, and other sarcomas, in the differential diagnosis of a large juxtaarticular mass containing calcifications.
Anahtar Kelimeler
synovial sarcoma computed tomography jugulodigastric space neck
Kaynakça
- Brennan MF, Antonescu CR, Moraco N, Singer S. Lessons learned from the study of 10,000 patients with soft tissue sarcoma. Annals of surgery. 2014;260(3):416-21.
- Brennan MF, Singer S, Maki RG. Sarcomas of the soft tissues and bone. In: Devita V, Hellman S, Rosenberg SJNYL. Cancer: principles and practice of oncology, 7th. 2005:1584.
- Kransdorf MJ. Malignant soft-tissue tumors in a large referral population: distribution of diagnoses by age, sex, and location. AJR American journal of roentgenology. 1995;164(1):129-34. (doi:10.2214/ajr.164.1.7998525).
- Koga C, Harada H, Kusukawa J, Kameyama TJOOE. Synovial sarcoma arising in the mandibular bone. 2005;41(3):45-8. (doi: 10.1016/j.ooe.2004.11.001).
- Jung JI, Kim HH, Park SH, Lee YS. Malignant ectopic thymoma in the neck: a case report. AJNR American journal of neuroradiology. 1999;20(9):1747-9.
- Kakimoto N, Gamoh S, Tamaki J, Kishino M, Murakami S, Furukawa S. CT and MR images of pleomorphic adenoma in major and minor salivary glands. European journal of radiology. 2009;69(3):464-72. (doi: 10.1016/j.ejrad.2007.11.021).
- Yao H, Lin H, Zhang P, Zhang T, Feng LJTC-GJoCO. CT and MRI findings of parotid Warthin’s tumors. 2011;10(10):596. (doi: 10.1007/s10330-011-0845-0).
- Gökaslan ÇO, Toprak U. Parafaringeal Bölge Radyolojisi. Turkiye Klinikleri Ear Nose and Throat-Special Topics. 2017;10(2):120-7.
- Som PM, Brandweine-Gensler MS. Lymph nodes of the neck. In: Som PM, Curtin HD. Head and Neck Imaging E-Book: Elsevier Health Sciences 5th; 2011:2287-378.
- Eilber FC, Dry SM. Diagnosis and management of synovial sarcoma. J Surg Oncol 2008;97:314-20. (doi: 10.1002/jso.20974).
- Murphey MD, Gibson MS, Jennings BT, Crespo-Rodríguez AM, Fanburg-Smith J, Gajewski DAJR. Imaging of synovial sarcoma with radiologic-pathologic correlation. 2006;26(5):1543-65. (doi: 10.1148/rg.265065084).
- Kransdorf MJ, Murphey MD. Imaging of soft tissue tumors. 2nd ed. Philadelphia: Lippincott William & Wilkins 2006.
- Nakanishi H, Araki N, Sawai Y, Kudawara I, Mano M, Ishiguro S, et al. Cystic synovial sarcomas: imaging features with clinical and histopathologic correlation. 2003;32(12):701-7. (doi: 10.1007/s00256-003-0690-5).
- Bakri A, Shinagare AB, Krajewski KM, Howard SA, Jagannathan JP, Hornick JL, et al. Synovial sarcoma: imaging features of common and uncommon primary sites, metastatic patterns, and treatment response. 2012;199(2):W208-W15. (doi: 10.2214/AJR.11.8039).
Ayrıntılar
| Birincil Dil | İngilizce |
|---|---|
| Konular | Sağlık Kurumları Yönetimi |
| Bölüm | Vaka sunumu |
| Yazarlar | |
| Yayımlanma Tarihi | 1 Mart 2020 |
| Yayımlandığı Sayı | Yıl 2020 Cilt: 12 Sayı: 1 |
e-ISSN: 2548-0251
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