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The use of empirical antibiotics in intensive care unit and relationship between nutrition and the incidence of infection

Yıl 2019, Cilt: 46 Sayı: 3, 489 - 498, 16.09.2019

Salih Yıldırım Yavuz Orak Rukiye Menemencioğlu Ahmet Altun Filiz Orak Cevdet Düger Esra Özpay Fatih Mehmet Yazar

https://doi.org/10.5798/dicletip.620514

Öz

Objective: Aim of study is to determine which antibiotic is started empirically in the ICU and to investigate whether the antibiotic started according to culture result was changed or not and the effect of this change on mortality, and to investigate the relationship between mortality and infection by determining whether enteral and parenterally fed patients have attained sufficient calorie level.
Method: After the approval of the local ethics committee, the files of 476 patients hospitalized in our hospital were retrospectively reviewed. A total of 159 patients over 18 years of age who received mechanical ventilation therapy for at least 3 days were included in the study. Blood, urine and tracheal aspirate culture were determined. It was recorded whether antibiotics had changed according to the culture result. Nutritional patterns, number of feeding days and basal caloric need were determined. It was investigated whether basal calorie need was met on 1, 3 and 5 days. Factors affecting mortality were investigated.
Results: Antibiotic exchange was significantly higher in the patients who died (P = 0.002). Mortality was higher in patients who were unable to reach the target calorie (P = 0.01). Empirical changes in antibiotics (r: 0.174, P = 0.028), and culture positivity (r: 0.177, P = 0.026) were associated with mortality (r: 0.195, P = 0.014). In the subgroup analysis, reproduction in tracheal aspirate culture was an important factor affecting mortality (r: 0.211 P: 0.008).
Conclusions: The number of days of hospitalization, antibiotic change, culture positivity and inability to reach the target calories in nutrition are associated with mortality in the intensive care unit.

Anahtar Kelimeler

empirical antibiotic therapy mortality intensive care unit

Kaynakça

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Toplam 30 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Sağlık Kurumları Yönetimi
Bölüm Original Articles
Yazarlar

Salih Yıldırım Bu kişi benim 0000-0002-4986-6812

Yavuz Orak Bu kişi benim 0000-0002-8356-6223

Rukiye Menemencioğlu Bu kişi benim 0000-0002-7053-8143

Ahmet Altun Bu kişi benim 0000-0003-2056-8683

Filiz Orak Bu kişi benim 0000-0001-5153-7391

Cevdet Düger Bu kişi benim 0000-0002-3845-8733

Esra Özpay Bu kişi benim 0000-0003-0187-9910

Fatih Mehmet Yazar Bu kişi benim 0000-0002-1780-6962

Yayımlanma Tarihi 16 Eylül 2019
Gönderilme Tarihi 11 Nisan 2019
Yayımlandığı Sayı Yıl 2019 Cilt: 46 Sayı: 3

Kaynak Göster

APA Yıldırım, S., Orak, Y., Menemencioğlu, R., Altun, A., vd. (2019). The use of empirical antibiotics in intensive care unit and relationship between nutrition and the incidence of infection. Dicle Tıp Dergisi, 46(3), 489-498. https://doi.org/10.5798/dicletip.620514
AMA Yıldırım S, Orak Y, Menemencioğlu R, Altun A, Orak F, Düger C, Özpay E, Yazar FM. The use of empirical antibiotics in intensive care unit and relationship between nutrition and the incidence of infection. diclemedj. Eylül 2019;46(3):489-498. doi:10.5798/dicletip.620514
Chicago Yıldırım, Salih, Yavuz Orak, Rukiye Menemencioğlu, Ahmet Altun, Filiz Orak, Cevdet Düger, Esra Özpay, ve Fatih Mehmet Yazar. “The Use of Empirical Antibiotics in Intensive Care Unit and Relationship Between Nutrition and the Incidence of Infection”. Dicle Tıp Dergisi 46, sy. 3 (Eylül 2019): 489-98. https://doi.org/10.5798/dicletip.620514.
EndNote Yıldırım S, Orak Y, Menemencioğlu R, Altun A, Orak F, Düger C, Özpay E, Yazar FM (01 Eylül 2019) The use of empirical antibiotics in intensive care unit and relationship between nutrition and the incidence of infection. Dicle Tıp Dergisi 46 3 489–498.
IEEE S. Yıldırım, Y. Orak, R. Menemencioğlu, A. Altun, F. Orak, C. Düger, E. Özpay, ve F. M. Yazar, “The use of empirical antibiotics in intensive care unit and relationship between nutrition and the incidence of infection”, diclemedj, c. 46, sy. 3, ss. 489–498, 2019, doi: 10.5798/dicletip.620514.
ISNAD Yıldırım, Salih vd. “The Use of Empirical Antibiotics in Intensive Care Unit and Relationship Between Nutrition and the Incidence of Infection”. Dicle Tıp Dergisi 46/3 (Eylül 2019), 489-498. https://doi.org/10.5798/dicletip.620514.
JAMA Yıldırım S, Orak Y, Menemencioğlu R, Altun A, Orak F, Düger C, Özpay E, Yazar FM. The use of empirical antibiotics in intensive care unit and relationship between nutrition and the incidence of infection. diclemedj. 2019;46:489–498.
MLA Yıldırım, Salih vd. “The Use of Empirical Antibiotics in Intensive Care Unit and Relationship Between Nutrition and the Incidence of Infection”. Dicle Tıp Dergisi, c. 46, sy. 3, 2019, ss. 489-98, doi:10.5798/dicletip.620514.
Vancouver Yıldırım S, Orak Y, Menemencioğlu R, Altun A, Orak F, Düger C, Özpay E, Yazar FM. The use of empirical antibiotics in intensive care unit and relationship between nutrition and the incidence of infection. diclemedj. 2019;46(3):489-98.