Malignensi, Hiperparatiroidizm, Hipokalsiüri ve Yüksek Doz Vitamin D Kullanım Öyküsü Olan Hiperkalsemik Bir Hasta;Yaklaşım ve Kısa Literatür İncelemesi

Abstract

Hiperkalsemi, sık görülen bir medikal problem olup pek çok sebebi vardır. En sık rastlanılan sebepleri malign hastalıklar ve primer hiperparatiroidizmdir. Ek olarak granülomatöz hastalıklar, ilaçlara bağlı hiperkalsemi ve çeşitli endokrin hastalıklar da hiperkalsemiye sebep olabilir. Hiperkalseminin klinik prezantasyonu ve prognozu; hiperkalsemi gelişme hızı, hiperkalseminin şiddeti ve altta yatan sebeplere bağlıdır. Birçok hasta konstitüsyonel, nörolojik, gastrointestinal semptomlar ve renal hastalık semptom ve bulguları ile başvurabilirler. Ciddi hiperkalsemide, hızlı ve etkili bir tedavi hayat kurtarıcıdır. Raporumuzda, merkezimize hiperkalsemi ile başvurup; malignite, hiperparatiroidizm, hipokalsiüri, tiazid diüretiği ve aktif-inaktif D vitamini kullanımı gibi bir çok hiperkalsemi sebebi olan bir hastaya yaklaşımımızı ve literatür bilgisini sunmayı amaçladık.

Keywords

• Anahtar hiperparatiroidi
• hipokalsiüri
• vitamin D

A Hypercalcemic Patient With Malignancy, Hyperparathyroidism, Hypercalciuria and Vitamin D Overdose; Management and Brief Literature Review

Abstract

Hypercalcemia is a common medical problem which has many causes. The most common causes of hypercalcemia are malignant diseases and primary hyperparathyroidism. Additionally granulomatous diseases, medications, endocrinological diseases may cause hypercalcemia. The clinical presentation and prognosis of hypercalcemia is related to the speed of development of hypercalcemia, underlying diseases and the severity of hypercalcemia. Most patients apply with constitutional, gastrointestinal and neurological symptoms or signs and symptoms of renal disorders. In patients with severe hypercalcemia, fast and effective therapy is essential. In this report, we aimed to discuss literature and management of a patient with hypercalcemia who has numerous etiologic factors for hypercalcemia as malign disease, hyperparathyroidism, hypocalciuria, usage of thiazide diuretic and active-inactive vitamin D.

Keywords

• Hypercalcemia
• neoplasm
• hyperparathyroidi
• hypocalciuria
• vitamin D

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