Frequency of troponin elevations in patients with COVID-19 and clinical course in these patients

Abstract

Aim: We aimed to determine the frequency of troponin elevations in COVID-19 patients and to investigate the role of troponin in demonstrating the prognosis of COVID-19 by examining the clinical course of theese patients. Material and Method: Patients diagnosed with COVID-19 disease were included in the study. Patient files were analyzed retrospectively through the hospital information management system.Patients with high troponin levels were identified and comparisons were made with patients with normal troponin levels. Results: 1468 patients were included in the study.Troponin level was found to be high in 6.7% of the patients.The presence of pneumonia on thorax CT rate,hospitalization rate,ICU admission rate,intubation rate was significantly higher in patients with high troponin levels.The mortality rate was 2.1% in the whole group.The mortality rate was significantly higher in the patients with high troponin levels.Total length of hospital and ICU stay were significantly higher in patients with high troponin levels.There was a significant positive correlation between the troponin levels of the patients at admission and the total length of hospital stay and length of ICU stay. 49.5% of COVID-19 patients had another comorbid disease.Hypertension was the most common comorbid disease. The rate of troponin elevation and troponin levels were significantly higher in patients with other comorbid diseases. Conclusion: It has been found that high troponin levels in COVID-19 patients may be associated with a poor clinical prognosis. Troponin can be used as a predictor of prognosis with more comprehensive studies and long-term follw-up results in the future.

Keywords

• COVID-19
• SARS .CoV-2
• troponin
• cardiac biomarkers
• prognosis

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