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The Relationship Between Vaginal Microbiome and Infertility: A Descriptive Trend Analysis (1947-2024)

Cilt: 6 Sayı: 2 20 Mayıs 2025
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The Relationship Between Vaginal Microbiome and Infertility: A Descriptive Trend Analysis (1947-2024)

Öz

Background: The menstrual cycle and gestational state, as well as other physiological factors, have a substantial impact on the vaginal microbiome, which aids in preventing infections caused by pathogenic microorganisms. Dysbiosis of the vaginal microbiome can cause infertility as well as adverse outcomes in pregnancy. The aim of this study is to examine the studies examining the relationship between vaginal microbiota and infertility in Scopus and WoS databases in terms of different variables and to compare them by revealing their bibliometric profiles. Methods: We conducted a bibliometric study to determine the scholarly papers published across all journals that addressed the relationship between the vaginal microbiome and infertility. Scopus and Web of Science (WoS) databases were accessed for all the published articles on vaginal microbiome and infertility. The number of publications by year, language, country, institute, author, journal, and impact factors (IF) are reported as bibliometric indicators. Results: Our findings indicate that the topic is much understudied; only 161 papers met the criteria set forth in our research. But, a striking increase was observed after 2020. The United States, China and Italy drew attention as the countries that contributed the most to the literature. Conclusion: Prospective and clinical studies on the mechanisms linking the vaginal microbiome of the female reproductive system to reproductive physiology may shed light on infertility treatment.

Anahtar Kelimeler

vaginal microbiome, dysbiosis, infertility, bibliometrci analysis

Destekleyen Kurum

This research received no external funding.

Etik Beyan

The data used in this study are publicly available; contain no protected health information or patient information from the authors' institutions. Neither human nor animal subject data are used in our investigation. Therefore, institutional review board approval was not sought.

Teşekkür

None to mention.

Kaynakça

  1. Ursell LK, Metcalf JL, Parfrey LW, Knight R. Defining the human microbiome. Nutr Rev. 2012;70(Suppl 1):38–44.
  2. Turnbaugh PJ, Ley RE, Hamady M, Fraser-Liggett CM, Knight R, Gordon JI. The Human Microbiome Project. Nature. 2007;449(7164):804–10.
  3. Cho I, Blaser MJ. The human microbiome: at the interface of health and disease. Nat Rev Genet. 2012;13(4):260–70.
  4. Moreno I, Simon C. Deciphering the effect of reproductive tract microbiota on human reproduction. Reprod Med Biol. 2018;18(1):40–50.
  5. Ma B, Forney LJ, Ravel J. Vaginal microbiome: rethinking health and disease. Annu Rev Microbiol. 2012; 66:371–89.
  6. Kroon SJ, Ravel J, Huston WM. Cervicovaginal microbiota, women's health, and reproductive outcomes. Fertil Steril. 2018;110(3):327–36.
  7. Gupta S, Kakkar V, Bhushan I. Crosstalk between Vaginal Microbiome and Female Health: A review. Microb Pathog. 2019; 136:103696.
  8. Romero R, Hassan SS, Gajer P, Tarca AL, Fadrosh DW, Nikita L, et al. The composition and stability of the vaginal microbiota of normal pregnant women is different from that of non-pregnant women. Microbiome. 2014;2(1):4.
  9. Gajer P, Brotman RM, Bai G, Sakamoto J, Schütte UM, Zhong X, et al. Temporal dynamics of the human vaginal microbiota. Sci Transl Med. 2012;4(132):132ra52.
  10. DiGiulio DB, Callahan BJ, McMurdie PJ, Costello EK, Lyell DJ, Robaczewska A, et al. Temporal and spatial variation of the human microbiota during pregnancy. Proc Natl Acad Sci U S A. 2015;112(35):11060–5.

Kaynak Göster

APA
Erinmez, M., & Koçer, İ. (2025). The Relationship Between Vaginal Microbiome and Infertility: A Descriptive Trend Analysis (1947-2024). Archives of Current Medical Research, 6(2), 126-134. https://doi.org/10.47482/acmr.1599705
AMA
1.Erinmez M, Koçer İ. The Relationship Between Vaginal Microbiome and Infertility: A Descriptive Trend Analysis (1947-2024). Arch Curr Med Res. 2025;6(2):126-134. doi:10.47482/acmr.1599705
Chicago
Erinmez, Mehmet, ve İpek Koçer. 2025. “The Relationship Between Vaginal Microbiome and Infertility: A Descriptive Trend Analysis (1947-2024)”. Archives of Current Medical Research 6 (2): 126-34. https://doi.org/10.47482/acmr.1599705.
EndNote
Erinmez M, Koçer İ (01 Mayıs 2025) The Relationship Between Vaginal Microbiome and Infertility: A Descriptive Trend Analysis (1947-2024). Archives of Current Medical Research 6 2 126–134.
IEEE
[1]M. Erinmez ve İ. Koçer, “The Relationship Between Vaginal Microbiome and Infertility: A Descriptive Trend Analysis (1947-2024)”, Arch Curr Med Res, c. 6, sy 2, ss. 126–134, May. 2025, doi: 10.47482/acmr.1599705.
ISNAD
Erinmez, Mehmet - Koçer, İpek. “The Relationship Between Vaginal Microbiome and Infertility: A Descriptive Trend Analysis (1947-2024)”. Archives of Current Medical Research 6/2 (01 Mayıs 2025): 126-134. https://doi.org/10.47482/acmr.1599705.
JAMA
1.Erinmez M, Koçer İ. The Relationship Between Vaginal Microbiome and Infertility: A Descriptive Trend Analysis (1947-2024). Arch Curr Med Res. 2025;6:126–134.
MLA
Erinmez, Mehmet, ve İpek Koçer. “The Relationship Between Vaginal Microbiome and Infertility: A Descriptive Trend Analysis (1947-2024)”. Archives of Current Medical Research, c. 6, sy 2, Mayıs 2025, ss. 126-34, doi:10.47482/acmr.1599705.
Vancouver
1.Mehmet Erinmez, İpek Koçer. The Relationship Between Vaginal Microbiome and Infertility: A Descriptive Trend Analysis (1947-2024). Arch Curr Med Res. 01 Mayıs 2025;6(2):126-34. doi:10.47482/acmr.1599705