Global Trends in Prenatal Mosaicism Research: Insights from a Bibliometric Analysis (1980–2023)
Abstract
Background: The coexistence of at least two cell lines with different genetic structures (chromosomal or single gene mutation) originating from the same zygote in an organism is defined as mosaicism. This study aimed to present a medical perspective by examining scientific articles published on diagnosis of prenatal mosaicism from a perinatal and genetic perspective with statistical methods.
Methods: The source of our study is the Web of Science (WoS) database. The articles indexed between 1980-2023 were included in our research in the database, and the studies of 2024 were not included since the effect factors are not clear yet. While searching the database, the words “Prenatal Mosaicism” were used as keywords
Results: We reached a total of 2124 publications by analyzing the WoS database using the term "prenatal mosaicism". When the citations of the documents written about prenatal mosaicism are evaluated, we found that the highest citation was made in 2022. Co-citation analysis has shown that there are 9932 authors investigating the issue of prenatal mosaicism. Collaboration and citation collaboration was observed between Mackay Memorial Hospital, National Taiwan University and National Yang Ming University. Prenatal screening and Aneuploidy were found the strongest relationship with prenatal mosaicism.
Conclusions: It is observed that the publications related prenatal mosaicism are associated with prenatal diagnosis and screening and this diagnosis has the highest publication, citation and impact power.
Keywords
Kaynakça
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