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Palliative Gastroenterostomy in Malignant Gastric Outlet Obstruction: A Single-Center, Single Surgical Team Experience

Cilt: 6 Sayı: 3 28 Eylül 2025
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Palliative Gastroenterostomy in Malignant Gastric Outlet Obstruction: A Single-Center, Single Surgical Team Experience

Abstract

Background: Malignant gastric outlet obstruction (GOO) is a common complication of stomach, pancreas, and periampullary region tumors, causing serious nutritional disorders and loss of quality of life. This study evaluated the clinical data and factors affecting the survival of patients who underwent palliative gastroenterostomy. Methods: Data from 23 patients who underwent palliative gastroenterostomy due to malignant gastric outlet obstruction in our center between June 2020 and January 2025 were analyzed retrospectively. Demographic characteristics, preoperative clinical data, intraoperative findings, and postoperative outcomes of the patients were evaluated. Patients were divided into two groups according to their survival times as below and above 90 days; factors affecting survival were analyzed by Kaplan-Meier curves and Cox regression analyses. Results: Patients who lived longer than 90 days had higher Karnofsky Performance Score, lower Charlson Comorbidity Index, higher albumin level, and preserved electrolyte balance (p<0.05). In multivariate analysis, only Clavien-Dindo Classification ≥3a level complications (HR: 60.77; p=0.002) and high Gastric Outlet Obstruction Scoring System (GOOSS) score (HR: 0.01; p=0.008) were identified as factors independently affecting survival. Conclusions: Preoperative oral intake capacity and postoperative major complications are the main determinants that directly affect survival. Parameters such as functional status, comorbidity burden, and metabolic balance should also be taken into account in terms of prognosis. Detection of malignancies before GOO occurs and effective management of complications with a multidisciplinary approach may improve patient outcomes.

Keywords

Malignant gastric outlet obstruction , palliative gastroenterostomy , survival , nutrition , complications

Kaynakça

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Kaynak Göster

APA
Güngör, F., Kılavuz, H., Bozkurt, B., Demir, M., Arslan, M. F., & Kurtuluş, İ. (2025). Palliative Gastroenterostomy in Malignant Gastric Outlet Obstruction: A Single-Center, Single Surgical Team Experience. Archives of Current Medical Research, 6(3), 258-265. https://doi.org/10.47482/acmr.1645120