Clinical Features of Patients with Chronic Rhinitis Symptoms in the Absence of Atopy
Öz
Background: Chronic rhinitis occurs in the presence of symptoms of nasal congestion, rhinorrhea, sneezing or nasal/ eye itching. It is important to make a differential diagnosis, because the treatments for the possible diagnoses differ considerably. The aim of our study was to determine the clinical characteristics of patients presenting with chronic rhinitis symptoms and without atopy.
Methods: In this prospective, descriptive and cross-sectional study, demographic and clinical characteristics of patients were analysed. Visual Analogue Scale was used to determine the severity of rhinitis symptoms. These patients were examined for nasal endoscopic examination.
Results: The median age of the 22 patients included in our study was 44.5 years (range: 18-61). The presence of nasal serous discharge on nasal endoscopy examination was significantly higher in the suspected LAR group than in the NAR group. (p=0.04) The presence of female gender, presence of concomitant allergic disease, presence of allergic disease in the family, presence of triggers, rhinorrhea and nasal itching scores according to the visual analogue scale were higher in the suspected LAR group than in the NAR group, but no statistically significant difference was found.
Conclusion: Local allergic rhinitis should be suspected, in cases where serous discharge is observed during nasal endoscopy, symptoms are exacerbated by known triggers, or there is a personal or family history of allergic disease.
Anahtar Kelimeler
local allergic rhinitis, allergy, atopy, Rhinitis
Destekleyen Kurum
This study has received no funding, granting or sponsorship.
Etik Beyan
The study was approved by the Clinical Research Ethic Committee of Ankara Atatürk Sanatoryum Training and Research Hospital (Number: 2012-KAEK-15/2585, Acceptance Date: 26.10.2022)
Teşekkür
None
Kaynakça
- Wallace DV, Dykewicz MS, Bernstein DI, Blessing-Moore J, Cox L, Khan DA et al. The diagnosis and management of rhinitis: an updated practice parameter [published correction appears in J Allergy Clin Immunol. 2008 Dec;122(6):1237]. J Allergy Clin Immunol. 2008;122(2 Suppl):S1-S84.
- Hellings PW, Klimek L, Cingi C, Agache I, Akdis C, Bachert C et al. Non-allergic rhinitis: Position paper of the European Academy of Allergy and Clinical Immunology. Allergy. 2017;72(11):1657-1665.
- Rondón C, Campo P, Togias A, Fokkens WJ, Durham SR, Poweet DG ET al. Local allergic rhinitis: concept, pathophysiology, and management. J Allergy Clin Immunol. 2012;129(6):1460-1467.
- Dykewicz MS, Wallace DV, Amrol DJ, Baroody FM, Bernstein JA, Craig TJ et al. Rhinitis 2020: A practice parameter update. J Allergy Clin Immunol. 2020;146(4):721-767.
- Rondón C, Romero JJ, López S, Antúnez C, Martín-Casañez E, Torres MJ et al. Local IgE production and positive nasal provocation test in patients with persistent nonallergic rhinitis. J Allergy Clin Immunol. 2007;119(4):899-905.
- Rondón C, Doña I, López S, Campo P, Romero JJ, Torres MJ et al. Seasonal idiopathic rhinitis with local inflammatory response and specific IgE in absence of systemic response. Allergy. 2008;63(10):1352-1358.
- Gómez E, Campo P, Rondón C, Barrionuevo E, Blanca-López, Torres MJ et al. Role of the basophil activation test in the diagnosis of local allergic rhinitis. J Allergy Clin Immunol. 2013;132(4):975-6.e65.
- Rondón C, Campo P, Galindo L, Blanca-López N, Cassinello MS, Rodriguez-Bada JL et al. Prevalence and clinical relevance of local allergic rhinitis. Allergy. 2012;67(10):1282-1288.
- Meltzer EO, Blaiss MS, Naclerio RM, Stoloff SW, Derebery MJ, Nelsonet HS et al. Burden of allergic rhinitis: allergies in America, Latin America, and Asia-Pacific adult surveys. Allergy Asthma Proc. 2012;33 Suppl 1:S113-S141.
- Jáuregui I, Mullol J, Dávila I, Ferrer M, Bartra J, Cuvilloet AD et al. Allergic rhinitis and school performance. J Investig Allergol Clin Immunol. 2009;19 Suppl 1:32-39