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Heavy hemolysis after organophosphate poisoning by chlorpyrifos ethyl

Yıl 2022, Cilt 3, Sayı 3, 247 - 249, 30.09.2022

Öz

Organophosphates (OPs) inactivate the acetylcholinesterase enzyme, thus increasing the cholinergic effect. In a clinical setting, patients with OP poisoning may experience nausea and vomiting, diarrhea, and abdominal pain, or in severe cases respiratory failure, seizures, and death. Rarely, acute hemolysis has also been observed. The existing literature contains few descriptions of several delayed diseases associated with OP poisoning. This article presents the case of a patient who experienced severe hemolysis approximately one week after OP exposure. Only a small number of similar cases have been previously examined.

Kaynakça

  • 1. Yılmaz M, Sebe A, Ay MO, Gürger M. Organophosphate Poisoning and Intermediate Syndrome. AKTD. 2016; 25(1): 70-83.
  • 2. Kadeli D and S.Y. Hanjagi. Hemolysis Caused by Chlorpyriphos Consumption. JCR 2014;4(1):203-5.
  • 3. Eaton DL, Daroff RB, Autrup H, Bridges J, Buffler P, Costa LG, et al. Review of the toxicology of chlorpyrifos with an emphasis on human exposure and neurodevelopment. Crit Rev Toxicol. 2008;38 Suppl 2:1-125.
  • 4. Bagchi D, Bagchi M, Hassoun EA, Stohs SJ. In vitro and in vivo generation of reactive oxygen species, DNA damage and lactate dehydrogenase leakage by selected pesticides. Toxicology 1995; 104: 129-40.
  • 5. Timchalk C, Busby A, Campbell JA, Needham LL, Barr DN. Comparative pharmacokinetics of the organophosphorus insecticide chlorpyrifos and its major metabolites diethylphosphate, diethylthiophosphate and 3,5,6-trichloro-2-pyridinol in the rat. Toxicology 2007; 237: 145-57.
  • 6. Ladell WS. Physiological and clinical effects of organophosphorus compounds. Proc R Soc Med 1961;54:405-6.
  • 7. Ngamdu YB, Sandabe MB, Kodiya AM, Isa A, Garandawa HI. Sudden Anosmia due to Otapiapia (Organophosphate Pesticide) Exposure. JCR. 2012;2(2):8-9.

Yıl 2022, Cilt 3, Sayı 3, 247 - 249, 30.09.2022

Öz

Kaynakça

  • 1. Yılmaz M, Sebe A, Ay MO, Gürger M. Organophosphate Poisoning and Intermediate Syndrome. AKTD. 2016; 25(1): 70-83.
  • 2. Kadeli D and S.Y. Hanjagi. Hemolysis Caused by Chlorpyriphos Consumption. JCR 2014;4(1):203-5.
  • 3. Eaton DL, Daroff RB, Autrup H, Bridges J, Buffler P, Costa LG, et al. Review of the toxicology of chlorpyrifos with an emphasis on human exposure and neurodevelopment. Crit Rev Toxicol. 2008;38 Suppl 2:1-125.
  • 4. Bagchi D, Bagchi M, Hassoun EA, Stohs SJ. In vitro and in vivo generation of reactive oxygen species, DNA damage and lactate dehydrogenase leakage by selected pesticides. Toxicology 1995; 104: 129-40.
  • 5. Timchalk C, Busby A, Campbell JA, Needham LL, Barr DN. Comparative pharmacokinetics of the organophosphorus insecticide chlorpyrifos and its major metabolites diethylphosphate, diethylthiophosphate and 3,5,6-trichloro-2-pyridinol in the rat. Toxicology 2007; 237: 145-57.
  • 6. Ladell WS. Physiological and clinical effects of organophosphorus compounds. Proc R Soc Med 1961;54:405-6.
  • 7. Ngamdu YB, Sandabe MB, Kodiya AM, Isa A, Garandawa HI. Sudden Anosmia due to Otapiapia (Organophosphate Pesticide) Exposure. JCR. 2012;2(2):8-9.

Ayrıntılar

Birincil Dil İngilizce
Konular Tıp
Bölüm CASE REPORTS
Yazarlar

Metin BAĞCI> (Sorumlu Yazar)
Selcuk University Faculty of Medicine, Department of Hematology, Konya,Turkey
0000-0003-0877-4505
Türkiye


Serhat SAYİN>
Selcuk University Faculty of Medicine, Department of Hematology, Konya,Turkey
0000-0002-8201-1760
Türkiye


Mehmet DAGLİ>
Selcuk University Faculty of Medicine, Department of Hematology, Konya,Turkey
0000-0002-1338-1776
Türkiye

Teşekkür Çalışmamızı değerlendirmenize sunuyor teşekkür ediyorum.
Yayımlanma Tarihi 30 Eylül 2022
Başvuru Tarihi 15 Haziran 2022
Kabul Tarihi 29 Ağustos 2022
Yayınlandığı Sayı Yıl 2022, Cilt 3, Sayı 3

Kaynak Göster

APA Bağcı, M. , Sayin, S. & Dagli, M. (2022). Heavy hemolysis after organophosphate poisoning by chlorpyrifos ethyl . Archives of Current Medical Research , 3 (3) , 247-249 . Retrieved from https://dergipark.org.tr/tr/pub/acmr/issue/72847/1131153

Archives of Current Medical Research (ACMR) provides instant open access to all content, bearing in mind the fact that presenting research

free to the public supports a greater global exchange of knowledge.

http://www.acmronline.org/