Clinicopathological evaluation of parasitic infections in appendectomy specimens

Yıl 2023, Cilt: 4 Sayı: 1, 40 - 46, 31.01.2023

Murat Kartal Tolga Kalaycı Yaşar Çöpelci Ali Kurt

https://doi.org/10.47482/acmr.1141714

Cited By: 1

Öz

Background: This study aimed to determine the incidence of parasitic infections in adult patients who underwent appendectomy and to evaluate the clinicopathological features of parasitic infections in appendectomy specimens.
Methods: Patients who underwent appendectomy between January 2018 and December 2019 with a pre-diagnosis of acute appendicitis (AA) and reported parasitic infection in appendectomy specimens were evaluated retrospectively. Demographic data, comorbidities, clinical and radiological findings, laboratory results, surgical methods, length of hospital stay, postoperative complications, and histopathological examination reports were analyzed.
Results: 939 adult patients underwent appendectomy with a pre-diagnosis of AA. Upon detecting parasitic infection in the histopathological examination, thirty-one (3.3%) patients were included in this study. Twenty (64.5%) patients were women, and the overall mean age was 31.9 years (18-70 years). Twenty-three (74.2%) patients had Enterobius vermicularis, and 8 (25.8%) patients had Tenia saginata. On laboratory examination, the mean percentage of monocytes was only higher in the Taenia saginata group (0.80 vs. 0.66; p=0.039). Both ultrasonography findings and tomography findings were similar in both groups. The morbidity rate of the study was 12.9% (n=4). There was no difference between the two groups regarding the length of hospital stay and morbidity.
Conclusions: Parasitic infections may cause symptoms mimicking acute appendicitis. It should be kept in mind that even in patients with a diagnosis of parasitic intestinal infection, symptoms may have been caused by acute appendicitis, not solely due to parasitic infection.

Anahtar Kelimeler

Appendectomy, Enterobius vermicularis, Taenia saginata.

Kaynakça

• 1. Wagner M, Tubre DJ, Asensio JA. Evolution and Current Trends in the Management of Acute Appendicitis. Surgical Clinics of North America. 2018;98(5):1005-1023. doi:10.1016/j.suc.2018.05.006
• 2. Marco Ceresoli AZ, Allievi AH. Acute appendicitis: Epidemiology, treatment and outcomes- analysis of 16544 consecutive cases. World Journal of Gastrointestinal Surgery. 2016;8(10):693-699. doi:10.4240/wjgs.v8.i10.693
• 3. Téoule P, Laffolie J de, Rolle U, Reissfelder C. Acute Appendicitis in Childhood and Adulthood. Dtsch Arztebl Int. 2020;117(45):764-774. doi:10.3238/arztebl.2020.0764
• 4. Yabanoglu H, Aytac HO, Turk E, et al. Parasitic Infections of the Appendix as a Cause of Appendectomy in Adult Patients. Turkiye Parazitol Derg. 2014;38(1):12-16. doi:10.5152/tpd.2014.3217
• 5. Doni NY, Gürses G, Şimşek Z, Zeyrek FY. Prevalence and associated risk factors of intestinal parasites among children of farm workers in the southeastern Anatolian region of Turkey. Ann Agric Environ Med. 2015;22(3):438-442. doi:10.5604/12321966.1167709
• 6. Hasan A, Nafie K, El-Sayed S, et al. Enterobius vermicularis in appendectomy specimens; Clinicopathological assessment: Cross sectional study. Annals of Medicine and Surgery. 2020;60:168-172. doi:10.1016/j.amsu.2020.10.057
• 7. Zarbaliyev E, Celik S. Parasitic Appendicitis: A Novel Laparoscopic Approach for the Prevention of Peritoneal Contamination. Canadian Journal of Infectious Diseases and Medical Microbiology. 2018;2018:e3238061. doi:10.1155/2018/3238061
• 8. Di Saverio S, Podda M, De Simone B, et al. Diagnosis and treatment of acute appendicitis: 2020 update of the WSES Jerusalem guidelines. World J Emerg Surg. 2020;15(1):27. doi:10.1186/s13017-020-00306-3
• 9. Tran N, Emuakhagbon V-S, Baker BT, Huerta S. Re-assessing the role of the fecalith in acute appendicitis in adults: case report, case series and literature review. J Surg Case Rep. 2021;2021(1). doi:10.1093/jscr/rjaa543
• 10.Charfi S, Sellami A, Affes A, Yaïch K, Mzali R, Boudawara TS. Histopathological findings in appendectomy specimens: a study of 24,697 cases. Int J Colorectal Dis. 2014;29(8):1009-1012. doi:10.1007/s00384-014-1934-7
• 11.Wendt S, Trawinski H, Schubert S, Rodloff AC, Mössner J, Lübbert C. The Diagnosis and Treatment of Pinworm Infection. Dtsch Arztebl Int. 2019;116(13):213-219. doi:10.3238/arztebl.2019.0213
• 12.Flisser A, Viniegra A-E, Aguilar-Vega L, Garza-Rodriguez A, Maravilla P, Avila G. Portrait of human tapeworms. J Parasitol. 2004;90(4):914-916. doi:10.1645/GE-3354CC
• 13.Altun E, Avci V, Azatcam M. Parasitic infestation in appendicitis. A retrospective analysis of 660 patients and brief literature review. Saudi Med J. 2017;38(3):314-318. doi:10.15537/smj.2017.3.18061
• 14.Gelpke K, Hamminga JTH, van Bastelaar JJ, et al. Reducing the negative appendectomy rate with the laparoscopic appendicitis score; a multicenter prospective cohort and validation study. International Journal of Surgery. 2020;79:257-264. doi:10.1016/j.ijsu.2020.04.041
• 15.Emre A, Akbulut S, Bozdag Z, et al. Routine Histopathologic Examination of Appendectomy Specimens: Retrospective Analysis of 1255 Patients. Int Surg. 2013;98(4):354-362. doi:10.9738/INTSURG-D-13-00098.1
• 16.Luiz do Nascimento Junior P, Teixeira Brandt C, Petroianu A. Differences between inflamed and non inflamed appendices diagnosed as acute appendicitis. Ann Med Surg (Lond). 2021;62:135-139. doi:10.1016/j.amsu.2021.01.044
• 17.Soltani S, Salmanzadeh S, Soltani S, et al. Prevalence of Intestinal Parasitic Infections in the Southwest of Iran: A Four-year Retrospective Study. Infect Disord Drug Targets. 2020;20(6):854-859. doi:10.2174/1871526519666191113105043
• 18.González-Moreno O, Domingo L, Teixidor J, Gracenea M. Prevalence and associated factors of intestinal parasitisation: a cross-sectional study among outpatients with gastrointestinal symptoms in Catalonia, Spain. Parasitol Res. 2011;108(1):87-93. doi:10.1007/s00436-010-2044-2