Global Trends in Prenatal Mosaicism Research: Insights from a Bibliometric Analysis (1980–2023)

Yıl 2025, Cilt: 6 Sayı: 1, 17 - 30, 31.01.2025

Engin Yıldırım , Şengül Yüksel , Yılmaz Çiğremiş , Esra Yavemlier , Ercan Erdoğan

https://doi.org/10.47482/acmr.1600170

Öz

Background: The coexistence of at least two cell lines with different genetic structures (chromosomal or single gene mutation) originating from the same zygote in an organism is defined as mosaicism. This study aimed to present a medical perspective by examining scientific articles published on diagnosis of prenatal mosaicism from a perinatal and genetic perspective with statistical methods.
Methods: The source of our study is the Web of Science (WoS) database. The articles indexed between 1980-2023 were included in our research in the database, and the studies of 2024 were not included since the effect factors are not clear yet. While searching the database, the words “Prenatal Mosaicism” were used as keywords
Results: We reached a total of 2124 publications by analyzing the WoS database using the term "prenatal mosaicism". When the citations of the documents written about prenatal mosaicism are evaluated, we found that the highest citation was made in 2022. Co-citation analysis has shown that there are 9932 authors investigating the issue of prenatal mosaicism. Collaboration and citation collaboration was observed between Mackay Memorial Hospital, National Taiwan University and National Yang Ming University. Prenatal screening and Aneuploidy were found the strongest relationship with prenatal mosaicism.
Conclusions: It is observed that the publications related prenatal mosaicism are associated with prenatal diagnosis and screening and this diagnosis has the highest publication, citation and impact power.

Anahtar Kelimeler

Prenatal Diagnosis, Mosaicism, Genetics, Biblioımetry

Etik Beyan

Ethics approval: Not applicable

Destekleyen Kurum

No financial support has been received from any institution or organization for the study.

Teşekkür

Acknowledgements: I would like to thank to the staff of the obstetrics and gynecology unit for cooperation.

Prenatal Mozaiklik Araştırmalarında Küresel Eğilimler: Bibliyometrik Bir Analizden Çıkan Bilgiler (1980-2023)

Öz

Giriş. Bir organizmada aynı zigottan kaynaklanan farklı genetik yapılara (kromozomal veya tek gen mutasyonu) sahip en az iki hücre kolonunun bir arada bulunması mozaisizm olarak tanımlanmaktadır. Bu çalışma, istatistiksel yöntemlerle perinatal ve genetik açıdan prenatal mozaisizmin tanısı üzerine yayınlanmış bilimsel makaleleri inceleyerek tıbbi bir bakış açısı sunmayı amaçlamıştır.
Yöntemler: Çalışmamızın kaynağı Web of Science (WoS) veri tabanıdır. 1980-2023 yılları arasında veri tabanında indekslenen makaleler araştırmamıza dahil edilmiş olup, etki faktörleri henüz netleşmediği için 2024 yılına ait çalışmalar dahil edilmemiştir. Veri tabanında arama yapılırken anahtar kelime olarak “Prenatal Mozaisizm” kelimeleri kullanılmıştır
Sonuçlar: WoS veri tabanını “prenatal mozaisizm” terimini kullanarak analiz ederek toplam 2124 yayına ulaştık. Doğum öncesi mozaisizm hakkında yazılmış yayınların atıfları değerlendirildiğinde, en yüksek atıfın 2022 yılında yapıldığını bulduk. Ortak atıf analizi, doğum öncesi mozaisizmi araştıran 9932 yazar olduğunu gösterdi. Mackay Memorial Hastanesi, Ulusal Tayvan Üniversitesi ve Ulusal Yang Ming Üniversitesi arasında iş birliği ve atıf iş birliği gözlemlendi. Doğum öncesi tarama ve Aneuploidinin doğum öncesi mozaisizm ile en güçlü ilişkisi bulundu.
Sonuçlar: Doğum öncesi mozaisizm ile ilgili yayınların doğum öncesi tanı ve tarama ile ilişkili olduğu ve bu tanının en yüksek yayın, atıf ve etki gücüne sahip olduğu görülmektedir.

Anahtar Kelimeler

prenatal tanı, Mozaisizm, Genetik, Bibliometri

Kaynakça

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