Öz
OBJECTIVE: The purpose of this study is to give the information on the outcome, management and survivability of patients with low extremity liposarcoma.METHODS: This study is a retrospective study. All the patients were seen and managed between 1986 and 2010. Their records were retrieved and analyzed for this study. Fiftynine cases were identified to have the follow up of minimum 5 years and complete documentation. RESULTS: In our study, the most common variant of the liposarcom is mixoid liposarcoma in spite of literature. Ten patients who have low grade liposarcom were treated with marginal resection. Recurrence wasn't observed. We didn't perform neoadjuvant radiotherapy. Two patients who have high grade liposarcoma underwent neoadjuvant chemotherapy. Adjuvant radiotherapy was given 49 patient who have intermediate or high grade liposarcoma. Four patients who have high grade liposarcoma were presented with lung metastases. Two patients who have myxoid liposarcoma were presented with extremity metastates.CONCLUSION: We thought that, low grade liposarcomas had been treated at other small clinics as lipom so in our series the myxoid liposarcoma is the most common subtype. Neoadjuvant radiotherapy can get difficult surgery done. Recurrence usually was presented in two years after first surgery. So patients must be followed frequently during two years.
Anahtar Kelimeler
Kaynakça
- Enzinger FM, Weiss SW, eds. Soft Tissue Tumors. 3rd ed. StLouis: Mosby 1995:431-66
- Issakov J, Soyfer V, Kollender Y, et al. Liposarcoma in adult limbs treated by limb-sparing surgery and adjuvant radiotherapy. J Bone Joint Surg Br 2006; 88:1647-51 3. Evans HL. Liposarcoma. A study of 55 cases with a reassessment of its classification. Am J Surg Pathol 1979;3:507-23 4. Spittle MF, Newton KA, Mackenzie
- DH. Liposarcoma. A reviewof 60 cases. Br J Cancer 1970; 24:696-704 5. Orson GG, Sim FH, Reiman HM, Taylor WF. Liposarcoma of the musculoskeletal system. Cancer 1987;60:1362-70
Öz
AMAÇ: Bu çalışmada alt ekstremite liposarkomları hakkında bilgi vermek,tedavi yönetimi ve hastaların ortalam yaşam süreleri hakkında klinik tecrübelerimizin paylaşılması amaçlanmıştır.YÖNTEMLER: Retrospektif bir çalışmadır.1986-2010 yılları arasında minimum takip süresi 5 yıl ve daha fazla olan 59 hastanın dosyaları ve radyolojik görünütleri incelenmiştir.BULGULAR: Bizim çalışmamızda literatürün aksine en sık görülen liposarkom alttipi miksoid liposarkom oalrak belirlenmiştir. Low grade liposarkom olan 10 hasta sadece marginal rezeksiyon ile tedavi edilip nüks izlenmemiştir. Hiçbir hastaya neoadjuvan radyoterapi verilmemiştir. Adjuvan Radyoterapi ise intermediate grade ve high grade liposarkom olan diğer 49 hastaya verilmiştir. High grade liposarkom olan 4 hastada akciğer metastazı gözlenmiştir. Miksoid lposarkom olan 2 hastada ise ekstremite metastazı gözlenmiştir.SONUÇ: Miksoid liposarkom alttipinin kliniğimizde en fazla oranda görülmesinin sebebinin, low grade liposarkomların lipom gibi birçok kinikte tedavisinin yapılması olarak düşünüyoruz. Neoadjuvan radyoterapinin cerrahiyi tedaviyi zorlaştırabileceğinden verilmemiştir. Nükslerin çoğunlukla ilk 2 yıl içinde görülmektedir bundan dolayı ilk 2 yıl boyunca hastaların sıkı takip edilmelidir.
Anahtar Kelimeler
Kaynakça
- Enzinger FM, Weiss SW, eds. Soft Tissue Tumors. 3rd ed. StLouis: Mosby 1995:431-66
- Issakov J, Soyfer V, Kollender Y, et al. Liposarcoma in adult limbs treated by limb-sparing surgery and adjuvant radiotherapy. J Bone Joint Surg Br 2006; 88:1647-51 3. Evans HL. Liposarcoma. A study of 55 cases with a reassessment of its classification. Am J Surg Pathol 1979;3:507-23 4. Spittle MF, Newton KA, Mackenzie
- DH. Liposarcoma. A reviewof 60 cases. Br J Cancer 1970; 24:696-704 5. Orson GG, Sim FH, Reiman HM, Taylor WF. Liposarcoma of the musculoskeletal system. Cancer 1987;60:1362-70
Ayrıntılar
| Birincil Dil | Türkçe |
|---|---|
| Bölüm | Makaleler |
| Yazarlar | |
| Yayımlanma Tarihi | 1 Nisan 2013 |
| Yayımlandığı Sayı | Yıl 2013 |