BibTex RIS Kaynak Göster
Yıl 2016, Cilt: 2 Sayı: 3, 41 - 46, 01.10.2016

Öz

Background: Proliferative verrucous leukoplakia
(PVL) is the rarest and stubborn subtype of oral
leukoplakia (OL). The origin of PVL is still unknown
and because the possible risk factors of OL are not in
complete accordance with PVL, diagnosing the disease
is very hard. PVL also needs special attention because
of the high progression rate of squamous cell carcinoma
and verrucous carcinoma.
Case Report: A 54 year old female patient was admitted
to our department with the complaint of painless white
lesions in anterior region of the floor of the mouth.
In the light of the clinical and radiological findings,
with the initial OL diagnosis, lesion was excised using
electrocautery as a whole under local anesthesia and
sent for histopathological examination. Final diagnosis
was “Proliferative Verrucous Hyperplasia”. After 60
months of follow-up, there was no recurrence.
Conclusion and Clinical Relevance: Since PVL
has high progression rate for malign lesions and high
relapse rates, it is important to detect the disease at
early stages, and long term follow-up after surgical
excision is needed

Kaynakça

  • Lodi G, Sardella A, Bez C, Demarosi F, Carrassi A. Interventions for treating oral leukoplakia. The Cochrane database of systematic reviews. 2006(4):CD001829.
  • Kumar A, Cascarini L, McCaul JA, Kerawala CJ, Coombes D, Godden D, et al. How should we manage oral leukoplakia? The British journal of oral & maxillofacial surgery. 2013;51(5):377- 83.
  • Hansen LS, Olson JA, Silverman S, Jr. Proliferative verrucous leukoplakia. A long- term study of thirty patients. Oral surgery, oral medicine, and oral pathology. 1985;60(3):285- 98.
  • Abadie WM, Partington EJ, Fowler CB, Schmalbach CE. Optimal Management of Proliferative Verrucous Leukoplakia: A Systematic Review of the Literature. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery. 2015;153(4):504-11.
  • Gillenwater AM, Vigneswaran N, Fatani H, Saintigny P, El-Naggar AK. Proliferative verrucous leukoplakia: recognition and differentiation from conventional leukoplakia and mimics. Head & neck. 2014;36(11):1662-8.
  • Cerero-Lapiedra R, Balade-Martinez D, Moreno-Lopez LA, Esparza-Gomez G, Bagan JV. Proliferative verrucous leukoplakia: a proposal for diagnostic criteria. Medicina oral, patologia oral y cirugia bucal. 2010;15(6):e839- 45.
  • Batsakis JG, Suarez P, el-Naggar AK. Proliferative verrucous leukoplakia and its related lesions. Oral oncology. 1999;35(4):354- 9.
  • Pentenero M, Meleti M, Vescovi P, Gandolfo S. Oral proliferative verrucous leucoplakia: are there particular features for such an ambiguous entity? A systematic review. The British journal of dermatology. 2014;170(5):1039-47.
  • Silverman S, Jr., Gorsky M. Epidemiologic and demographic update in oral cancer: California and national data--1973 to 1985. Journal of the American Dental Association. 1990;120(5):495- 9.
  • Gandolfo S, Castellani R, Pentenero M. Proliferative verrucous leukoplakia: a potentially malignant disorder involving periodontal sites. Journal of periodontology. 2009;80(2):274-81.
  • Silverman S, Jr., Gorsky M, Lozada F. Oral leukoplakia and malignant transformation.
  • A follow-up study of 257 patients. Cancer. 1984;53(3):563-8.

PROLIFERATIVE VERRUCOUS LEUKOPLAKIA: FIVE YEARS FOLLOW-UP

Yıl 2016, Cilt: 2 Sayı: 3, 41 - 46, 01.10.2016

Öz

Background: Proliferative verrucous leukoplakia
(PVL) is the rarest and stubborn subtype of oral
leukoplakia (OL). The origin of PVL is still unknown
and because the possible risk factors of OL are not in
complete accordance with PVL, diagnosing the disease
is very hard. PVL also needs special attention because
of the high progression rate of squamous cell carcinoma
and verrucous carcinoma.
Case Report: A 54 year old female patient was admitted
to our department with the complaint of painless white
lesions in anterior region of the floor of the mouth.
In the light of the clinical and radiological findings,
with the initial OL diagnosis, lesion was excised using
electrocautery as a whole under local anesthesia and
sent for histopathological examination. Final diagnosis
was “Proliferative Verrucous Hyperplasia”. After 60
months of follow-up, there was no recurrence.
Conclusion and Clinical Relevance: Since PVL
has high progression rate for malign lesions and high
relapse rates, it is important to detect the disease at
early stages, and long term follow-up after surgical
excision is needed

Kaynakça

  • Lodi G, Sardella A, Bez C, Demarosi F, Carrassi A. Interventions for treating oral leukoplakia. The Cochrane database of systematic reviews. 2006(4):CD001829.
  • Kumar A, Cascarini L, McCaul JA, Kerawala CJ, Coombes D, Godden D, et al. How should we manage oral leukoplakia? The British journal of oral & maxillofacial surgery. 2013;51(5):377- 83.
  • Hansen LS, Olson JA, Silverman S, Jr. Proliferative verrucous leukoplakia. A long- term study of thirty patients. Oral surgery, oral medicine, and oral pathology. 1985;60(3):285- 98.
  • Abadie WM, Partington EJ, Fowler CB, Schmalbach CE. Optimal Management of Proliferative Verrucous Leukoplakia: A Systematic Review of the Literature. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery. 2015;153(4):504-11.
  • Gillenwater AM, Vigneswaran N, Fatani H, Saintigny P, El-Naggar AK. Proliferative verrucous leukoplakia: recognition and differentiation from conventional leukoplakia and mimics. Head & neck. 2014;36(11):1662-8.
  • Cerero-Lapiedra R, Balade-Martinez D, Moreno-Lopez LA, Esparza-Gomez G, Bagan JV. Proliferative verrucous leukoplakia: a proposal for diagnostic criteria. Medicina oral, patologia oral y cirugia bucal. 2010;15(6):e839- 45.
  • Batsakis JG, Suarez P, el-Naggar AK. Proliferative verrucous leukoplakia and its related lesions. Oral oncology. 1999;35(4):354- 9.
  • Pentenero M, Meleti M, Vescovi P, Gandolfo S. Oral proliferative verrucous leucoplakia: are there particular features for such an ambiguous entity? A systematic review. The British journal of dermatology. 2014;170(5):1039-47.
  • Silverman S, Jr., Gorsky M. Epidemiologic and demographic update in oral cancer: California and national data--1973 to 1985. Journal of the American Dental Association. 1990;120(5):495- 9.
  • Gandolfo S, Castellani R, Pentenero M. Proliferative verrucous leukoplakia: a potentially malignant disorder involving periodontal sites. Journal of periodontology. 2009;80(2):274-81.
  • Silverman S, Jr., Gorsky M, Lozada F. Oral leukoplakia and malignant transformation.
  • A follow-up study of 257 patients. Cancer. 1984;53(3):563-8.
Toplam 12 adet kaynakça vardır.

Ayrıntılar

Diğer ID JA59FZ29MK
Bölüm Araştırma Makalesi
Yazarlar

Behçet Erol Bu kişi benim

Sercan Küçükkurt Bu kişi benim

Tuğçe Biçer Aytugar Bu kişi benim

Nihan Aksakallı Bu kişi benim

Yayımlanma Tarihi 1 Ekim 2016
Gönderilme Tarihi 1 Ekim 2016
Yayımlandığı Sayı Yıl 2016 Cilt: 2 Sayı: 3

Kaynak Göster

Vancouver Erol B, Küçükkurt S, Aytugar TB, Aksakallı N. PROLIFERATIVE VERRUCOUS LEUKOPLAKIA: FIVE YEARS FOLLOW-UP. Aydin Dental Journal. 2016;2(3):41-6.

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