FOTO-AKTİF DEZENFEKSİYONDA KULLANILAN FARKLI FOTOSENSİTİZÖR MADDELERİN ANTİMİKROBİYAL ETKİSİNİN EX VİVO OLARAK İNCELENMESİ

Yıl 2017, Cilt: 3 Sayı: 2, 3 - 12, 02.10.2017

Serap Akyüz

Öz

 Amaç: Çalışmamızın amacı foto-aktif dezenfeksiyon tekniği ile kullanılan güncel fotosensitizörlerin, antimikrobiyal aktivitelerinin kavite dezenfeksiyonunda altın standart olarak kabul edilen klorheksidin diglukonat ile karşılaştırılmasıdır. Gereç ve yöntem: Çalışmamızda üç farklı fotosensitizör (hiperisin, oligomerik proantosiyanidin, rumex cristatus DC.) iki farklı ışık kaynağı ile aktive edildi (Elipar S10 LED™, Fotosan 630 LAD®) ve sonuçlar klorheksidin diglukonat ile karşılaştırıldı. Çalışmada çekimi yapılan 70 adet süt dişinden tedavi öncesi ve sonrası dentin örnekleri alındı ve hazır agarlara ekilerek inkübasyon sonrası antimikrobiyal etkisi değerlendirildi. Bulgular: Hiperisin ve rumex cristatus DC.’nin fotosensitizör olarak antimikrobiyal etkisi klorheksidine göre daha yüksek ancak, oligomerik proantosiyanidinin daha düşük bulundu. Fotosensitizör maddelerin foto-aktivasyonu için kullanılan ışık kaynaklarından LED ışık cihazı daha başarılı sonuçlar verdi. Sonuç: Çalışmamızın sonucuna göre fotosensitizör olarak hiperisin ve rumex cristatus DC.’nin LED ışık cihazı ile aktivasyonunun kavite dezenfeksiyonunda kullanılabileceği düşünülmektedir

Anahtar Kelimeler

Foto-aktif dezenfeksiyon, kavite dezenfeksiyonu, Hypericum perforatum, oligomerik proantosiyanidin

Kaynakça

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