Dentinogenic Ghost‑Cell Tumor: An Uncommon Entity

Yıl 2024, Cilt: 10 Sayı: 2, 211 - 216, 16.08.2024

Görkem Tekin , Nesrin Saruhan , Ömür Dereci , Yasin Koşar , Melek Gürbüz , Fuat Açıkalın

Öz

Introduction: Dentinogenic Ghost Cell Tumor (DGCT) constitutes less than 3% of all odontogenic tumors, making it a rare entity characterized by local invasion. The histopathological features of DGCT are the presence of ghost cell layers and formation of dentinoid material with an ameloblastoma-like odontogenic epithelial proliferation. The peripheral variant of DGCT behaves less aggressively than the intraosseous variant and usually occurs on the anterior region of both jaws.
Case Report: A 60-year-old male patient was referred to the oral and maxillofacial surgery clinic with a complaint of a painless swelling extending from the left upper molar region to the canine region. In the radiographic examination, destruction was observed in the maxillary bone where the lesion was located. Incisional biopsy revealed the diagnosis of DGCT. The patient was scheduled for surgery, but the lesion could not be excised because he refused the treatment.
Conclusion: DGCT may present as a malignant-like lesion in the maxillary posterior region. Therefore, histopathological differential diagnosis must be made.

Anahtar Kelimeler

Ghost Cell, Maxilla, Oral Cavity, Tumor

Dentinojenik Hayalet Hücre Tümör: Yaygın Olmayan Entite

Öz

Amaç: Dentinojenik hayalet hücreli tümör (DHHT), tüm odontojenik tümörlerin %3'ünden azını oluşturur ve bu da onu lokal invazyonla karakterize nadir bir antite haline getirmektedir. DHHT'nin histopatolojik özellikleri, hayalet hücre tabakalarının varlığı ve dentinoid materyalin oluşumu ile ameloblastoma benzeri odontojenik epitelyal proliferasyonudur. DHHT'nin periferik varyantı, intraosseöz varyantına göre daha az agresif davranır ve genellikle her iki çenenin ön bölgesinde görülmektedir.
Olgu Sunumu: 60 yaşındaki erkek hasta, sol üst çene molar bölgesinden kanin bölgesine kadar uzanan ağrısız şişlik şikayeti ile ağız, diş ve cerrahisi kliniğine yönlendirildi. Radyografik incelemede, lezyonun bulunduğu üst çene kemiğinde rezorpsiyon gözlendi. İnsizyonel biyopsi sonucunda DHHT tanısı konuldu. Hasta ameliyat için planlandı ancak tedaviyi reddettiği için lezyon çıkarılamadı.
Sonuç: DHHT, maksiller posterior bölgede malign benzeri bir lezyon olarak ortaya çıkabilir. Bu nedenle mutlaka histopatolojik ayırıcı tanı yapılmalıdır.

Anahtar Kelimeler

Hayalet Hücre, Maksilla, Oral kavite, Tümör

Kaynakça

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