BibTex RIS Kaynak Göster

Masticatory Muscle Myopathy in a Dog

Yıl 2013, Cilt: 2 Sayı: 1, 159 - 161, 01.01.2013

Öz

A 2,5 years old mixed breed male dog presenting complaints of inability to open the mouth, drooling, with no food and water consumption 3 days prior to referral was enrolled in the present article. Dehydration, bilateral severe swelling of the temporal and masseter muscles and constant pytyalism were detected at physical examination. Body temperature was within the reference ranges and neither orthopedic nor neurologic abnormalities were detected. Complate blood cell count did not show abnormalities other than eosinophilia of 2170/ml. Clinic and histopathologic findings indicated masticatory muscle myopathy. Initial treatment included prednisone 1 mg/kg/12h, i.m. and procain peniciline 20000 IU/kg/day, i.m. administrations. Related clinical signs were regressed following 3 days of therapy. The case regained normal jaw motions albeit severe atrophy was evident in masseter and temporal muscles. Almost 2 months later, the case was readmitted with similar symptoms, because of withdrawal of recommended drugs by the owner himself. Supportive therapy included dexamethasone 0.15 mg/kg, p.o. for 15 days . Jaw functions recovered within 4 days and were still normal after six months. As a result, it was concluded that immune-mediated inflammation of muscles of mastication in dogs may be treated with use of steroids for a long period, albeit in case of early withdrawal of therapy, recurrence may observed, following initial recovery swelling and severe atrophy could be developed on masticatory musles whereas this conditon may not limit jaw mobility.

Kaynakça

  • Gilmour MA, Morgan RV, Moore FM (1992). Masticatory myopathy in the dog: a retrospective study of 18 cases. Journal of the American Animal Hospital Association, pp. 28, 300-306.
  • Glauberg B, Beaumont PR (1979). Sudden blindness as the presenting sign of eosinophilic myositis: a case report. Journal of the American Animal Hospital Association, 15, pp. 609-610.
  • Griffiths IR, Duncan ID, McQueen A, Quirk C, Miller R (1973). Neuro- muscular disease in dogs: some aspects of its investigation and di- agnosis. Journal of Small Animal Practice, 14, 533-54.
  • Lecoueur AV (1989). Disorders of the skeletal muscles. In: Textbook of Veterinary Internal Medicine, 3rd Edit., Ettinger SJ (Ed), Philadel- phia, WB Saunders, pp. 741-742.
  • Lewis RM. Immune-mediated muscle disease. Vet Clin North Am Small Anim Pract 1994;24:703–710.
  • McKeown D, Archibald J (1979). Musculoskelatal system. In: Canine Medicine, Catcott EJ (Ed), American Veterinary Publications, Santa Barbara, pp. 660-663.
  • Orvis JS, Cardinet GH (1981). Canine muscle fiber types and suscepti- bility of masticatory muscles to myositis. Muscle Nerve, 4, pp. 354- 359.
  • Pedroia V (1989). Disorders of the skeletal muscles. In: Textbook of Vet- erinary Internal Medicine, 3rd Edit, Ettinger SJ (Ed), WB Saunders, Philadelphia, pp. 741-742.
  • Shelton GD: Canine masticatory muscle disorders, in Kirks RW (ed): Current Veterinary Therapy X. Philadelphia, WB Saunders, 1989, pp 816–819.
  • Shelton GD: Pathophysiologic basis of canine muscle disorders. J Vet Intern Med 1:36–44, 1987.
  • Shelton DG, Cardinet III GH, Bandman E. Canine masticatory muscle disorders: a study of 29 cases. Muscle Nerve 1987;10:753–766.
  • Shelton GD, Cardinet GH, Bandman E, Cuddon P (1985). Fiber type-spe- cific autoantibodies in a dog with eosinophilic myositis. Muscle Nerve, 8, pp. 783-790.
  • Smith MO (1989). Idiopathic myositis in dogs. Seminars in Veterinary Medicine & Surgery (Small Animal), 4, pp. 156-160.
  • Taylor SM. Selected disorders of the muscle and the neuromuscular junction. Vet Clin North Am Small Anim Pract 2000;30:59–75.
  • Turgut K (2000). Veteriner Klinik Laboratuvar Teşhis, Genişletilmiş 2. baskı. Bahçıvanlar Basım Sanayi AŞ, Konya, pp. 885-886.
  • Vilafranca M, Wohlsein P, Borras D, Pumarola M, Domingo M (1995). Muscle fibre expression of transforming growth factor-β1 and la- tent transforming growth factor-β binding protein in canine masti- catory muscle myositis. Journal of Comparative Pathology, 112, pp. 299-306.

Bir Köpekte Çiğneme Kası Miyopatisi

Yıl 2013, Cilt: 2 Sayı: 1, 159 - 161, 01.01.2013

Öz

Bu makalede, 3 gündür ağız açmada, gıda ve su alımında güçlük ve ağız akıntısı şikâyetiyle kliniğimize getirilen bir köpek 30 aylık, 22 kg ağırlığında, erkek, melez ele alındı. Klinik muayenede dehidrasyon, temporal ve masseter kaslarında bilateral şiddetli şişkinlik ve sürekli salya akıntısı belirlendi. Vücut ısısı referans değerler içerisindeydi. Ortopedik ve nörolojik herhangi bir bozukluk saptanmadı. Hastada periferal eozinofili 2170/ml bulunması dışında tam kan sayımında herhangi bir anormalite saptanmadı. Klinik ve laboratuar bulguları ile birlikte masseter kasından alınan biyopsi örneklerinin histopatolojik muayene sonuçları rehberliğinde çiğneme kası miyozitisi teşhis edildi. Prokain penisilin 20000 IU/kg, gün, i.m. ve prednizolon 1 mg/kg, 12s, i.m. uygulaması ile tedaviye başlandı. Üç gün sonra klinik bulgularda gerileme görüldü. Hasta, normal çene fonksiyonlarını tekrar kazandı, bununla birlikte masseter ve temporal kaslarda şiddetli atrofi gözlendi. Yaklaşık iki ay sonra, sahibi ilaç uygulamasını önerilen zamandan daha erken kestiği için, hasta başlangıçtakine benzer bulgularla tekrar başvurdu. Tedaviye dekzametazon 0.15 mg/kg, p.o., 15 gün ile tekrar başlandı. Altı ay sonra hasta sahibi ile yapılan telefon görüşmelerinde köpeğin normal çene fonksiyonlarına sahip olduğu öğrenildi. Sonuç olarak, köpeklerde immun aracılı çiğneme kası miyozitisin uzun süreli steroid kullanımı ile tedavi edilebileceği, fakat tedavi erken kesilirse nüks olayların görülebileceği, iyileşmeden sonra çiğneme kaslarında şişlik ve şiddetli atrofiler şekillenebileceği, ancak bunların çene hareketlerini kısıtlamayabileceği kararına varıldı.

Kaynakça

  • Gilmour MA, Morgan RV, Moore FM (1992). Masticatory myopathy in the dog: a retrospective study of 18 cases. Journal of the American Animal Hospital Association, pp. 28, 300-306.
  • Glauberg B, Beaumont PR (1979). Sudden blindness as the presenting sign of eosinophilic myositis: a case report. Journal of the American Animal Hospital Association, 15, pp. 609-610.
  • Griffiths IR, Duncan ID, McQueen A, Quirk C, Miller R (1973). Neuro- muscular disease in dogs: some aspects of its investigation and di- agnosis. Journal of Small Animal Practice, 14, 533-54.
  • Lecoueur AV (1989). Disorders of the skeletal muscles. In: Textbook of Veterinary Internal Medicine, 3rd Edit., Ettinger SJ (Ed), Philadel- phia, WB Saunders, pp. 741-742.
  • Lewis RM. Immune-mediated muscle disease. Vet Clin North Am Small Anim Pract 1994;24:703–710.
  • McKeown D, Archibald J (1979). Musculoskelatal system. In: Canine Medicine, Catcott EJ (Ed), American Veterinary Publications, Santa Barbara, pp. 660-663.
  • Orvis JS, Cardinet GH (1981). Canine muscle fiber types and suscepti- bility of masticatory muscles to myositis. Muscle Nerve, 4, pp. 354- 359.
  • Pedroia V (1989). Disorders of the skeletal muscles. In: Textbook of Vet- erinary Internal Medicine, 3rd Edit, Ettinger SJ (Ed), WB Saunders, Philadelphia, pp. 741-742.
  • Shelton GD: Canine masticatory muscle disorders, in Kirks RW (ed): Current Veterinary Therapy X. Philadelphia, WB Saunders, 1989, pp 816–819.
  • Shelton GD: Pathophysiologic basis of canine muscle disorders. J Vet Intern Med 1:36–44, 1987.
  • Shelton DG, Cardinet III GH, Bandman E. Canine masticatory muscle disorders: a study of 29 cases. Muscle Nerve 1987;10:753–766.
  • Shelton GD, Cardinet GH, Bandman E, Cuddon P (1985). Fiber type-spe- cific autoantibodies in a dog with eosinophilic myositis. Muscle Nerve, 8, pp. 783-790.
  • Smith MO (1989). Idiopathic myositis in dogs. Seminars in Veterinary Medicine & Surgery (Small Animal), 4, pp. 156-160.
  • Taylor SM. Selected disorders of the muscle and the neuromuscular junction. Vet Clin North Am Small Anim Pract 2000;30:59–75.
  • Turgut K (2000). Veteriner Klinik Laboratuvar Teşhis, Genişletilmiş 2. baskı. Bahçıvanlar Basım Sanayi AŞ, Konya, pp. 885-886.
  • Vilafranca M, Wohlsein P, Borras D, Pumarola M, Domingo M (1995). Muscle fibre expression of transforming growth factor-β1 and la- tent transforming growth factor-β binding protein in canine masti- catory muscle myositis. Journal of Comparative Pathology, 112, pp. 299-306.
Toplam 16 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Bölüm Research Article
Yazarlar

Murat Sarıerler Bu kişi benim

Zeynep Bozkan Tatlı Bu kişi benim

Bahar Bayraktar Bu kişi benim

Yayımlanma Tarihi 1 Ocak 2013
Yayımlandığı Sayı Yıl 2013 Cilt: 2 Sayı: 1

Kaynak Göster

APA Sarıerler, M., Tatlı, Z. B., & Bayraktar, B. (2013). Masticatory Muscle Myopathy in a Dog. Animal Health Production and Hygiene, 2(1), 159-161.