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Endoscopic clipping for non-variceal upper gastrointestinal bleeding

Yıl 2014, Cilt: 13 Sayı: 1, 13 - 17, 01.04.2014

Öz

Background and Aims: Endoscopic clipping has been widely used for upper gastrointestinal bleeding. It has been shown that hemostasis with endoscopic clipping is successful in bleeding peptic ulcers, Dieulafoy's lesions, and Mallory-Weiss tears. The aim of this study was to evaluate the efficacy of endoscopic clipping in our endoscopy unit. Materials and Methods: Patients presenting with upper gastrointestinal bleeding were evaluated retrospectively. Twenty-seven patients were treated with endoscopic clipping. The etiology of bleeding, rebleeding rates, need for packed red blood cell transfusion, mortality rate, and the Rockall and Glasgow-Blatchford scores were noted. Results:The mean age of the patients (17 male, 10 female) was 58,7 years. Five patients had gastric ulcer (1 Forrest 1a, 2 Forrest 1b, 2 Forrest 2a), 10 patients duodenal ulcer (5 Forrest 1b, 5 Forrest 2a), 7 patients MalloryWeiss tears, and 4 patients Dieulafoy's lesion as the etiology of upper gastrointestinal bleeding. One patient had Forrest 2a duodenal ulcer and Mallory-Weiss tears. Two of the patients (7,4%) rebled. Nineteen patients needed packed red blood cell transfusion with a total of 72 units. The mean Rockall score was 2,9 and the mean Glasgow-Blatchford score was 8,5. Conclusions:Although our patient population was high-risk, the rebleeding rate was low, and none of the patients died.

Kaynakça

  • Sung JJ, Tsoi KK, Lai LH, et al. Endoscopic clipping versus injec- tion and thermo-coagulation in the treatment of non-variceal upper gastrointestinal bleeding: a meta-analysis. Gut 2007; 56:1364-73.
  • Yamaguchi Y, Yamato T, Katsumi N, et al. Endoscopic hemoclip- ping for upper GI bleeding due to Mallory-Weiss syndrome. Gastro- intest Endosc 2001; 53:427-30.
  • Chung IK, Kim EJ, Lee MS, et al. Bleeding Dieulafoy’s lesions and the choice of endoscopic method: comparing the hemostatic ef- ficacy of mechanical and injection methods. Gastrointest Endosc 2000; 52:721-4.
  • Forrest JA, Finlayson ND, Shearman DJ. Endoscopy in gastrointesti- nal bleeding. Lancet 1974; 2:394-7.
  • Dy NM, Gostout CJ, Balm RK. Bleeding from the endoscopically- identified Dieulafoy lesion of the proximal small intestine and co- lon. Am J Gastroenterol 1995; 90:108-11.
  • Rockall TA, Logan RF, Devlin HB, Northfield TC. Selection of pa- tients for early discharge or outpatient care after acute upper gas- trointestinal haemorrhage. National Audit of Acute Upper Gastro- intestinal Haemorrhage. Lancet 1996; 347:1138-40.
  • Blatchford O, Murray WR, Blatchford M. A risk score to predict need for treatment for upper-gastrointestinal haemorrhage. Lancet 2000; 356:1318-21.
  • Murphy MF, Wallington TB, Kelsey P, et al. British Committee for Standards in Haematology, Blood Transfusion Task Force. Guide- lines for the clinical use of red cell transfusions. Br J Haematol 2001; 113:24-31.
  • Hayashi T, Yonezawa M, Kawabara T. The study on staunch clip for the treatment by endoscopy. Gastroenterol Endosc 1975;17:92- 101.
  • Hokama A, Uehara T, Nakayoshi T, et al. Utility of endoscopic he- moclipping for colonic diverticular bleeding. Am J Gastroenterol 1997; 92:543-6.
  • Parra-Blanco A, Kaminaga N, Kojima T, et al. Hemoclipping for postpolypectomy and postbiopsy colonic bleeding. Gastrointest Endosc 2000; 51:37-41.
  • Tsunada S, Ogata S, Ohyama T, et al. Endoscopic closure of per- forations caused by EMR in the stomach by application of metallic clips. Gastrointest Endosc 2003; 57:948-51.
  • Cipolletta L, Bianco MA, Marmo R, ve ark. Endoclips versus heater probe in preventing early recurrent bleeding from peptic ulcer: a prospective and randomized trial. Gastrointest Endosc 2001;53:147-51.
  • Lin HJ, Hsieh YH, Tseng GY, et al. A prospective randomized trial of endoscopic hemoclip versus heater probe thermocoagulation for peptic ulcer bleeding. Am J Gastroenterol 2002; 97:2250-4.
  • Yuan Y, Wang C, Hunt RH. Endoscopic clipping for acute nonvari- ceal upper-GI bleeding: a meta-analysis and critical appraisal of ran- domized controlled trials. Gastrointest Endosc 2008; 68:339-51.
  • Huang SP, Wang HP, Lee YC, et al. Endoscopic hemoclip placement and epinephrine injection for Mallory-Weiss syndrome with active bleeding. Gastrointest Endosc 2002; 55:842-6.
  • Park CH, Sohn YH, Lee WS, et al. The usefulness of endoscopic hemoclipping for bleeding Dieulafoy lesions. Endoscopy 2003: 35:388-92.

Varis dışı üst GİS kanamalı hastalarda endoskopik klip uygulamalarımız

Yıl 2014, Cilt: 13 Sayı: 1, 13 - 17, 01.04.2014

Öz

Giriş ve Amaç: Endoskopik klip uygulaması üst gastrointestinal sistem kanaması tedavisinde yaygın olarak kullanılmaktadır. Kanayan peptik ülser, Dieulafoy lezyonu ve Mallory-Weiss yırtığında klip ile kanama kontrolünün sağlanabileceği gösterilmiştir. Biz bu çalışmada kliniğimizin üst gastrointestinal sistem kanamasında endoskopik klip uygulama verilerini değerlendirdik. Gereç ve Yöntem:Üst gastrointestinal sistem kanaması nedeniyle yatırılan ve endoskopik klip uygulanan 27 hasta retrospektif olarak incelendi. Klip uygulama nedenleri, tekrar kanama sıklığı, eritrosit süspansiyon ihtiyaçları, mortalite sıklığı, Rockall skoru ve Glasgow-Blatchford skoru değerlendirildi. Bulgular:Çalışmaya dahil edilen hastaların 17'si erkek, 10'u kadın idi ve yaş ortalaması 58,7 yıl olarak hesaplandı. Klip uygulanan 5 hastada gastrik ülser (1 hasta Forrest 1a, 2 hasta Forrest 1b, 2 hasta Forrest 2a); 10 hastada duodenal ülser (5 hasta Forrest 1b, 5 hasta Forrest 2a); 7 hastada Mallory-Weiss yırtığı ve 4 hastada Dieulafoy lezyonu üst gastrointestinal sistem kanamasının nedeni idi. Hastalardan birinde ise hem Forrest 2a duodenum ülseri hem de Mallory-Weiss yırtığı mevcuttu. 27 hastanın 2'sinde (%7,4) işlem sonrası takip sırasında kanama tekrarladı. Hastaların 19'unda (%70) eritrosit süspansyonu ihtiyacı oldu ve toplam 72 ünite ES verildi. Hastaların ortalama Rockall skoru 2,9 ve ortalama Glasgow-Blatchford skoru 8,5 idi. Sonuç: Prognoz açısından riskli olan hastalarımızda mortalite saptanmamış ve tekrar kanama riski düşük bulunmuştur.

Kaynakça

  • Sung JJ, Tsoi KK, Lai LH, et al. Endoscopic clipping versus injec- tion and thermo-coagulation in the treatment of non-variceal upper gastrointestinal bleeding: a meta-analysis. Gut 2007; 56:1364-73.
  • Yamaguchi Y, Yamato T, Katsumi N, et al. Endoscopic hemoclip- ping for upper GI bleeding due to Mallory-Weiss syndrome. Gastro- intest Endosc 2001; 53:427-30.
  • Chung IK, Kim EJ, Lee MS, et al. Bleeding Dieulafoy’s lesions and the choice of endoscopic method: comparing the hemostatic ef- ficacy of mechanical and injection methods. Gastrointest Endosc 2000; 52:721-4.
  • Forrest JA, Finlayson ND, Shearman DJ. Endoscopy in gastrointesti- nal bleeding. Lancet 1974; 2:394-7.
  • Dy NM, Gostout CJ, Balm RK. Bleeding from the endoscopically- identified Dieulafoy lesion of the proximal small intestine and co- lon. Am J Gastroenterol 1995; 90:108-11.
  • Rockall TA, Logan RF, Devlin HB, Northfield TC. Selection of pa- tients for early discharge or outpatient care after acute upper gas- trointestinal haemorrhage. National Audit of Acute Upper Gastro- intestinal Haemorrhage. Lancet 1996; 347:1138-40.
  • Blatchford O, Murray WR, Blatchford M. A risk score to predict need for treatment for upper-gastrointestinal haemorrhage. Lancet 2000; 356:1318-21.
  • Murphy MF, Wallington TB, Kelsey P, et al. British Committee for Standards in Haematology, Blood Transfusion Task Force. Guide- lines for the clinical use of red cell transfusions. Br J Haematol 2001; 113:24-31.
  • Hayashi T, Yonezawa M, Kawabara T. The study on staunch clip for the treatment by endoscopy. Gastroenterol Endosc 1975;17:92- 101.
  • Hokama A, Uehara T, Nakayoshi T, et al. Utility of endoscopic he- moclipping for colonic diverticular bleeding. Am J Gastroenterol 1997; 92:543-6.
  • Parra-Blanco A, Kaminaga N, Kojima T, et al. Hemoclipping for postpolypectomy and postbiopsy colonic bleeding. Gastrointest Endosc 2000; 51:37-41.
  • Tsunada S, Ogata S, Ohyama T, et al. Endoscopic closure of per- forations caused by EMR in the stomach by application of metallic clips. Gastrointest Endosc 2003; 57:948-51.
  • Cipolletta L, Bianco MA, Marmo R, ve ark. Endoclips versus heater probe in preventing early recurrent bleeding from peptic ulcer: a prospective and randomized trial. Gastrointest Endosc 2001;53:147-51.
  • Lin HJ, Hsieh YH, Tseng GY, et al. A prospective randomized trial of endoscopic hemoclip versus heater probe thermocoagulation for peptic ulcer bleeding. Am J Gastroenterol 2002; 97:2250-4.
  • Yuan Y, Wang C, Hunt RH. Endoscopic clipping for acute nonvari- ceal upper-GI bleeding: a meta-analysis and critical appraisal of ran- domized controlled trials. Gastrointest Endosc 2008; 68:339-51.
  • Huang SP, Wang HP, Lee YC, et al. Endoscopic hemoclip placement and epinephrine injection for Mallory-Weiss syndrome with active bleeding. Gastrointest Endosc 2002; 55:842-6.
  • Park CH, Sohn YH, Lee WS, et al. The usefulness of endoscopic hemoclipping for bleeding Dieulafoy lesions. Endoscopy 2003: 35:388-92.
Toplam 17 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Bölüm Makaleler
Yazarlar

Hüseyin Köseoğlu Bu kişi benim

Fatma Ebru Akın Bu kişi benim

Aylin Demirezer Bolat Bu kişi benim

Tevfik Solakoğlu - Bu kişi benim

Roni Atalay

Sevil Özer Sarı Bu kişi benim

Eyüp Selvi Bu kişi benim

Öykü Tayfur Yürekli Bu kişi benim

Naciye Şemnur Büyükaşık Bu kişi benim

Osman Ersoy - Bu kişi benim

Yayımlanma Tarihi 1 Nisan 2014
Yayımlandığı Sayı Yıl 2014 Cilt: 13 Sayı: 1

Kaynak Göster

APA Köseoğlu, H., Akın, F. E., Bolat, A. D., -, T. S., vd. (2014). Varis dışı üst GİS kanamalı hastalarda endoskopik klip uygulamalarımız. Akademik Gastroenteroloji Dergisi, 13(1), 13-17. https://doi.org/10.17941/agd.57679

test-5