Beyond glycemic control: The pleiotropic potential of SGLT-2 inhibitors
Öz
Anahtar Kelimeler
Etik Beyan
Kaynakça
- Sano R, Shinozaki Y, Ohta T. Sodium-glucose cotransporters: functional properties and pharmaceutical potential. J Diabetes Investig. 2020;11(4):770–82.
- Brown E, Heerspink HJL, Cuthbertson DJ, Wilding JPH. SGLT2 inhibitors and GLP-1 receptor agonists: established and emerging indications. Lancet. 2021;398(10296):262–76.
- Bendotti G, Montefusco L, Pastore I, Lazzaroni E, Lunati ME, Fiorina P. The anti-inflammatory and immunological properties of SGLT-2 inhibitors. J Endocrinol Invest. 2023;46(12):2445–52.
- White JR. Apple trees to sodium glucose co-transporter inhibitors: a review of SGLT2 inhibition. Clin Diabetes. 2010;28(1):5–10.
- Rossetti L, Smith D, Shulman GI, Papachristou D, DeFronzo RA. Correction of hyperglycemia with phlorizin normalizes tissue sensitivity to insulin in diabetic rats. J Clin Invest. 1987;79(5):1510–5.
- Blondel O, Bailbe D, Portha B. Insulin resistance in rats with non-insulin-dependent diabetes induced by neonatal (5 days) streptozotocin: evidence for reversal following phlorizin treatment. Metabolism. 1990;39(8):787–93.
- Brichard SM, Henquin JC, Girard J. Phlorizin treatment of diabetic rats partially reverses the abnormal expression of genes involved in hepatic glucose metabolism. Diabetologia. 1993;36:292–8.
- Helvacı Ö, Helvacı B. A story of serendipities: from phlorizin to gliflozins. Exp Clin Transplant. 2023;21(Suppl 2):105–8.
Ayrıntılar
Birincil Dil
İngilizce
Konular
İç Hastalıkları
Bölüm
Editoryal
Yazarlar
Selma Sezen
*
0000-0001-6575-6149
Türkiye
Yayımlanma Tarihi
29 Ekim 2025
Gönderilme Tarihi
26 Ekim 2025
Kabul Tarihi
27 Ekim 2025
Yayımlandığı Sayı
Yıl 2025 Cilt: 3 Sayı: 3